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AR248132A1 - Un nuevo metodo para la preparacion de 9-amino-1, 2, 3, 4-tetrahidroacridina y para la preparacion de hidrocloruro de tacrina. - Google Patents

Un nuevo metodo para la preparacion de 9-amino-1, 2, 3, 4-tetrahidroacridina y para la preparacion de hidrocloruro de tacrina.

Info

Publication number
AR248132A1
AR248132A1 AR92321794A AR32179492A AR248132A1 AR 248132 A1 AR248132 A1 AR 248132A1 AR 92321794 A AR92321794 A AR 92321794A AR 32179492 A AR32179492 A AR 32179492A AR 248132 A1 AR248132 A1 AR 248132A1
Authority
AR
Argentina
Prior art keywords
tetrahydroacridine
amino
acid
preparation
ethos
Prior art date
Application number
AR92321794A
Other languages
English (en)
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Application granted granted Critical
Publication of AR248132A1 publication Critical patent/AR248132A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08—Nitrogen atoms
    • C07D219/10—Nitrogen atoms attached in position 9

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

UN METODO PARA PREPARAR 9-AMINO-1, 2, 3, 4-TETRAHIDROACRIDINA, QUE COMPRENDE HACER REACCIONAR 2-AMINOBENZONITRILO Y CICLOHEXANONA EN PRESENCIA DE UN CATALIZADOR ACIDO EN UN DISOLVENTE COMO XILENOS, TOLUENO, ETERES AROMATICOS, TALES COMO ANISOL Y DIMETOXIBENCENO, Y COMPUESTOS AROMATICOS HALOGENADOS, TALES COMO CLOROBENCENO Y DICLOROBENCENO Y DONDE EL CATALIZADOR ACIDO ES ACIDO P-TOLUENSULFONICO MONOHIDRATO, ACIDO METANSULFONICO Y ACIDO SULFURICO.
AR92321794A 1991-02-19 1992-02-17 Un nuevo metodo para la preparacion de 9-amino-1, 2, 3, 4-tetrahidroacridina y para la preparacion de hidrocloruro de tacrina. AR248132A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/656,389 US5155226A (en) 1991-02-19 1991-02-19 Method for the preparation of 9-amino-1,2,3,4-tetrahydroacridine

Publications (1)

Publication Number Publication Date
AR248132A1 true AR248132A1 (es) 1995-06-30

Family

ID=24632830

Family Applications (1)

Application Number Title Priority Date Filing Date
AR92321794A AR248132A1 (es) 1991-02-19 1992-02-17 Un nuevo metodo para la preparacion de 9-amino-1, 2, 3, 4-tetrahidroacridina y para la preparacion de hidrocloruro de tacrina.

Country Status (24)

Country Link
US (1) US5155226A (es)
EP (1) EP0500006B1 (es)
JP (1) JP2782698B2 (es)
AR (1) AR248132A1 (es)
AT (1) ATE144980T1 (es)
AU (1) AU639656B2 (es)
BR (1) BR9200524A (es)
CA (1) CA2061422A1 (es)
CZ (1) CZ280649B6 (es)
DE (1) DE69214974T2 (es)
DK (1) DK0500006T3 (es)
ES (1) ES2095338T3 (es)
FI (1) FI97542C (es)
GR (1) GR3021687T3 (es)
HU (1) HU212942B (es)
IE (1) IE76739B1 (es)
IL (1) IL100970A (es)
MX (1) MX9200672A (es)
NO (1) NO178110C (es)
NZ (1) NZ241624A (es)
PH (1) PH29991A (es)
PL (1) PL166949B1 (es)
RU (1) RU2076099C1 (es)
ZA (1) ZA921160B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5053513A (en) * 1990-03-29 1991-10-01 Hoechst-Roussel Pharmaceuticals Incorporated Method of reducing a carbonyl containing acridine
ATE189391T1 (de) * 1993-11-26 2000-02-15 Karla Lehmann Verwendung von lithiumverbindungen zur behandlung und prophylaxe des morbus alzheimer
WO1999021561A1 (en) * 1997-10-29 1999-05-06 Davis Bonnie M Method for treatment of disorders of attention
KR100639543B1 (ko) 1998-09-30 2006-10-31 다케다 야쿠힌 고교 가부시키가이샤 방광 배출력 개선제
US20020177593A1 (en) * 1998-09-30 2002-11-28 Yuji Ishihara Agents and crystals for improving excretory potency of urinary bladder
CN105503840B (zh) * 2015-12-04 2019-02-01 广东工业大学 一种含三氮唑基的他克林-香豆素衍生物及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0268871A1 (en) * 1986-10-31 1988-06-01 Sumitomo Pharmaceuticals Company, Limited Quinoline derivatives
IL87861A0 (en) * 1987-10-05 1989-03-31 Pfizer 4-aminopyridine derivatives
GB8827704D0 (en) * 1988-11-28 1988-12-29 Fujisawa Pharmaceutical Co New acridine derivatives & processes for their production
FR2640508B1 (fr) * 1988-12-19 1994-07-01 Dietlin Francois Nouvelles compositions et nouveaux produits pharmaceutiques assurant la regeneration de leucocytes et leur emploi pour le traitement du syndrome immuno-deficitaire

Also Published As

Publication number Publication date
PL166949B1 (pl) 1995-07-31
IE920510A1 (en) 1992-08-26
ATE144980T1 (de) 1996-11-15
FI920675A0 (fi) 1992-02-17
HU212942B (en) 1996-12-30
ES2095338T3 (es) 1997-02-16
CZ280649B6 (cs) 1996-03-13
FI97542C (fi) 1997-01-10
DE69214974T2 (de) 1997-05-22
BR9200524A (pt) 1992-10-20
FI97542B (fi) 1996-09-30
HU9200515D0 (en) 1992-05-28
RU2076099C1 (ru) 1997-03-27
EP0500006B1 (en) 1996-11-06
EP0500006A1 (en) 1992-08-26
IL100970A (en) 1996-03-31
IL100970A0 (en) 1992-11-15
US5155226A (en) 1992-10-13
FI920675L (fi) 1992-08-20
HUT64032A (en) 1993-11-29
JP2782698B2 (ja) 1998-08-06
AU1107392A (en) 1992-08-27
CA2061422A1 (en) 1992-08-20
DE69214974D1 (de) 1996-12-12
JPH04346975A (ja) 1992-12-02
NO920636D0 (no) 1992-02-18
PH29991A (en) 1996-10-29
PL293510A1 (en) 1992-10-19
NO920636L (no) 1992-08-20
GR3021687T3 (en) 1997-02-28
DK0500006T3 (da) 1997-04-07
AU639656B2 (en) 1993-07-29
CS47792A3 (en) 1992-09-16
NO178110B (no) 1995-10-16
IE76739B1 (en) 1997-11-05
NO178110C (no) 1996-01-24
NZ241624A (en) 1994-03-25
ZA921160B (en) 1992-10-28
MX9200672A (es) 1992-08-01

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