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AR130140A2 - Métodos para evaluar conveniencia de un filtro bioquímico - Google Patents

Métodos para evaluar conveniencia de un filtro bioquímico

Info

Publication number
AR130140A2
AR130140A2 ARP230102079A ARP230102079A AR130140A2 AR 130140 A2 AR130140 A2 AR 130140A2 AR P230102079 A ARP230102079 A AR P230102079A AR P230102079 A ARP230102079 A AR P230102079A AR 130140 A2 AR130140 A2 AR 130140A2
Authority
AR
Argentina
Prior art keywords
methods
suitability
evaluating
filters
biochemical filter
Prior art date
Application number
ARP230102079A
Other languages
English (en)
Inventor
Nathan Mao
Annamarie Cruz
Bernhard Schilling
Scott Carver
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of AR130140A2 publication Critical patent/AR130140A2/es

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D24/00—Filters comprising loose filtering material, i.e. filtering material without any binder between the individual particles or fibres thereof
    • B01D24/02—Filters comprising loose filtering material, i.e. filtering material without any binder between the individual particles or fibres thereof with the filter bed stationary during the filtration
    • B01D24/10—Filters comprising loose filtering material, i.e. filtering material without any binder between the individual particles or fibres thereof with the filter bed stationary during the filtration the filtering material being held in a closed container
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M37/00—Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
    • C12M37/02—Filters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/538—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by sorbent column, particles or resin strip, i.e. sorbent materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/579—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving limulus lysate
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Realizaciones de la presente revelación incluyen métodos y sistemas para detectar la presencia de endotoxinas en filtros. Por ejemplo, realizaciones de la presente revelación se dirigen a métodos y sistemas para mejorar controles en procesos mediante detección de cantidades no deseadas de endotoxinas en filtros que contienen materiales que provienen de fuentes que se dan naturalmente previo a usar aquellos filtros en la producción de sustancias farmacéuticas formuladas.
ARP230102079A 2018-05-02 2023-08-07 Métodos para evaluar conveniencia de un filtro bioquímico AR130140A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201862665721P 2018-05-02 2018-05-02

Publications (1)

Publication Number Publication Date
AR130140A2 true AR130140A2 (es) 2024-11-06

Family

ID=67106126

Family Applications (3)

Application Number Title Priority Date Filing Date
ARP190101127A AR114848A1 (es) 2018-05-02 2019-04-29 Métodos para evaluar conveniencia de un filtro bioquímico
ARP220103612A AR128130A2 (es) 2018-05-02 2022-12-27 Métodos para evaluar conveniencia de un filtro bioquímico
ARP230102079A AR130140A2 (es) 2018-05-02 2023-08-07 Métodos para evaluar conveniencia de un filtro bioquímico

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ARP190101127A AR114848A1 (es) 2018-05-02 2019-04-29 Métodos para evaluar conveniencia de un filtro bioquímico
ARP220103612A AR128130A2 (es) 2018-05-02 2022-12-27 Métodos para evaluar conveniencia de un filtro bioquímico

Country Status (7)

Country Link
US (2) US11378571B2 (es)
EP (2) EP3787766B1 (es)
CN (2) CN112020384B (es)
AR (3) AR114848A1 (es)
CA (1) CA3097903A1 (es)
TW (1) TWI814812B (es)
WO (1) WO2019212881A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI814812B (zh) * 2018-05-02 2023-09-11 美商里珍納龍藥品有限公司 用於評估生化過濾器的適合性的方法
CN114602237B (zh) * 2022-03-10 2023-11-28 华兰生物工程股份有限公司 一种从人血浆或人血浆衍生原料中去除内毒素的方法

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AUPM388494A0 (en) * 1994-02-16 1994-03-10 Csl Limited Process for removing endotoxins
DE69623196T3 (de) * 1995-06-30 2019-11-21 Toray Industries, Inc. Permselektive Membranen und Verfahren zu ihrer Herstellung
US6953686B1 (en) * 1999-05-28 2005-10-11 Cambrex Bio Science Baltimore, Inc. Methods of DNA purification and purified DNA
US7306799B2 (en) 1999-06-08 2007-12-11 Regeneron Pharmaceuticals, Inc. Use of VEGF inhibitors for treatment of eye disorders
US7087411B2 (en) 1999-06-08 2006-08-08 Regeneron Pharmaceuticals, Inc. Fusion protein capable of binding VEGF
US7070959B1 (en) 1999-06-08 2006-07-04 Regeneron Pharmaceuticals, Inc. Modified chimeric polypeptides with improved pharmacokinetic properties
US7303746B2 (en) 1999-06-08 2007-12-04 Regeneron Pharmaceuticals, Inc. Methods of treating eye disorders with modified chimeric polypeptides
US7083987B2 (en) * 2001-02-05 2006-08-01 Activx Biosciences, Inc. Activity based probe analysis
US6942802B2 (en) * 2001-04-13 2005-09-13 Wyeth Holdings Corporation Removal of bacterial endotoxin in a protein solution by immobilized metal affinity chromatography
EP1402014A1 (en) * 2001-06-29 2004-03-31 Hemebiotech A/S A process for purification of recombinant porphobilinogen deaminase
FR2840992B1 (fr) * 2002-06-18 2004-09-03 Hemosystem Procede de denombrement et/ou d'identification morphologique de leucocytes en phase solide
WO2006088650A2 (en) 2005-02-02 2006-08-24 Regeneron Pharmaceuticals, Inc. Method of treating eye injury with local administration of a vegf inhibitor
DK2364691T3 (da) 2006-06-16 2013-07-01 Regeneron Pharma VEGF antagonist-formuleringer, der kan anvendes til intravitreal administration
US20110159130A1 (en) * 2007-02-28 2011-06-30 Sanjay Jain Reduction of endotoxin in polysialic acids
PT2153260T (pt) * 2007-05-23 2017-04-24 Vgxi Inc Composição que compreende uma alta concentração de moléculas biologicamente ativas e processos de preparação da mesma
DE102008037678A1 (de) * 2008-08-14 2010-02-25 Sartorius Stedim Biotech Gmbh Tiefenfilterschicht mit anorganischem Schichtdoppelhydroxid
FI3604324T3 (fi) * 2008-08-14 2024-05-16 Genentech Inc Menetelmiä epäpuhtauden poistamiseksi käyttäen luontaisen proteiinin syrjäytyksen ioninvaihtomembraanikromatografiaa
US8277649B2 (en) * 2009-12-14 2012-10-02 General Electric Company Membranes and associated methods for purification of antibodies
TWI589299B (zh) 2011-10-11 2017-07-01 再生元醫藥公司 用於治療類風濕性關節炎之組成物及其使用方法
US9943594B2 (en) 2011-10-11 2018-04-17 Sanofi Biotechnology Methods for the treatment of rheumatoid arthritis
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US10111953B2 (en) 2013-05-30 2018-10-30 Regeneron Pharmaceuticals, Inc. Methods for reducing remnant cholesterol and other lipoprotein fractions by administering an inhibitor of proprotein convertase subtilisin kexin-9 (PCSK9)
TWI697334B (zh) 2013-06-04 2020-07-01 美商再生元醫藥公司 藉由投與ｉｌ-４ｒ抑制劑以治療過敏及增強過敏原-特異之免疫療法的方法
CN105492101B (zh) * 2013-08-30 2019-05-28 Emd密理博公司 具有低可提取物的高容量复合深层过滤介质
US20160152717A1 (en) 2014-12-02 2016-06-02 Regeneron Pharmaceuticals, Inc. Methods for treating dry eye disease by administering an il-6r antagonist
CN105251049B (zh) * 2015-09-29 2018-04-10 浙江星月生物科技股份有限公司 一种去除生物医用材料中细菌内毒素的离子缓冲液及应用
TWI814812B (zh) * 2018-05-02 2023-09-11 美商里珍納龍藥品有限公司 用於評估生化過濾器的適合性的方法

Also Published As

Publication number Publication date
AR114848A1 (es) 2020-10-21
US20190339254A1 (en) 2019-11-07
EP3787766B1 (en) 2025-09-17
US20220404335A1 (en) 2022-12-22
US11378571B2 (en) 2022-07-05
TW202348297A (zh) 2023-12-16
AR128130A2 (es) 2024-03-27
TW201946687A (zh) 2019-12-16
CN112020384A (zh) 2020-12-01
WO2019212881A1 (en) 2019-11-07
TWI814812B (zh) 2023-09-11
EP4657068A3 (en) 2026-01-21
CN116212464A (zh) 2023-06-06
EP3787766A1 (en) 2021-03-10
EP4657068A2 (en) 2025-12-03
CN112020384B (zh) 2023-03-10
CA3097903A1 (en) 2019-11-07

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