AR112217A1 - A COMBINATION OF AN INHIBITOR OF MPS1 AND A COMPOUND TAXAN, USES AND PHARMACEUTICAL COMPOSITIONS OF THE latter - Google Patents
A COMBINATION OF AN INHIBITOR OF MPS1 AND A COMPOUND TAXAN, USES AND PHARMACEUTICAL COMPOSITIONS OF THE latterInfo
- Publication number
- AR112217A1 AR112217A1 ARP180101809A AR112217A1 AR 112217 A1 AR112217 A1 AR 112217A1 AR P180101809 A ARP180101809 A AR P180101809A AR 112217 A1 AR112217 A1 AR 112217A1
- Authority
- AR
- Argentina
- Prior art keywords
- combination
- mps1
- inhibitor
- compound
- taxan
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 102100022681 40S ribosomal protein S27 Human genes 0.000 abstract 1
- 101000678466 Homo sapiens 40S ribosomal protein S27 Proteins 0.000 abstract 1
- 101001019502 Homo sapiens Alpha-L-iduronidase Proteins 0.000 abstract 1
- 101000659223 Homo sapiens Dual specificity protein kinase TTK Proteins 0.000 abstract 1
- 229940123237 Taxane Drugs 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- -1 taxane compound Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Una combinación que comprende un inhibidor de MPS1 de fórmula (1) o una de sus sales de adición con un ácido o base farmacéuticamente aceptable, y un compuesto taxano, y composiciones y usos de esta.A combination comprising an MPS1 inhibitor of formula (1) or an addition salts thereof with a pharmaceutically acceptable acid or base, and a taxane compound, and compositions and uses thereof.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17305847 | 2017-06-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR112217A1 true AR112217A1 (en) | 2019-10-02 |
Family
ID=59313173
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP180101809 AR112217A1 (en) | 2017-06-30 | 2018-06-29 | A COMBINATION OF AN INHIBITOR OF MPS1 AND A COMPOUND TAXAN, USES AND PHARMACEUTICAL COMPOSITIONS OF THE latter |
Country Status (2)
| Country | Link |
|---|---|
| AR (1) | AR112217A1 (en) |
| WO (1) | WO2019002542A1 (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2022414970A1 (en) * | 2021-12-15 | 2024-06-27 | Sillajen, Inc. | Pharmaceutical compositions comprising modified beta-cyclodextrins |
| KR20240107189A (en) * | 2021-12-15 | 2024-07-08 | 신라젠(주) | Pharmaceutical combinations for use in the treatment of neoplastic diseases |
| CA3241111A1 (en) * | 2021-12-15 | 2023-06-22 | Heidi Lane | Methods of treating neoplastic diseases |
| MX2024010802A (en) * | 2022-03-04 | 2024-09-11 | Sillajen Inc | Pharmaceutical combinations for use in the treatment of neoplastic diseases. |
| EP4506015A1 (en) | 2023-08-09 | 2025-02-12 | Nerviano Medical Sciences S.r.l. | Combination of a mps1 inhibitor and an antibody drug conjugate |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI2303891T1 (en) * | 2008-06-26 | 2016-06-30 | Les Laboratoires Servier | Pyrazolo-quinazolines as protein kinase activity modulators |
| TW201437211A (en) * | 2013-03-01 | 2014-10-01 | Bayer Pharma AG | Substituted imidazolium |
-
2018
- 2018-06-29 AR ARP180101809 patent/AR112217A1/en unknown
- 2018-06-29 WO PCT/EP2018/067572 patent/WO2019002542A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2019002542A1 (en) | 2019-01-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |