AR246513A1 - Metodo para la preparacion de acidos piridin-2,3-dicarboxilicos. - Google Patents
Metodo para la preparacion de acidos piridin-2,3-dicarboxilicos.Info
- Publication number
- AR246513A1 AR246513A1 AR89313384A AR31338489A AR246513A1 AR 246513 A1 AR246513 A1 AR 246513A1 AR 89313384 A AR89313384 A AR 89313384A AR 31338489 A AR31338489 A AR 31338489A AR 246513 A1 AR246513 A1 AR 246513A1
- Authority
- AR
- Argentina
- Prior art keywords
- substituted
- hydroxy
- dicarboxylic acids
- quinolines
- pyridine
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- -1 substituted-8-hydroxy-quinolines Chemical class 0.000 title 2
- 230000003647 oxidation Effects 0.000 title 1
- 238000007254 oxidation reaction Methods 0.000 title 1
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 abstract 2
- 239000007864 aqueous solution Substances 0.000 abstract 2
- WQYVRQLZKVEZGA-UHFFFAOYSA-N hypochlorite Chemical compound Cl[O-] WQYVRQLZKVEZGA-UHFFFAOYSA-N 0.000 abstract 2
- 239000005725 8-Hydroxyquinoline Substances 0.000 abstract 1
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical class [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 229960003540 oxyquinoline Drugs 0.000 abstract 1
- MCJGNVYPOGVAJF-UHFFFAOYSA-N quinolin-8-ol Chemical compound C1=CN=C2C(O)=CC=CC2=C1 MCJGNVYPOGVAJF-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/803—Processes of preparation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Quinoline Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
UN METODO PARA LA PREPARACION DE ACIDOS PIRIDIN-2,3-DICARBOXILICOS DE FORMULA (I) EN DONDE Y ES HIDROGENO O ALQUILO, OBTENIDOS POR HACER REACCIONAR UN COMPUESTO DE 8-HIDROXI-QUINOLINA DE LA FORMULA (II), CON APROXIMADAMENTE 7 A 14 EQUIVALENTES MOLARES DE PEROXIDO DE HIDROGENO COMO UNA SOLUCION ACUOSA DE 30%-50% EN PRESENCIA 5,5 EQUIVALENTES MOLARES DE BASE ACUOSA Y MANTENER, AGREGAR ACIDO MINERAL PARA OBTENER UN PH DE APROXIMADAMENTE 8-13, LUEGO AGREGAR APROXIMADAMENTE 1,0-2,0 EQUIVALENTES MOLARES DE HIPOCLORITO CON UNA SOLUCION ACUOSA AL 5%-30% O GENERADO IN SITU MEDIANTE LA ADICION DE GAS CLORO Y LUEGO DE UNA O DOS HORAS A 65-75*C, AISLAR EL PRODUCTO DE ACIDO DICARBOXILICO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16635988A | 1988-03-10 | 1988-03-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR246513A1 true AR246513A1 (es) | 1994-08-31 |
Family
ID=22602953
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AR89313384A AR246513A1 (es) | 1988-03-10 | 1989-03-09 | Metodo para la preparacion de acidos piridin-2,3-dicarboxilicos. |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0331899B1 (es) |
| JP (1) | JP2689394B2 (es) |
| KR (1) | KR970011790B1 (es) |
| CN (1) | CN1027813C (es) |
| AR (1) | AR246513A1 (es) |
| AT (1) | ATE104964T1 (es) |
| AU (1) | AU611000B2 (es) |
| BR (1) | BR8901092A (es) |
| CA (1) | CA1327584C (es) |
| DE (1) | DE68914869T2 (es) |
| DK (1) | DK169671B1 (es) |
| ES (1) | ES2063061T3 (es) |
| HU (1) | HU206085B (es) |
| IE (1) | IE64009B1 (es) |
| IL (1) | IL89142A (es) |
| TW (1) | TW198714B (es) |
| ZA (1) | ZA891821B (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2058625T3 (es) | 1989-03-22 | 1994-11-01 | American Cyanamid Co | Metodo para la oxidacion secuencial de quinolinas sustituidas para producir acidos piridin-2,3-dicarboxilicos sustituidos. |
| US5281713A (en) * | 1991-12-20 | 1994-01-25 | American Cyanamid Company | Process for the manufacture of 2-alkoxymethylacrolein |
| ATE165347T1 (de) * | 1993-12-28 | 1998-05-15 | American Cyanamid Co | Verfahren zur herstellung pyridin-2,3- dicarboxylicsäure |
| US5597924A (en) * | 1995-05-24 | 1997-01-28 | American Cyanamid Company | Coversion of substituted 8-chloroquinolines to substituted 8-hydroxyquinolines |
| NZ314904A (en) * | 1996-06-10 | 1998-06-26 | American Cyanamid Co | Preparation of a herbicidal [(5,6-dicarboxy-3-pyridyl)methyl]ammonium halide |
| CN109225323B (zh) * | 2018-10-26 | 2021-07-27 | 闽江学院 | 磺酸基官能化有机/无机双阳离子-钒掺杂杂多酸阴离子复合杂化体及其合成与应用 |
| CN113813895B (zh) * | 2021-07-20 | 2023-03-31 | 上海罕道医药科技有限公司 | 一种连续反应装置与一种5-硝基吡啶-3-甲酸的连续制备方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0259687B1 (en) * | 1986-09-12 | 1991-07-03 | American Cyanamid Company | Method for the preparation of pyridine-2,3-dicarboxylic acids |
-
1989
- 1989-02-01 IL IL89142A patent/IL89142A/xx unknown
- 1989-02-02 AT AT8989101766T patent/ATE104964T1/de not_active IP Right Cessation
- 1989-02-02 ES ES89101766T patent/ES2063061T3/es not_active Expired - Lifetime
- 1989-02-02 DE DE68914869T patent/DE68914869T2/de not_active Expired - Lifetime
- 1989-02-02 EP EP89101766A patent/EP0331899B1/en not_active Expired - Lifetime
- 1989-02-24 CN CN89100922A patent/CN1027813C/zh not_active Expired - Lifetime
- 1989-03-07 JP JP1053056A patent/JP2689394B2/ja not_active Expired - Lifetime
- 1989-03-08 CA CA000593053A patent/CA1327584C/en not_active Expired - Lifetime
- 1989-03-09 HU HU891163A patent/HU206085B/hu not_active IP Right Cessation
- 1989-03-09 AU AU31187/89A patent/AU611000B2/en not_active Expired
- 1989-03-09 DK DK114789A patent/DK169671B1/da not_active IP Right Cessation
- 1989-03-09 ZA ZA891821A patent/ZA891821B/xx unknown
- 1989-03-09 KR KR1019890002906A patent/KR970011790B1/ko not_active Expired - Fee Related
- 1989-03-09 BR BR898901092A patent/BR8901092A/pt not_active IP Right Cessation
- 1989-03-09 IE IE76489A patent/IE64009B1/en not_active IP Right Cessation
- 1989-03-09 AR AR89313384A patent/AR246513A1/es active
-
1990
- 1990-07-10 TW TW078101863A01A patent/TW198714B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| DE68914869T2 (de) | 1994-12-08 |
| JP2689394B2 (ja) | 1997-12-10 |
| TW198714B (es) | 1993-01-21 |
| CA1327584C (en) | 1994-03-08 |
| CN1044463A (zh) | 1990-08-08 |
| DK169671B1 (da) | 1995-01-09 |
| AU611000B2 (en) | 1991-05-30 |
| CN1027813C (zh) | 1995-03-08 |
| AU3118789A (en) | 1989-09-14 |
| IE890764L (en) | 1989-09-10 |
| JPH01268677A (ja) | 1989-10-26 |
| EP0331899A3 (en) | 1990-09-12 |
| EP0331899A2 (en) | 1989-09-13 |
| DK114789A (da) | 1989-09-11 |
| DE68914869D1 (de) | 1994-06-01 |
| ES2063061T3 (es) | 1995-01-01 |
| ZA891821B (en) | 1989-11-29 |
| IL89142A0 (en) | 1989-09-10 |
| HU206085B (en) | 1992-08-28 |
| KR890014487A (ko) | 1989-10-24 |
| EP0331899B1 (en) | 1994-04-27 |
| DK114789D0 (da) | 1989-03-09 |
| IL89142A (en) | 1993-04-04 |
| IE64009B1 (en) | 1995-06-28 |
| BR8901092A (pt) | 1989-10-31 |
| KR970011790B1 (ko) | 1997-07-16 |
| ATE104964T1 (de) | 1994-05-15 |
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