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AR112908A1 - ANTI-SENSE OLIGONUCLEOTIDES TO MODULATE THE EXPRESSION OF HTRA1 - Google Patents

ANTI-SENSE OLIGONUCLEOTIDES TO MODULATE THE EXPRESSION OF HTRA1

Info

Publication number
AR112908A1
AR112908A1 ARP180101419A ARP180101419A AR112908A1 AR 112908 A1 AR112908 A1 AR 112908A1 AR P180101419 A ARP180101419 A AR P180101419A AR P180101419 A ARP180101419 A AR P180101419A AR 112908 A1 AR112908 A1 AR 112908A1
Authority
AR
Argentina
Prior art keywords
htra1
expression
modulate
sense oligonucleotides
modulation
Prior art date
Application number
ARP180101419A
Other languages
Spanish (es)
Inventor
Andreas Dieckmann
Lykke Pedersen
Sindri Traustason
Susanne Kammler
Roberto Iacone
Marco Berrera
Heidi Rye Hudlebusch
Sren Ottosen
Peter Hagedorn
Snchez Rubn Alvarez
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of AR112908A1 publication Critical patent/AR112908A1/en

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Abstract

La presente se refiere a oligonucleótidos (oligómeros) antisentido que son complementarios a HTRA1, que conducen a la modulación de la expresión de HTRA1. La modulación de la expresión de HTRA1 resulta beneficiosa para un abanico de trastornos médicos, tales como la degeneración macular, por ejemplo, la degeneración macular asociada a la edad.This refers to antisense oligonucleotides (oligomers) that are complementary to HTRA1, leading to modulation of HTRA1 expression. Modulation of HTRA1 expression is beneficial for a range of medical disorders, such as macular degeneration, for example age-related macular degeneration.

ARP180101419A 2017-06-01 2018-05-30 ANTI-SENSE OLIGONUCLEOTIDES TO MODULATE THE EXPRESSION OF HTRA1 AR112908A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP17173964 2017-06-01

Publications (1)

Publication Number Publication Date
AR112908A1 true AR112908A1 (en) 2020-01-08

Family

ID=67436465

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP180101419A AR112908A1 (en) 2017-06-01 2018-05-30 ANTI-SENSE OLIGONUCLEOTIDES TO MODULATE THE EXPRESSION OF HTRA1

Country Status (1)

Country Link
AR (1) AR112908A1 (en)

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