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AR246521A1 - Un procedimiento para la preparacion de derivados del cromeno. - Google Patents

Un procedimiento para la preparacion de derivados del cromeno.

Info

Publication number
AR246521A1
AR246521A1 AR88312155A AR31215588A AR246521A1 AR 246521 A1 AR246521 A1 AR 246521A1 AR 88312155 A AR88312155 A AR 88312155A AR 31215588 A AR31215588 A AR 31215588A AR 246521 A1 AR246521 A1 AR 246521A1
Authority
AR
Argentina
Prior art keywords
pharmaceutical compositions
preparation process
compositions containing
chromene derivatives
dimethyl
Prior art date
Application number
AR88312155A
Other languages
English (en)
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Application granted granted Critical
Publication of AR246521A1 publication Critical patent/AR246521A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

PROCEDIMIENTO DE PREPARACION DE DERIVADOS DEL DIMETIL-2,2-CROMENO DE FORMULA (I) EN LA CUAL Z ES GRUPO CIANO, FOSFONO O DIALCOXI-FOSFORILO, DONDE SE DESHIDRATA UN CROMANOL-3 DE FORMULA (II), EN LA CUAL Z' ES CIANO, O DIALCOXIFOSFORILO, POR UN HIDRURO ALCALINO Y PORQUE SE TRANSFORMA EVENTUALMENTE EL GRUPO DIALCOXIFOSFORILO EN EL GRUPO FOSFONO, Y LUEGO PORQUE SE TRANSFORMA EVENTUALMENTE EL ACIDO FOSFONICO ASI OBTENIDO EN UNA DE SUS SALES FARMACEUTICAMENTE ACEPTABLES.
AR88312155A 1987-10-12 1988-10-11 Un procedimiento para la preparacion de derivados del cromeno. AR246521A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8714067A FR2621587B1 (fr) 1987-10-12 1987-10-12 Derives du dimethyl-2,2 chromene, procede pour leur preparation et composition pharmaceutiques les contenant

Publications (1)

Publication Number Publication Date
AR246521A1 true AR246521A1 (es) 1994-08-31

Family

ID=9355735

Family Applications (1)

Application Number Title Priority Date Filing Date
AR88312155A AR246521A1 (es) 1987-10-12 1988-10-11 Un procedimiento para la preparacion de derivados del cromeno.

Country Status (18)

Country Link
US (1) US5391751A (es)
EP (2) EP0312432B1 (es)
JP (1) JPH02180A (es)
KR (1) KR890006625A (es)
AR (1) AR246521A1 (es)
AT (1) ATE100095T1 (es)
AU (1) AU619766B2 (es)
CA (1) CA1329603C (es)
DE (1) DE3887068D1 (es)
DK (1) DK567188A (es)
FI (1) FI90545C (es)
FR (1) FR2621587B1 (es)
IE (1) IE940342L (es)
IL (1) IL88002A (es)
NO (1) NO171851C (es)
NZ (1) NZ226516A (es)
PT (1) PT88718B (es)
ZA (1) ZA887607B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5387587A (en) * 1986-12-23 1995-02-07 Merck Patent Gesellschaft Mit Beschrankter Haftung Chroman derivatives
DE3726261A1 (de) * 1986-12-23 1988-07-07 Merck Patent Gmbh Chromanderivate
US5284838A (en) * 1987-06-23 1994-02-08 Elf Sanofi Use of 2,2-dimethylchroman-3-ol derivatives in the treatment of asthma
AU3553489A (en) * 1988-05-09 1989-11-29 Beecham Group Plc Novel compounds and treatment
EP0346724A1 (de) * 1988-06-16 1989-12-20 MERCK PATENT GmbH Chromanderivate
EP0376524B1 (en) * 1988-12-13 1995-03-29 Beecham Group Plc Benzopyran and related compounds
DE3923839A1 (de) * 1989-07-19 1991-01-31 Beiersdorf Ag Benzopyran-derivate, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen
DE3924417A1 (de) * 1989-07-24 1991-01-31 Merck Patent Gmbh Chromanderivate
FR2657872B2 (fr) * 1989-11-06 1992-06-12 Sanofi Sa Derive d'amidino-4 chromanne, procede d'obtention et compositions pharmaceutiques le contenant.
FR2654103B1 (fr) * 1989-11-06 1992-02-21 Sanofi Sa Derives d'amidino-4 chromanne, procede d'obtention et compositions pharmaceutiques les contenant.
US5185345A (en) * 1989-11-06 1993-02-09 Sanofi 4-amidino pyrano (3,2-c) pyridine derivatives, and pharmaceutical compositions containing them
US5177616A (en) * 1991-12-02 1993-01-05 Matsushita Avionics Systems Stowable video display assembly
DE102004005179B4 (de) * 2004-02-02 2006-07-13 Wobben, Aloys, Dipl.-Ing. Windenergieanlage

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE23718T1 (de) * 1981-09-25 1986-12-15 Beecham Group Plc Benzopyran-verbindungen mit pharmazeutischer wirkung.
GB8521857D0 (en) * 1985-09-03 1985-10-09 Beecham Group Plc Active compounds
DE3726261A1 (de) * 1986-12-23 1988-07-07 Merck Patent Gmbh Chromanderivate
EP0346724A1 (de) * 1988-06-16 1989-12-20 MERCK PATENT GmbH Chromanderivate
EP0376524B1 (en) * 1988-12-13 1995-03-29 Beecham Group Plc Benzopyran and related compounds

Also Published As

Publication number Publication date
AU2366088A (en) 1989-04-13
PT88718B (pt) 1992-12-31
IL88002A (en) 1994-08-26
EP0312432B1 (fr) 1994-01-12
KR890006625A (ko) 1989-06-14
IE940342L (en) 1989-04-12
FI884660A0 (fi) 1988-10-11
EP0556872A1 (fr) 1993-08-25
IL88002A0 (en) 1989-06-30
FI90545C (fi) 1994-02-25
DK567188D0 (da) 1988-10-11
JPH02180A (ja) 1990-01-05
US5391751A (en) 1995-02-21
NO171851B (no) 1993-02-01
ZA887607B (en) 1989-06-28
NO171851C (no) 1993-05-12
DK567188A (da) 1989-04-13
NO884533L (no) 1989-04-13
FR2621587B1 (fr) 1990-02-09
DE3887068D1 (de) 1994-02-24
FI884660L (fi) 1989-04-13
CA1329603C (en) 1994-05-17
NO884533D0 (no) 1988-10-11
AU619766B2 (en) 1992-02-06
EP0312432A1 (fr) 1989-04-19
FI90545B (fi) 1993-11-15
FR2621587A1 (fr) 1989-04-14
ATE100095T1 (de) 1994-01-15
NZ226516A (en) 1990-05-28

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