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AR133199A1 - Macrociclos bicíclicos para el tratamiento de enfermedades autoinmunitarias - Google Patents

Macrociclos bicíclicos para el tratamiento de enfermedades autoinmunitarias

Info

Publication number
AR133199A1
AR133199A1 ARP240101777A ARP240101777A AR133199A1 AR 133199 A1 AR133199 A1 AR 133199A1 AR P240101777 A ARP240101777 A AR P240101777A AR P240101777 A ARP240101777 A AR P240101777A AR 133199 A1 AR133199 A1 AR 133199A1
Authority
AR
Argentina
Prior art keywords
treatment
autoimmune diseases
bicyclic macrocycles
macrocycles
bicyclic
Prior art date
Application number
ARP240101777A
Other languages
English (en)
Inventor
Buyu Kou
Haixia Liu
Hong Shen
Yao Wu
Zhiwei Zhan
Wei Zhu
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of AR133199A1 publication Critical patent/AR133199A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

La presente invención se refiere a compuestos de fórmula (1a), en donde R², T¹ a T⁴, y M¹ a M³ son como se describe en la presente, y su sal farmacéuticamente aceptable, y composiciones que incluyen los compuestos y métodos de uso de los compuestos.
ARP240101777A 2023-07-10 2024-07-08 Macrociclos bicíclicos para el tratamiento de enfermedades autoinmunitarias AR133199A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2023106598 2023-07-10

Publications (1)

Publication Number Publication Date
AR133199A1 true AR133199A1 (es) 2025-09-03

Family

ID=91946408

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP240101777A AR133199A1 (es) 2023-07-10 2024-07-08 Macrociclos bicíclicos para el tratamiento de enfermedades autoinmunitarias

Country Status (3)

Country Link
AR (1) AR133199A1 (es)
TW (1) TW202517654A (es)
WO (1) WO2025012195A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025228902A1 (en) 2024-04-30 2025-11-06 Boehringer Ingelheim International Gmbh Heterocyclic acids as sting antagonists and the use thereof as medicament
WO2025228900A1 (en) 2024-04-30 2025-11-06 Boehringer Ingelheim International Gmbh Arylamide substituted indazoles and the use thereof as medicament
WO2025228889A1 (en) 2024-04-30 2025-11-06 Boehringer Ingelheim International Gmbh Monoarylic heterocyclic compounds as sting antagonists and the use thereof as medicament
US20250333414A1 (en) 2024-04-30 2025-10-30 Boehringer Ingelheim International Gmbh Hetaryl substituted indazoles and benzimidazoles as sting antagonists and the use thereof as medicament
WO2025228892A1 (en) 2024-04-30 2025-11-06 Boehringer Ingelheim International Gmbh Monoaryl and hetaryl substituted indazoles and benzimidazoles as sting antagonists and the use thereof as medicament
WO2025228899A1 (en) 2024-04-30 2025-11-06 Boehringer Ingelheim International Gmbh Further heterocyclic compounds as sting antagonists and the use thereof as medicament

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10975287B2 (en) 2016-04-07 2021-04-13 Glaxosmithkline Intellectual Property Development Limited Heterocyclic amides useful as protein modulators
AU2017247798C1 (en) * 2016-04-07 2020-08-27 Glaxosmithkline Intellectual Property Development Limited Heterocyclic amides useful as protein modulators
WO2022015977A1 (en) * 2020-07-15 2022-01-20 Ifm Due, Inc. Compounds and compositions for treating conditions associated with sting activity
WO2023148129A1 (en) * 2022-02-02 2023-08-10 F. Hoffmann-La Roche Ag Imidazole macrocycles for the treatment of autoimmune disease

Also Published As

Publication number Publication date
WO2025012195A1 (en) 2025-01-16
TW202517654A (zh) 2025-05-01

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