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AR112286A2 - Sistema polimérico de lágrimas artificiales - Google Patents

Sistema polimérico de lágrimas artificiales

Info

Publication number
AR112286A2
AR112286A2 ARP180102103A AR112286A2 AR 112286 A2 AR112286 A2 AR 112286A2 AR P180102103 A ARP180102103 A AR P180102103A AR 112286 A2 AR112286 A2 AR 112286A2
Authority
AR
Argentina
Prior art keywords
formulations
artificial tears
polymeric system
borate
hydroxypropylguar
Prior art date
Application number
Other languages
English (en)
Original Assignee
Alcon Res Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40886688&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR112286(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alcon Res Ltd filed Critical Alcon Res Ltd
Publication of AR112286A2 publication Critical patent/AR112286A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/08—Ethers or acetals acyclic, e.g. paraformaldehyde
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/736—Glucomannans or galactomannans, e.g. locust bean gum, guar gum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se divulgan formulaciones de lagrimas artificiales y formulaciones oftálmicas adecuadas para el suministro de fármacos. Las formulaciones comprenden galactomananos tales como guar o hidroxipropilguar y una fuente de borato tal como ácido bórico. Las formulaciones también comprenden un cis-diol tal como sorbitol que interfiere en la formación de enlaces cruzados de galactomanano y borato. Opcionalmente, las formulaciones están sustancialmente libres de cationes divalentes.
ARP180102103 2008-04-26 2018-07-26 Sistema polimérico de lágrimas artificiales AR112286A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4817508P 2008-04-26 2008-04-26

Publications (1)

Publication Number Publication Date
AR112286A2 true AR112286A2 (es) 2019-10-09

Family

ID=40886688

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP090101464A AR071834A1 (es) 2008-04-26 2009-04-24 Sistema polimerico de lagrimas artificiales
ARP180102103 AR112286A2 (es) 2008-04-26 2018-07-26 Sistema polimérico de lágrimas artificiales

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ARP090101464A AR071834A1 (es) 2008-04-26 2009-04-24 Sistema polimerico de lagrimas artificiales

Country Status (17)

Country Link
US (3) US20090270345A1 (es)
EP (1) EP2278954B1 (es)
JP (1) JP5659149B2 (es)
KR (1) KR101592872B1 (es)
CN (1) CN102046150B (es)
AR (2) AR071834A1 (es)
AU (1) AU2009240488B2 (es)
BR (1) BRPI0910717A2 (es)
CA (1) CA2722508C (es)
CL (1) CL2009000985A1 (es)
ES (1) ES2818619T3 (es)
MX (1) MX2010011736A (es)
NZ (1) NZ589323A (es)
TW (1) TWI526213B (es)
UY (1) UY31785A1 (es)
WO (1) WO2009132294A1 (es)
ZA (1) ZA201007644B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7220431B2 (en) * 2002-11-27 2007-05-22 Regents Of The University Of Minnesota Methods and compositions for applying pharmacologic agents to the ear
US20050137166A1 (en) * 2003-12-19 2005-06-23 Alcon, Inc. Use of cooling agents to relieve mild ocular irritation and enhance comfort
ES2818619T3 (es) * 2008-04-26 2021-04-13 Alcon Inc Sistema de lagrima artificial polimérico
TWI547522B (zh) 2009-07-07 2016-09-01 愛爾康研究有限公司 環氧乙烷環氧丁烷嵌段共聚物組成物
TWI478730B (zh) * 2009-12-03 2015-04-01 Alcon Res Ltd 眼科乳劑
SI2965749T1 (sl) * 2009-12-03 2018-09-28 Novartis Ag Suspenzije nanodelcev, ki vsebujejo karboksivinilni polimer
SG10201804305SA (en) * 2010-05-05 2018-06-28 Alcon Res Ltd Stabilized ophthalmic galactomannan formulations
UA113434C2 (uk) * 2012-05-04 2017-01-25 Алкон Рісерч, Лтд. Офтальмологічна композиція з поліпшеним захистом від зневоднювання й утриманням
US20130344619A1 (en) 2012-06-21 2013-12-26 Lightship Medical Limited Glucose sensor
US11730699B2 (en) 2018-02-21 2023-08-22 Alcon Inc. Lipid-based ophthalmic emulsion
TWI884130B (zh) 2018-02-21 2025-05-21 瑞士商愛爾康公司 基於脂質的眼用乳劑
JP6705495B1 (ja) * 2018-12-26 2020-06-03 株式会社Ｊｖｃケンウッド 車両用記録制御装置、車両用記録装置、車両用記録制御方法およびプログラム
US12329763B2 (en) * 2019-03-04 2025-06-17 Guangzhou Ocusun Ophthalmic Biotechnology Co., Ltd. Composition of lanosterol prodrug compound, preparation method therefor and use thereof
TWI757773B (zh) * 2019-06-28 2022-03-11 瑞士商愛爾康公司 眼用組成物
WO2021053586A1 (en) 2019-09-18 2021-03-25 Alcon Inc. Wet-packed soft hydrogel ocular inserts
CN114191378A (zh) * 2021-11-23 2022-03-18 温州医科大学附属眼视光医院 一种地夸磷索缓释凝胶及其制备方法与应用
US20250276007A1 (en) 2024-03-04 2025-09-04 Alcon Inc. Carbamoylphenylboronic acid-containing acrylic monomers and uses thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4136173A (en) * 1977-01-31 1979-01-23 American Home Products Corp. Mixed xanthan gum and locust beam gum therapeutic compositions
GB1593954A (en) * 1977-01-31 1981-07-22 American Home Prod Xanthan gum or locust bean gum topical therapeutic compositions
US5505953A (en) * 1992-05-06 1996-04-09 Alcon Laboratories, Inc. Use of borate-polyol complexes in ophthalmic compositions
PT999854E (pt) * 1997-07-29 2003-12-31 Alcon Mfg Ltd Sistemas viscoelasticos comutaveis contendo polimeros de galactomanano e borato
WO1999006023A1 (en) * 1997-07-29 1999-02-11 Alcon Laboratories, Inc. Ophthalmic compositions containing galactomannan polymers and borate
IT1298758B1 (it) * 1998-03-19 2000-02-02 Angelini Ricerche Spa Soluzione umettante e lubrificante per uso oftalmico
TWI336257B (en) * 2003-06-13 2011-01-21 Alcon Inc Ophthalmic compositions containing a synergistic combination of three polymers
US20050129771A1 (en) * 2003-12-11 2005-06-16 Alcon, Inc. Ophthalmic compositions containing a polysaccharide/borate gelling system
DE102006031500A1 (de) 2006-07-06 2008-04-17 Henkel Kgaa O/W-Emulsion
WO2008036855A2 (en) * 2006-09-21 2008-03-27 Alcon Research, Ltd. Self-preserved aqueous pharmaceutical compositions
US9096819B2 (en) * 2008-01-31 2015-08-04 Bausch & Lomb Incorporated Ophthalmic compositions with an amphoteric surfactant and an anionic biopolymer
US8119112B2 (en) * 2008-01-31 2012-02-21 Bausch & Lomb Incorporated Ophthalmic compositions with an amphoteric surfactant and hyaluronic acid
ES2818619T3 (es) * 2008-04-26 2021-04-13 Alcon Inc Sistema de lagrima artificial polimérico
SG10201804305SA (en) * 2010-05-05 2018-06-28 Alcon Res Ltd Stabilized ophthalmic galactomannan formulations

Also Published As

Publication number Publication date
AR071834A1 (es) 2010-07-21
KR101592872B1 (ko) 2016-02-12
ES2818619T3 (es) 2021-04-13
US8685945B2 (en) 2014-04-01
TWI526213B (zh) 2016-03-21
AU2009240488B2 (en) 2013-02-21
BRPI0910717A2 (pt) 2015-09-29
UY31785A1 (es) 2009-08-03
NZ589323A (en) 2012-04-27
EP2278954B1 (en) 2020-08-26
US20140161760A1 (en) 2014-06-12
US20090270345A1 (en) 2009-10-29
US20120070402A1 (en) 2012-03-22
MX2010011736A (es) 2011-01-21
JP5659149B2 (ja) 2015-01-28
WO2009132294A1 (en) 2009-10-29
AU2009240488A1 (en) 2009-10-29
CN102046150B (zh) 2013-07-24
CN102046150A (zh) 2011-05-04
KR20110007228A (ko) 2011-01-21
JP2011518842A (ja) 2011-06-30
CA2722508C (en) 2016-08-16
CA2722508A1 (en) 2009-10-29
CL2009000985A1 (es) 2010-01-15
EP2278954A1 (en) 2011-02-02
TW200948367A (en) 2009-12-01
ZA201007644B (en) 2011-12-28
US9259472B2 (en) 2016-02-16

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