AR111282A1 - Inhibidores de cdpk1 ii, composiciones y métodos relacionados con los mismos - Google Patents
Inhibidores de cdpk1 ii, composiciones y métodos relacionados con los mismosInfo
- Publication number
- AR111282A1 AR111282A1 ARP180100606A ARP180100606A AR111282A1 AR 111282 A1 AR111282 A1 AR 111282A1 AR P180100606 A ARP180100606 A AR P180100606A AR P180100606 A ARP180100606 A AR P180100606A AR 111282 A1 AR111282 A1 AR 111282A1
- Authority
- AR
- Argentina
- Prior art keywords
- cdpk1
- inhibitors
- compositions
- same
- methods related
- Prior art date
Links
- 101000908196 Oryza sativa subsp. japonica Calcium-dependent protein kinase 23 Proteins 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 2
- 125000003161 (C1-C6) alkylene group Chemical group 0.000 abstract 1
- 125000000171 (C1-C6) haloalkyl group Chemical group 0.000 abstract 1
- 125000001313 C5-C10 heteroaryl group Chemical group 0.000 abstract 1
- 125000000041 C6-C10 aryl group Chemical group 0.000 abstract 1
- 125000004450 alkenylene group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Reivindicación 1: Un compuesto con la estructura de fórmula (1), o una sal aceptable farmacéutico del mismo, en la que: X es R⁶, O, S, (NR⁴), OR⁶, SR⁶, o (NR⁴)R⁶; Y es N o CH; R¹ es arilo C₆₋₁₀ o heteroarilo de 5 - 10 miembros; R² es cicloalquilo C₃₋₆; R³ es H, alquilo C₁₋₆, haloalquilo C₁₋₆, cicloalquilo C₃₋₆; R⁴ es H o alquilo C₁₋₆; y R⁶ es alquileno C₁₋₆ o alquenileno C₁₋₆.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762471795P | 2017-03-15 | 2017-03-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR111282A1 true AR111282A1 (es) | 2019-06-26 |
Family
ID=63522614
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP180100606A AR111282A1 (es) | 2017-03-15 | 2018-03-15 | Inhibidores de cdpk1 ii, composiciones y métodos relacionados con los mismos |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20210115047A1 (es) |
| EP (1) | EP3596082A4 (es) |
| AR (1) | AR111282A1 (es) |
| TW (1) | TW201837040A (es) |
| WO (1) | WO2018170236A1 (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019036001A1 (en) * | 2017-08-17 | 2019-02-21 | Vyera Pharmaceuticals, LLC | CDPK1 INHIBITOR, COMPOSITIONS AND RELATED METHODS |
| EP3853230A4 (en) * | 2018-09-19 | 2022-07-06 | Vyera Pharmaceuticals, LLC | CDPK1 INHIBITORS, COMPOSITIONS AND METHODS THEREFOR |
| CN111592557A (zh) * | 2020-05-09 | 2020-08-28 | 河北合佳医药科技集团股份有限公司 | 一种7-氨基-3-乙烯基头孢烷酸的一步法环保制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1831225A2 (en) * | 2004-11-19 | 2007-09-12 | The Regents of the University of California | Anti-inflammatory pyrazolopyrimidines |
| EP2217239A2 (en) * | 2007-11-07 | 2010-08-18 | Foldrx Pharmaceuticals, Inc. | Modulation of protein trafficking |
| JP5819195B2 (ja) * | 2008-10-16 | 2015-11-18 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 融合環ヘテロアリールキナーゼ阻害剤 |
| US9765037B2 (en) * | 2010-01-28 | 2017-09-19 | University Of Washington Through Its Center For Commercialization | Compositions and methods for treating toxoplasmosis, cryptosporidiosis, and other apicomplexan protozoan related diseases |
| WO2011153553A2 (en) * | 2010-06-04 | 2011-12-08 | The Regents Of The University Of California | Methods and compositions for kinase inhibition |
| US8642606B2 (en) * | 2010-09-29 | 2014-02-04 | Plexxikon Inc. | ZAP-70 active compounds |
| CA2841080A1 (en) * | 2011-07-13 | 2013-01-17 | Pharmacyclics, Inc. | Inhibitors of bruton's tyrosine kinase |
-
2018
- 2018-03-14 TW TW107108668A patent/TW201837040A/zh unknown
- 2018-03-15 WO PCT/US2018/022595 patent/WO2018170236A1/en not_active Ceased
- 2018-03-15 AR ARP180100606A patent/AR111282A1/es unknown
- 2018-03-15 US US16/494,052 patent/US20210115047A1/en not_active Abandoned
- 2018-03-15 EP EP18767756.2A patent/EP3596082A4/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| WO2018170236A9 (en) | 2019-01-17 |
| US20210115047A1 (en) | 2021-04-22 |
| WO2018170236A1 (en) | 2018-09-20 |
| EP3596082A4 (en) | 2020-12-16 |
| EP3596082A1 (en) | 2020-01-22 |
| TW201837040A (zh) | 2018-10-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |