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AR129979A1 - Compuestos cíclicos y métodos de uso de estos - Google Patents

Compuestos cíclicos y métodos de uso de estos

Info

Publication number
AR129979A1
AR129979A1 ARP230101908A ARP230101908A AR129979A1 AR 129979 A1 AR129979 A1 AR 129979A1 AR P230101908 A ARP230101908 A AR P230101908A AR P230101908 A ARP230101908 A AR P230101908A AR 129979 A1 AR129979 A1 AR 129979A1
Authority
AR
Argentina
Prior art keywords
methods
cyclic compounds
pharmaceutically acceptable
acceptable salt
compound
Prior art date
Application number
ARP230101908A
Other languages
English (en)
Inventor
Shelby Ellery
Shulu Feng
Jiaye Guo
Goran Krilov
Zhe Nie
Andrew Placzek
Michael Trzoss
Ana Negri
Mats Svensson
Robert Pelletier
Original Assignee
Schroedinger Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schroedinger Inc filed Critical Schroedinger Inc
Publication of AR129979A1 publication Critical patent/AR129979A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Un compuesto de la fórmula (1), o una sal aceptable desde el punto de vista farmacéutico de este. Una composición farmacéutica que comprende un compuesto de acuerdo con cualquiera de las reivindicaciones 1 - 39, o una sal aceptable desde el punto de vista farmacéutico de este, en combinación con uno o más excipientes aceptables desde el punto de vista farmacéutico.
ARP230101908A 2022-07-22 2023-07-21 Compuestos cíclicos y métodos de uso de estos AR129979A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US202263391548P 2022-07-22 2022-07-22

Publications (1)

Publication Number Publication Date
AR129979A1 true AR129979A1 (es) 2024-10-16

Family

ID=89618536

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP230101908A AR129979A1 (es) 2022-07-22 2023-07-21 Compuestos cíclicos y métodos de uso de estos

Country Status (12)

Country Link
EP (1) EP4558505A2 (es)
JP (1) JP2025524002A (es)
KR (1) KR20250039465A (es)
CN (1) CN119923398A (es)
AR (1) AR129979A1 (es)
AU (1) AU2023312000A1 (es)
CA (1) CA3262000A1 (es)
CL (1) CL2025000161A1 (es)
IL (1) IL318375A (es)
MX (1) MX2025000635A (es)
TW (1) TW202417445A (es)
WO (1) WO2024020534A2 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117120442A (zh) * 2021-01-26 2023-11-24 薛定谔公司 用于治疗癌症、自身免疫性病症和炎性病症的三环化合物
WO2025059027A1 (en) * 2023-09-11 2025-03-20 Schrödinger, Inc. Cyclopenta[e]pyrazolo[1,5-a]pyrimidine derivatives as malt1 inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1349834A2 (en) * 2000-12-18 2003-10-08 Eli Lilly And Company Cycloalkyfused [g]-indole compounds as spla2-inhibitors in the treatment of inflammatory diseases
US20240018157A1 (en) * 2019-12-27 2024-01-18 Schrödinger, Inc. Cyclic compounds and methods of using same
EP4284804A1 (en) * 2021-01-26 2023-12-06 Schrödinger, Inc. Tricyclic compounds useful in the treatment of cancer, autoimmune and inflammatory disorders

Also Published As

Publication number Publication date
CA3262000A1 (en) 2024-01-25
KR20250039465A (ko) 2025-03-20
CL2025000161A1 (es) 2025-05-16
TW202417445A (zh) 2024-05-01
WO2024020534A2 (en) 2024-01-25
CN119923398A (zh) 2025-05-02
EP4558505A2 (en) 2025-05-28
IL318375A (en) 2025-03-01
WO2024020534A3 (en) 2024-03-07
MX2025000635A (es) 2025-04-02
AU2023312000A1 (en) 2025-02-20
JP2025524002A (ja) 2025-07-25

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