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AR118715A1 - Preparación de pirazoles sustituidos y su uso como precursores de antranilamidas - Google Patents

Preparación de pirazoles sustituidos y su uso como precursores de antranilamidas

Info

Publication number
AR118715A1
AR118715A1 ARP200101086A ARP200101086A AR118715A1 AR 118715 A1 AR118715 A1 AR 118715A1 AR P200101086 A ARP200101086 A AR P200101086A AR P200101086 A ARP200101086 A AR P200101086A AR 118715 A1 AR118715 A1 AR 118715A1
Authority
AR
Argentina
Prior art keywords
formula
compound
preparation
precursors
anthranilamides
Prior art date
Application number
ARP200101086A
Other languages
English (en)
Inventor
Avihai Yacovan
Nahum Itsik Bar
Jie Li
Thomas Zell
Original Assignee
Adama Makhteshim Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adama Makhteshim Ltd filed Critical Adama Makhteshim Ltd
Publication of AR118715A1 publication Critical patent/AR118715A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/16—Halogen atoms or nitro radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Se divulga un método para la preparación de un derivado de pirazol-3-bromo-5-metil-1-H-pirazon-N-2-cloropiridina (compuesto de fórmula (1)) mediante reaccionar un compuesto de fórmula (2) con piridina sustituido con halógeno opcionalmente en la presencia de solvente base y orgánico o por descarboxilación de ácido pirazol carboxílico de fórmula (8) en la presencia de ácido. Además, se proporciona un método de preparación de precursores sintéticos de fórmula (2), fórmula (3), fórmula (4), fórmula (5), fórmula (8), y un método para preparar un compuesto de fórmula (6) que comprende reaccionar un compuesto de fórmula (1) con un oxidante opcionalmente en presencia de un catalizador. También se divulga un compuesto de fórmula (1) como precursor sintético útil para la preparación de una antranilamida de fórmula (7).
ARP200101086A 2019-04-19 2020-04-17 Preparación de pirazoles sustituidos y su uso como precursores de antranilamidas AR118715A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201910317694.4A CN111825653A (zh) 2019-04-19 2019-04-19 取代吡唑类化合物的制备及其作为邻氨基苯甲酰胺前体的用途

Publications (1)

Publication Number Publication Date
AR118715A1 true AR118715A1 (es) 2021-10-27

Family

ID=70554149

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP200101086A AR118715A1 (es) 2019-04-19 2020-04-17 Preparación de pirazoles sustituidos y su uso como precursores de antranilamidas

Country Status (12)

Country Link
US (1) US12459913B2 (es)
EP (1) EP3956314A1 (es)
JP (1) JP7744242B2 (es)
KR (1) KR20250044809A (es)
CN (2) CN111825653A (es)
AR (1) AR118715A1 (es)
AU (2) AU2020257633A1 (es)
BR (1) BR112021020840A2 (es)
CO (1) CO2021013925A2 (es)
IL (1) IL287357B1 (es)
MX (1) MX2021012606A (es)
WO (1) WO2020212991A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220396560A1 (en) * 2019-10-18 2022-12-15 Fmc Corporation Methods for the preparation of 5-bromo-2-(3-chloro-pyridin-2-yl)-2h-pyrazole-3-carboxylic acid
JP2024532152A (ja) 2021-08-19 2024-09-05 シンジェンタ クロップ プロテクション アクチェンゲゼルシャフト ジアミド抵抗性有害生物の防除方法及びそのための化合物

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1261124B (de) 1961-09-22 1968-02-15 Hoechst Ag Verfahren zur Herstellung von Pyrazolen
IL73419A (en) 1983-11-07 1988-02-29 Lilly Co Eli 1h-pyrazole-4-(thio)carboxamide derivatives,their preparation and herbicidal compositions containing them
DE3808896A1 (de) 1988-03-17 1989-09-28 Hoechst Ag Pflanzenschuetzende mittel auf basis von pyrazolcarbonsaeurederivaten
US5907041A (en) 1997-03-12 1999-05-25 Rhone-Poulenc Inc. Process for preparing pyrazole derivatives
MY138097A (en) * 2000-03-22 2009-04-30 Du Pont Insecticidal anthranilamides
TWI327566B (en) 2001-08-13 2010-07-21 Du Pont Novel substituted ihydro 3-halo-1h-pyrazole-5-carboxylates,their preparation and use
AR036872A1 (es) 2001-08-13 2004-10-13 Du Pont Compuesto de antranilamida, composicion que lo comprende y metodo para controlar una plaga de invertebrados
TWI325302B (en) * 2001-08-13 2010-06-01 Du Pont Benzoxazinone compounds
CN1865258A (zh) 2001-08-15 2006-11-22 纳幕尔杜邦公司 用于控制无脊椎害虫的邻位取代的芳基酰胺化合物
TWI326283B (en) 2002-07-31 2010-06-21 Du Pont Method for preparing fused oxazinones
TWI363756B (en) * 2004-12-07 2012-05-11 Du Pont Method for preparing n-phenylpyrazole-1-carboxamides
ES2911293T3 (es) * 2014-11-21 2022-05-18 Akarna Therapeutics Ltd Compuestos bicíclicos fusionados para el tratamiento de enfermedades
CN104844567B (zh) * 2015-04-23 2017-03-29 暨南大学 一种中间体1‑(3‑氯‑2‑吡啶基)‑3‑溴‑1h‑5‑吡唑甲酸的合成方法
CA3025007A1 (en) * 2016-05-25 2017-11-30 Akarna Therapeutics, Ltd. Combination therapies with farnesoid x receptor (fxr) modulators
WO2018064119A1 (en) * 2016-09-28 2018-04-05 Blade Therapeutics, Inc. Calpain modulators and therapeutic uses thereof
CN107089970B (zh) * 2017-05-26 2020-06-16 迈克斯(如东)化工有限公司 一种制备n-酰基邻氨基苯甲酰胺的方法
CN108191822A (zh) * 2017-12-06 2018-06-22 广东丸美生物技术股份有限公司 一种氯虫苯甲酰胺的合成方法
WO2020026260A1 (en) * 2018-07-31 2020-02-06 Sumitomo Chemical India Ltd. Novel 2-(3-halo-5-methyl-1 h-pyrazol-1-yl)-3-halopyridine compounds and intermediates thereof

Also Published As

Publication number Publication date
CN113874356A (zh) 2021-12-31
MX2021012606A (es) 2021-11-12
AU2025279661A1 (en) 2026-01-15
KR20220002945A (ko) 2022-01-07
WO2020212991A1 (en) 2020-10-22
AU2020257633A1 (en) 2021-12-16
JP7744242B2 (ja) 2025-09-25
US20220177444A1 (en) 2022-06-09
EP3956314A1 (en) 2022-02-23
CO2021013925A2 (es) 2021-10-29
US12459913B2 (en) 2025-11-04
BR112021020840A2 (pt) 2021-12-14
IL287357A (en) 2021-12-01
JP2022529475A (ja) 2022-06-22
CN111825653A (zh) 2020-10-27
KR20250044809A (ko) 2025-04-01
IL287357B1 (en) 2025-11-01
CN113874356B (zh) 2025-04-08

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