AR111420A1 - Derivados de heterociclos bicíclicos condensados como plaguicidas - Google Patents
Derivados de heterociclos bicíclicos condensados como plaguicidasInfo
- Publication number
- AR111420A1 AR111420A1 ARP180101050A ARP180101050A AR111420A1 AR 111420 A1 AR111420 A1 AR 111420A1 AR P180101050 A ARP180101050 A AR P180101050A AR P180101050 A ARP180101050 A AR P180101050A AR 111420 A1 AR111420 A1 AR 111420A1
- Authority
- AR
- Argentina
- Prior art keywords
- alkyl
- alkoxy
- halogen
- carbonyl
- cycloalkyl
- Prior art date
Links
- 239000000575 pesticide Substances 0.000 title 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 45
- 229910052736 halogen Inorganic materials 0.000 abstract 29
- 125000000217 alkyl group Chemical group 0.000 abstract 27
- 150000002367 halogens Chemical class 0.000 abstract 25
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 10
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 9
- -1 cyano, nitro, hydroxy, amino, carboxy, carbamoyl Chemical group 0.000 abstract 9
- 229910052760 oxygen Inorganic materials 0.000 abstract 9
- 239000001301 oxygen Substances 0.000 abstract 9
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 8
- 229910052757 nitrogen Inorganic materials 0.000 abstract 8
- 229910052717 sulfur Inorganic materials 0.000 abstract 8
- 239000011593 sulfur Substances 0.000 abstract 8
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 6
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 abstract 5
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 abstract 5
- 125000003601 C2-C6 alkynyl group Chemical group 0.000 abstract 5
- 125000006642 (C1-C6) cyanoalkyl group Chemical group 0.000 abstract 4
- 125000006577 C1-C6 hydroxyalkyl group Chemical group 0.000 abstract 4
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 4
- 125000004397 aminosulfonyl group Chemical group NS(=O)(=O)* 0.000 abstract 4
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 4
- 229910052799 carbon Inorganic materials 0.000 abstract 4
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 4
- 125000001188 haloalkyl group Chemical group 0.000 abstract 4
- 125000005347 halocycloalkyl group Chemical group 0.000 abstract 4
- 125000001072 heteroaryl group Chemical group 0.000 abstract 4
- 229910052739 hydrogen Chemical group 0.000 abstract 4
- 239000001257 hydrogen Chemical group 0.000 abstract 4
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 4
- 125000001424 substituent group Chemical group 0.000 abstract 4
- 125000004737 (C1-C6) haloalkoxy group Chemical group 0.000 abstract 3
- 125000000171 (C1-C6) haloalkyl group Chemical group 0.000 abstract 3
- 125000004682 aminothiocarbonyl group Chemical group NC(=S)* 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 3
- 125000000262 haloalkenyl group Chemical group 0.000 abstract 3
- 150000002431 hydrogen Chemical class 0.000 abstract 3
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000304 alkynyl group Chemical group 0.000 abstract 2
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 2
- 125000005159 cyanoalkoxy group Chemical group 0.000 abstract 2
- 125000004122 cyclic group Chemical group 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000004767 (C1-C4) haloalkoxy group Chemical group 0.000 abstract 1
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- 125000006529 (C3-C6) alkyl group Chemical group 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical group [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- JCXJVPUVTGWSNB-UHFFFAOYSA-N Nitrogen dioxide Chemical compound O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000006615 aromatic heterocyclic group Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000002619 bicyclic group Chemical group 0.000 abstract 1
- 125000001951 carbamoylamino group Chemical group C(N)(=O)N* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 abstract 1
- 125000004438 haloalkoxy group Chemical group 0.000 abstract 1
- 125000000232 haloalkynyl group Chemical group 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- ZMZDMBWJUHKJPS-UHFFFAOYSA-N thiocyanic acid Chemical compound SC#N ZMZDMBWJUHKJPS-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Agronomy & Crop Science (AREA)
- General Health & Medical Sciences (AREA)
- Pest Control & Pesticides (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Reivindicación 1: Compuestos de la fórmula (1), en donde ⁻ ⁻ ⁻ ⁻ ⁻ representa dos enlaces simples o un enlace doble y un enlace simple, en donde, para el caso de que ⁻ ⁻ ⁻ ⁻ ⁻ represente un enlace doble y un enlace simple y así Aa a Ae conformen un anillo aromático, Aa representa nitrógeno o carbono; Ab representa nitrógeno, oxígeno, azufre, N(R⁸) o C(R¹¹); Ac representa nitrógeno, oxígeno, azufre o C(R¹²); Ad representa nitrógeno, oxígeno, azufre, N(R⁸) o C(R¹³); Ae representa nitrógeno o carbono, en donde R⁸ representa alquilo C₁₋₄, ciclopropilo o hidrógeno y en donde como máximo tres de los grupos Aa, Ab, Ac, Ad y Ae pueden representar nitrógeno y como máximo uno de los grupos Ab, Ac y Ad pueden representar oxígeno o como máximo uno de los grupos Ab, Ac y Ad pueden representar azufre o como máximo uno de los grupos Ab y Ad puede representar N(R⁸); o para el caso de que ⁻ ⁻ ⁻ ⁻ ⁻ representen exclusivamente enlaces simples, Aa representa carbono; Ab representa azufre, oxígeno o C(R¹¹)(R¹⁵); Ac representa azufre, oxígeno o C(R¹²)(R¹⁶); y Ad representa azufre, oxígeno o C(R¹³)(R¹⁷); Ae representa carbono, donde como máximo uno de los grupos Aa, Ab, Ac, Ad y Ae puede representar oxígeno o azufre; R¹ representa alquilo C₁₋₆, halógenoalquilo C₁₋₆, cianoalquilo C₁₋₆, hidroxialquilo C₁₋₆, alcoxi C₁₋₆-alquilo C₁₋₆, halógenoalcoxi C₁₋₆-alquilo C₁₋₆, alquenilo C₂₋₆, alquenil C₂₋₆-oxi-alquilo C₁₋₆, halógenoalquenil C₂₋₆-oxi-alquilo C₁₋₆, halógenoalquenilo C₂₋₆, cianoalquenilo C₂₋₆, alquinilo C₂₋₆, alquinil C₂₋₆-oxi-alquilo C₁₋₆, halógenoalquinil C₂₋₆-oxi-alquilo C₁₋₆, halógenoalquinilo C₂₋₆, cianoalquinilo C₂₋₆, cicloalquilo C₃₋₈, cicloalquil C₃₋₈-cicloalquilo C₃₋₈, alquil C₁₋₆-cicloalquilo C₃₋₈, halógenocicloalquilo C₃₋₈, amino, alquil C₁₋₆-amino, di-alquil C₁₋₆-amino, cicloalquil C₃₋₈-amino, alquil C₁₋₆-carbonil-amino, alquil C₁₋₆-tio-alquilo C₁₋₆, halógenoalquil C₁₋₆-tio-alquilo C₁₋₆, alquil C₁₋₆-sulfinil-alquilo C₁₋₆, halógenoalquil C₁₋₆-sulfinil-alquilo C₁₋₆, alquil C₁₋₆-sulfonil-alquilo C₁₋₆, halógenoalquil C₁₋₆-sulfonil-alquilo C₁₋₆, alcoxi C₁₋₆-alquil C₁₋₆-tio-alquilo C₁₋₆, alcoxi C₁₋₆-alquil C₁₋₆-sulfinil-alquilo C₁₋₆, alcoxi C₁₋₆-alquil C₁₋₆-sulfonil-alquilo C₁₋₆, alquil C₁₋₆-carbonil-alquilo C₁₋₆, halógenoalquil C₁₋₆-carbonil-alquilo C₁₋₆, alcoxi C₁₋₆-carbonil-alquilo C₁₋₆, halógenoalcoxi C₁₋₆-carbonil-alquilo C₁₋₆, alquil C₁₋₆-sulfonilamino, aminosulfonil-alquilo C₁₋₆, alquil C₁₋₆-aminosulfonil-alquilo C₁₋₆, di-alquil C₁₋₆-aminosulfonil-alquilo C₁₋₆, o alquilo C₁₋₆, alcoxi C₁₋₆, alquenilo C₂₋₆, alquinilo C₂₋₆, cicloalquilo C₃₋₈ en cada caso opcionalmente mono- o polisustituido, igual o diferente con arilo, hetarilo o heterociclilo, en donde arilo, hetarilo o heterociclilo pueden estar cada uno opcionalmente mono- o polisustituidos, iguales o diferentes con halógeno, ciano, nitro, hidroxi, amino, carboxi, carbamoilo, aminosulfonilo, alquilo C₁₋₆, cicloalquilo C₃₋₆, alcoxi C₁₋₆, halógenoalquilo C₁₋₆, halógenoalcoxi C₁₋₆, alquil C₁₋₆-tio, alquil C₁₋₆-sulfinilo, alquil C₁₋₆-sulfonilo, alquil C₁₋₆-sulfimino, alquil C₁₋₆-sulfimino-alquilo C₁₋₆, alquil C₁₋₆-sulfimino-alquil C₂₋₆-carbonilo, alquil C₁₋₆-sulfoximino, alquil C₁₋₆-sulfoximino-alquilo C₁₋₆, alquil C₁₋₆-sulfoximino-alquil C₂₋₆-carbonilo, alcoxi C₁₋₆-carbonilo, alquil C₁₋₆-carbonilo, trialquil C₃₋₆-sililo o bencilo; R¹¹ R¹², R¹³, R¹⁵, R¹⁶, R¹⁷ representan, de modo independiente entre sí, hidrógeno, ciano, halógeno, nitro, hidroxi, amino, trialquil C₁₋₆-sililo, cicloalquilo C₃₋₈, cicloalquil C₃₋₈-cicloalquilo C₃₋₈, alquil C₁₋₆-cicloalquilo C₃₋₈, halógenocicloalquilo C₃₋₈, alquilo C₁₋₆, halógenoalquilo C₁₋₆, cianoalquilo C₁₋₆, hidroxialquilo C₁₋₆, hidroxicarbonil-alcoxi C₁₋₆, alcoxi C₁₋₆-carbonil-alquilo C₁₋₆, alcoxi C₁₋₆-alquilo C₁₋₆, alquenilo C₂₋₆, halógenoalquenilo C₂₋₆, cianoalquenilo C₂₋₆, alquinilo C₂₋₆, halógenoalquinilo C₂₋₆, cianoalquinilo C₂₋₆, alcoxi C₁₋₆, halógenoalcoxi C₁₋₆, cianoalcoxi C₁₋₆, alcoxi C₁₋₆-carbonil-alcoxi C₁₋₆, alcoxi C₁₋₆-alcoxi C₁₋₆, alquil C₁₋₆-hidroxiimino, alcoxi C₁₋₆-imino, alquil C₁₋₆-alcoxi C₁₋₆-imino, halógenoalquil C₁₋₆-alcoxi C₁₋₆-imino, alquil C₁₋₆-tio, halógenoalquil C₁₋₆-tio, alcoxi C₁₋₆-alquil C₁₋₆-tio, alquil C₁₋₆-tio-alquilo C₁₋₆, alquil C₁₋₆-sulfinilo, halógenoalquil C₁₋₆-sulfinilo, alcoxi C₁₋₆-alquil C₁₋₆-sulfinilo, alquil C₁₋₆-sulfinil-alquilo C₁₋₆, alquil C₁₋₆-sulfonilo, halógenoalquil C₁₋₆-sulfonilo, alcoxi C₁₋₆-alquil C₁₋₆-sulfonilo, alquil C₁₋₆-sulfonil-alquilo C₁₋₆, alquil C₁₋₆-sulfoniloxi, alquil C₁₋₆-carbonilo, alquil C₁₋₆-tiocarbonilo, halógenoalquil C₁₋₆-carbonilo, alquil C₁₋₆-carboniloxi, alcoxi C₁₋₆-carbonilo, halógenoalcoxi C₁₋₆-carbonilo, aminocarbonilo, alquil C₁₋₆-aminocarbonilo, alquil C₁₋₆-aminotiocarbonilo, di-alquil C₁₋₆-aminocarbonilo, di-alquil C₁₋₆-aminotiocarbonilo, alquenil C₂₋₆-aminocarbonilo, di-alquenil C₂₋₆-aminocarbonilo, cicloalquil C₃₋₈-aminocarbonilo, alquil C₁₋₆-sulfonilamino, alquil C₁₋₆-amino, di-alquil C₁₋₆-amino, cicloalquil C₃₋₈-amino, aminosulfonilo, alquil C₁₋₆-aminosulfonilo, di-alquil C₁₋₆-aminosulfonilo, alquil C₁₋₆-sulfoximino, aminotiocarbonilo, alquil C₁₋₆-aminotiocarbonilo, di-alquil C₁₋₆-aminotiocarbonilo, alquil C₁₋₆-carbonilamino (-NHCO-alquilo C₁₋₆), cicloalquil C₃₋₈-carbonilamino, alquil C₁₋₆-carbonil-alquil C₁₋₆)-amino (-N-alquil C₁₋₆-CO-alquilo C₁₋₆), (alcoxi C₁₋₆-carbonil)amino (-NHCOO-alquilo C₁₋₆), (alcoxi C₁₋₆-carbonil)alquil C₁₋₆-amino (-N-alquil C₁₋₆-COO-alquilo C₁₋₆), alquil C₁₋₆-carbamoiloxi (-OCONH-alquilo C₁₋₆), di-alquil C₁₋₆-carbamoiloxi (-OCON-dialquilo C₁₋₆), (N-alquil C₁₋₆)-carbamoil)amino (-NHCONH-alquilo C₁₋₆), (N,N-di-alquil C₁₋₆-carbamoil)amino (-NHCON-dialquilo C₁₋₆), (N-alquil C₁₋₆-carbamoil)alquil C₁₋₆-amino (-N-alquil C₁₋₆-CONH-alquilo C₁₋₆), (N,N-di-alquil C₁₋₆-carbamoil)alquil C₁₋₆-amino (-N-alquil C₁₋₆-CON-dialquilo C₁₋₆), carbamoilamino (-NHCONH₂), (carbamoil)-N-alquil C₁₋₆-amino (-N-alquil C₁₋₆-CONH₂) o representan arilo o hetarilo en cada caso opcionalmente mono- o polisustituido, iguales o diferentes, en donde (en el caso de hetarilo) puede estar contenido opcionalmente al menos un grupo carbonilo y en donde como sustituyentes se tienen en cuenta, en cada caso: ciano, carboxilo, halógeno, nitro, hidroxi, amino, trialquil C₁₋₆-sililo, cicloalquilo C₃₋₈, cicloalquil C₃₋₈-cicloalquilo C₃₋₈, alquil C₁₋₆-cicloalquilo C₃₋₈, halógenocicloalquilo C₃₋₈, alquilo C₁₋₆, halógenoalquilo C₁₋₆, cianoalquilo C₁₋₆, hidroxialquilo C₁₋₆, hidroxicarbonil-alcoxi C₁₋₆, alcoxi C₁₋₆-carbonil-alquilo C₁₋₆, alcoxi C₁₋₆-alquilo C₁₋₆, alquenilo C₂₋₆, halógenoalquenilo C₂₋₆, cianoalquenilo C₂₋₆, alquinilo C₂₋₆, halógenoalquinilo C₂₋₆, cianoalquinilo C₂₋₆, alcoxi C₁₋₆, halógenoalcoxi C₁₋₆, cianoalcoxi C₁₋₆, alcoxi C₁₋₆-carbonil-alcoxi C₁₋₆, alcoxi C₁₋₆-alcoxi C₁₋₆, alquil C₁₋₆-hidroxiimino, alcoxi C₁₋₆-imino, alquil C₁₋₆-alcoxi C₁₋₆-imino, halógenoalquil C₁₋₆-alcoxi C₁₋₆-imino, alquil C₁₋₆-tio, halógenoalquil C₁₋₆-tio, alcoxi C₁₋₆-alquil C₁₋₆-tio, alquil C₁₋₆-tio-alquilo C₁₋₆, alquil C₁₋₆-sulfinilo, halógenoalquil C₁₋₆-sulfinilo, alcoxi C₁₋₆-alquil C₁₋₆-sulfinilo, alquil C₁₋₆-sulfinil-alquilo C₁₋₆, alquil C₁₋₆-sulfonilo, halógenoalquil C₁₋₆-sulfonilo, alcoxi C₁₋₆-alquil C₁₋₆-sulfonilo, alquil C₁₋₆-sulfonil-alquilo C₁₋₆, alquil C₁₋₆-sulfoniloxi, alquil C₁₋₆-carbonilo, halógenoalquil C₁₋₆-carbonilo, alquil C₁₋₆-carboniloxi, alcoxi C₁₋₆-carbonilo, halógenoalcoxi C₁₋₆-carbonilo, aminocarbonilo, alquil C₁₋₆-aminocarbonilo, di-alquil C₁₋₆-aminocarbonilo, alquenil C₂₋₆-aminocarbonilo, di-alquenil C₂₋₆-aminocarbonilo, cicloalquil C₃₋₈-aminocarbonilo, alquil C₁₋₆-sulfonilamino, alquil C₁₋₆-amino, di-alquil C₁₋₆-amino, aminosulfonilo, alquil C₁₋₆-aminosulfonilo, di-alquil C₁₋₆-aminosulfonilo, alquil C₁₋₆-sulfoximino, aminotiocarbonilo, alquil C₁₋₆-aminotiocarbonilo, di-alquil C₁₋₆-aminotiocarbonilo, cicloalquil C₃₋₈-amino o alquil C₁₋₆-carbonilamino, en donde como máximo dos de los radicales R¹¹, R¹², R¹³, R¹⁵, R¹⁶, R¹⁷ representan un sustituyente no igual a hidrógeno, y en el caso de que R¹¹ y R¹⁵, R¹² y R¹⁶ o R¹³ y R¹⁷ sean ambos distintos de hidrógeno, R¹⁵, R¹⁶ y R¹⁷ representan en cada caso, de modo independiente entre sí, sólo ciano, halógeno, cicloalquilo C₃₋₆, cicloalquil C₃₋₆-cicloalquilo C₃₋₆, alquil C₁₋₄-cicloalquilo C₃₋₆, halógenocicloalquilo C₃₋₆, alquilo C₁₋₄, halógenoalquilo C₁₋₄ o cianoalquilo C₁₋₄; o para el caso de que ⁻ ⁻ ⁻ ⁻ ⁻ representen exclusivamente enlaces simples, además, R¹¹ y R¹⁵ y/o R¹³ y R¹⁷ representan juntos en cada caso oxígeno (=O); Q representa un sistema de anillos bicíclicos o tricíclicos fusionados de 8, 9, 10, 11 ó 12 miembros heterocíclico o heteroaromático parcialmente saturado o saturado, en donde puede estar contenido opcionalmente al menos un grupo carbonilo y/o en donde el sistema de anillos está opcionalmente mono- o polisustituido, igual o diferente y en donde los sustituyentes pueden estar seleccionados, de modo independiente entre sí, de ciano, halógeno, nitro, acetilo, hidroxi, amino, SCN, trialquil C₁₋₆-sililo, halógenocicloalquilo C₃₋₈, alquilo C₁₋₆, halógenoalquilo C₁₋₆, cianoalquilo C₁₋₆, hidroxialquilo C₁₋₆, hidroxicarbonil-alcoxi C₁₋₆, alcoxi C₁₋₆-carbonil-alquilo C₁₋₆, alcoxi C₁₋₆-alquilo C₁₋₆, alquenilo C₂₋₆, halógenoalquenilo C₂₋₆, cianoalquenilo C₂₋₆, alquinilo C₂₋₆, alquinil C₂₋₆-oxi-alquilo C₁₋₄, halógenoalquinilo C₂₋₆, cianoalquinilo C₂₋₆, alcoxi C₁₋₆, halógenoalcoxi C₁₋₆, halógenoalcoxi C₁₋₆-alquilo C₁₋₆, alquenil C₂₋₆-oxi-alquilo C₁₋₆, halógenoalquenil C₂₋₆-oxi-alquilo C₁₋₆, cianoalcoxi C₁₋₆, alcoxi C₁₋₆-carbonil-alcoxi C₁₋₆, alcoxi C₁₋₆-alcoxi C₁₋₆, alquil C₁₋₆-hidroxiimino, alcoxi C₁₋₆-imino, alquil C₁₋₆-alcoxi C₁₋₆-imino, halógenoalquil C₁₋₆-alcoxi C₁₋₆-imino, alquil C₁₋₆-tio, halógenoalquil C₁₋₆-tio, alcoxi C₁₋₆-alquil C₁₋₆-tio, alquil C₁₋₆-tio-alquilo C₁₋₆, alquil C₁₋₆-sulfinilo, halógenoalquil C₁₋₆-sulfinilo, alcoxi C₁₋₆-alquil C₁₋₆-sulfinilo, alquil C₁₋₆-sulfinil-alquilo C₁₋₆, alquil C₁₋₆-sulfonilo, halógenoalquil C₁₋₆-sulfonilo, alcoxi C₁₋₆-alquil C₁₋₆-sulfonilo, alquil C₁₋₆-sulfonil-alquilo C₁₋₆, alquil C₁₋₆-sulfoniloxi, alquil C₁₋₆-carbonilo, alquil C₁₋₆-carbonil-alquilo C₁₋₆, alquil C₁₋₆-tiocarbonilo, halógenoalquil C₁₋₆-carbonilo, alquil C₁₋₆-carboniloxi, alcoxi C₁₋₆-carbonilo, halógenoalcoxi C₁₋₆-carbonilo, aminocarbonilo, alquil C₁₋₆-aminocarbonilo, alquil C₁₋₆-aminotiocarbonilo, di-alquil C₁₋₆-aminocarbonilo, di-alquil C₁₋₆-aminotiocarbonilo, alquenil C₂₋₆-aminocarbonilo, di-alquenil C₂₋₆-aminocarbonilo, cicloalquil C₃₋₈-aminocarbonilo, alquil C₁₋₆-sulfonilamino, alquil C₁₋₆-amino, di-alquil C₁₋₆-amino, aminosulfonilo, alquil C₁₋₆-aminosulfonilo, di-alquil C₁₋₆-aminosulfonilo, alquil C₁₋₆-sulfoximino, aminotiocarbonilo, alquil C₁₋₆-aminotiocarbonilo, di-alquil C₁₋₆-aminotiocarbonilo, cicloalquil C₃₋₈-amino, NHCO-alquilo C₁₋₆ (alquil C₁₋₆-carbonilamino) o cicloalquilo C₃₋₈, cicloalquil C₃₋₈-cicloalquilo C₃₋₈ o alquil C₁₋₄-cicloalquilo C₃₋₈ opcionalmente monosustituido por ciano, o en donde los sustituyentes pueden estar seleccionados, de modo independiente entre sí, de fenilo o un anillo heteroaromático de 5 ó 6 miembros, en donde fenilo o el anillo pueden estar opcionalmente mono- o polisustituidos, iguales o diferentes, con alquilo C₁₋₆, alquenilo C₂₋₆, alquinilo C₂₋₆, cicloalquilo C₃₋₆, haloalquilo C₁₋₆, haloalquenilo C₂₋₆, haloalquinilo C₂₋₆, halocicloalquilo C₃₋₆, halógeno, CN, NO₂, alcoxi C₁₋₄, haloalcoxi C₁₋₄; y n representa 0, 1 ó 2.
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2018
- 2018-04-17 MX MX2019012728A patent/MX2019012728A/es unknown
- 2018-04-17 ES ES18718433T patent/ES2923376T3/es active Active
- 2018-04-17 CN CN201880027004.5A patent/CN110582503B/zh active Active
- 2018-04-17 EP EP18718433.8A patent/EP3615540B1/de active Active
- 2018-04-17 US US16/605,815 patent/US20200128830A1/en not_active Abandoned
- 2018-04-17 AU AU2018257372A patent/AU2018257372B2/en not_active Ceased
- 2018-04-17 BR BR112019022273-1A patent/BR112019022273B1/pt active IP Right Grant
- 2018-04-17 WO PCT/EP2018/059727 patent/WO2018197257A1/de not_active Ceased
- 2018-04-17 JP JP2019557364A patent/JP7119001B2/ja active Active
- 2018-04-17 KR KR1020197034062A patent/KR102537983B1/ko active Active
- 2018-04-20 TW TW107113482A patent/TW201839002A/zh unknown
- 2018-04-24 AR ARP180101050A patent/AR111420A1/es not_active Application Discontinuation
- 2018-04-24 UY UY0001037696A patent/UY37696A/es not_active Application Discontinuation
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2019
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- 2019-10-24 CO CONC2019/0011754A patent/CO2019011754A2/es unknown
- 2019-10-24 CL CL2019003060A patent/CL2019003060A1/es unknown
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| Publication number | Publication date |
|---|---|
| UY37696A (es) | 2018-11-30 |
| CN110582503A (zh) | 2019-12-17 |
| KR20190141202A (ko) | 2019-12-23 |
| BR112019022273A2 (pt) | 2020-06-16 |
| ES2923376T3 (es) | 2022-09-27 |
| KR102537983B1 (ko) | 2023-05-31 |
| CO2019011754A2 (es) | 2020-01-17 |
| JP2020517656A (ja) | 2020-06-18 |
| EP3615540B1 (de) | 2022-04-27 |
| AU2018257372A1 (en) | 2019-11-07 |
| US20200128830A1 (en) | 2020-04-30 |
| TW201839002A (zh) | 2018-11-01 |
| JP7119001B2 (ja) | 2022-08-16 |
| AU2018257372B2 (en) | 2022-06-02 |
| CN110582503B (zh) | 2022-05-31 |
| EP3615540A1 (de) | 2020-03-04 |
| WO2018197257A1 (de) | 2018-11-01 |
| BR112019022273B1 (pt) | 2023-04-11 |
| PH12019502404A1 (en) | 2021-01-25 |
| MX2019012728A (es) | 2020-01-23 |
| CL2019003060A1 (es) | 2020-04-03 |
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