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Application filed by Idenix Pharmaceuticals LlcfiledCriticalIdenix Pharmaceuticals Llc
Publication of AR111227A2publicationCriticalpatent/AR111227A2/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
Compuestos y composiciones para el tratamiento de enfermedad hepática y condiciones patológicas, incluyendo infecciones por HCV. Se revelan compuestos derivados de nucleósidos, de fórmula (1), y composiciones que los contienen que se pueden administrar ya sea solos o en combinación con otros agentes antivirales.Compounds and compositions for the treatment of liver disease and pathological conditions, including HCV infections. Nucleoside-derived compounds of formula (1) and compositions containing them that can be administered alone or in combination with other antiviral agents are disclosed.
ARP180100500A2012-05-222018-03-02
D-AMINO ACIDS COMPOUNDS FOR HEPATIC DISEASE
AR111227A2
(en)
Compounds derived from 5-fluoro-2'-deoxyuridine phosphoramidate; preparation procedure; pharmaceutical composition that includes them; its use in the treatment or prophylaxis of cancer.
Compounds derived from 2-oxo-piperidine and 1,1-dioxide-thiazine, mdm2 inhibitors; pharmaceutical composition that includes them; and its use for the treatment of cancer.
Compounds derived from 5-alkynyl-pyrimidines, kinase inhibitors; pharmaceutical compositions containing them; and its use for the treatment and / or prevention of cancer, infections, inflammatory and autoimmune diseases.
Compounds derived from aryl quinoline; obtaining process; pharmaceutical composition that includes them and use in the treatment or prophylaxis of type 2 diabetes, atherosclerosis, cancer, among other diseases.
Compounds derived from substituted 4,5-dihydro-1h-pyrazol (4,3-g) benzothiazole; pharmaceutical composition; Useful for the treatment and prevention of cancer, infections, inflammatory and autoimmune diseases, among others.
Thiophene 2,3,5 trisubstituted derivatives; pharmaceutical composition; pharmaceutical combination; and its use for the treatment of a disorder or disease in a subject caused or associated with a HCV infection, such as liver cirrhosis, hepatocellular carcinoma, among others.