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AR222635A1 - PROCEDURE FOR THE PREPARATION OF PHENYLPIPERAZINE DERIVATIVES - Google Patents

PROCEDURE FOR THE PREPARATION OF PHENYLPIPERAZINE DERIVATIVES

Info

Publication number
AR222635A1
AR222635A1 AR271519A AR27151978A AR222635A1 AR 222635 A1 AR222635 A1 AR 222635A1 AR 271519 A AR271519 A AR 271519A AR 27151978 A AR27151978 A AR 27151978A AR 222635 A1 AR222635 A1 AR 222635A1
Authority
AR
Argentina
Prior art keywords
procedure
preparation
phenylpiperazine derivatives
phenylpiperazine
derivatives
Prior art date
Application number
AR271519A
Other languages
Spanish (es)
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Application granted granted Critical
Publication of AR222635A1 publication Critical patent/AR222635A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/24Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40Radicals substituted by oxygen atoms
    • C07D307/42Singly bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/16Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AR271519A 1976-04-23 1978-03-22 PROCEDURE FOR THE PREPARATION OF PHENYLPIPERAZINE DERIVATIVES AR222635A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB16526/76A GB1575904A (en) 1976-04-23 1976-04-23 Phenyl piperazines

Publications (1)

Publication Number Publication Date
AR222635A1 true AR222635A1 (en) 1981-06-15

Family

ID=10078930

Family Applications (2)

Application Number Title Priority Date Filing Date
AR267310A AR222003A1 (en) 1976-04-23 1977-04-22 PROCEDURE FOR THE PREPARATION OF PHENYLPIPERAZINE DERIVATIVES
AR271519A AR222635A1 (en) 1976-04-23 1978-03-22 PROCEDURE FOR THE PREPARATION OF PHENYLPIPERAZINE DERIVATIVES

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AR267310A AR222003A1 (en) 1976-04-23 1977-04-22 PROCEDURE FOR THE PREPARATION OF PHENYLPIPERAZINE DERIVATIVES

Country Status (34)

Country Link
JP (1) JPS52151183A (en)
AR (2) AR222003A1 (en)
AT (1) AT355579B (en)
AU (1) AU514822B2 (en)
BE (1) BE853899A (en)
BG (2) BG28055A3 (en)
CA (1) CA1087617A (en)
CH (2) CH633009A5 (en)
CS (1) CS196360B2 (en)
DD (1) DD129790A5 (en)
DE (1) DE2717415A1 (en)
DK (1) DK176177A (en)
ES (2) ES457988A1 (en)
FI (1) FI63937C (en)
FR (1) FR2348925A1 (en)
GB (1) GB1575904A (en)
GR (1) GR64084B (en)
HU (1) HU176820B (en)
IE (1) IE44730B1 (en)
IL (1) IL51787A (en)
LU (1) LU77170A1 (en)
MX (1) MX4596E (en)
NL (1) NL7704456A (en)
NO (1) NO146710C (en)
NZ (1) NZ183715A (en)
OA (1) OA05643A (en)
PH (1) PH14124A (en)
PL (1) PL117466B1 (en)
PT (1) PT66452B (en)
RO (1) RO72831A (en)
SE (1) SE7704536L (en)
SU (2) SU664564A3 (en)
YU (1) YU104477A (en)
ZA (1) ZA771849B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1601310A (en) * 1978-05-23 1981-10-28 Lilly Industries Ltd Aryl hydantoins
DE3142608A1 (en) * 1981-10-28 1983-05-05 Basf Ag, 6700 Ludwigshafen POLYAZO DYES
JPH07157477A (en) * 1993-12-02 1995-06-20 Asahi Kagaku Kogyo Kk Method for producing thiazole derivative
KR970701705A (en) * 1994-03-11 1997-04-12 오노다 마사요시 5-HT₃ receptor agonists, novel thiazole derivatives, and intermediates thereof
CA2144669A1 (en) * 1994-03-29 1995-09-30 Kozo Akasaka Biphenyl derivatives
GB9517381D0 (en) * 1995-08-24 1995-10-25 Pharmacia Spa Aryl and heteroaryl piperazine derivatives
DZ3292A1 (en) * 2001-09-13 2005-05-14 Solvay Pharm Gmbh Novel 1-[1-(hetero)aryl-1-perhydroxyalkylmethyl]-piperazine compounds, process for their preparation and medicaments containing these compounds
US8927546B2 (en) 2006-02-28 2015-01-06 Dart Neuroscience (Cayman) Ltd. Therapeutic piperazines
AU2007221021B2 (en) 2006-02-28 2013-01-17 Dart Neuroscience (Cayman) Ltd Therapeutic piperazines as PDE4 inhibitors

Also Published As

Publication number Publication date
BE853899A (en) 1977-10-24
FI63937B (en) 1983-05-31
CS196360B2 (en) 1980-03-31
FR2348925A1 (en) 1977-11-18
JPS52151183A (en) 1977-12-15
CA1087617A (en) 1980-10-14
ATA285177A (en) 1979-08-15
NZ183715A (en) 1980-04-28
FI771287A7 (en) 1977-10-24
RO72831B (en) 1983-07-30
ES457988A1 (en) 1978-07-16
SU664564A3 (en) 1979-05-25
NL7704456A (en) 1977-10-25
NO146710C (en) 1982-11-24
ZA771849B (en) 1978-11-29
PH14124A (en) 1981-02-26
FR2348925B1 (en) 1980-04-11
DD129790A5 (en) 1978-02-08
SU727146A3 (en) 1980-04-05
AU2438677A (en) 1978-10-26
BG27746A3 (en) 1979-12-12
AU514822B2 (en) 1981-02-26
FI63937C (en) 1983-09-12
GB1575904A (en) 1980-10-01
ES467948A1 (en) 1978-11-01
IE44730B1 (en) 1982-03-10
PT66452B (en) 1979-03-09
IL51787A0 (en) 1977-05-31
CH633009A5 (en) 1982-11-15
YU104477A (en) 1983-01-21
OA05643A (en) 1981-04-30
AR222003A1 (en) 1981-04-15
PT66452A (en) 1977-05-01
HU176820B (en) 1981-05-28
PL117466B1 (en) 1981-08-31
PL197550A1 (en) 1979-05-21
DE2717415A1 (en) 1977-11-10
NO771398L (en) 1977-10-25
RO72831A (en) 1983-08-03
CH625802A5 (en) 1981-10-15
NO146710B (en) 1982-08-16
AT355579B (en) 1980-03-10
LU77170A1 (en) 1979-01-18
SE7704536L (en) 1977-10-24
BG28055A3 (en) 1980-02-25
DK176177A (en) 1977-10-24
IE44730L (en) 1977-10-23
GR64084B (en) 1980-01-21
MX4596E (en) 1982-06-25
IL51787A (en) 1980-02-29

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