AR117446A1 - ANTI-PMEL17 ANTIBODIES AND CONJUGATES THEREOF - Google Patents
ANTI-PMEL17 ANTIBODIES AND CONJUGATES THEREOFInfo
- Publication number
- AR117446A1 AR117446A1 ARP190103765A ARP190103765A AR117446A1 AR 117446 A1 AR117446 A1 AR 117446A1 AR P190103765 A ARP190103765 A AR P190103765A AR P190103765 A ARP190103765 A AR P190103765A AR 117446 A1 AR117446 A1 AR 117446A1
- Authority
- AR
- Argentina
- Prior art keywords
- antibodies
- antigen
- binding fragments
- conjugates
- methods
- Prior art date
Links
- 239000000427 antigen Substances 0.000 abstract 5
- 102000036639 antigens Human genes 0.000 abstract 5
- 108091007433 antigens Proteins 0.000 abstract 5
- 239000012634 fragment Substances 0.000 abstract 5
- 238000000034 method Methods 0.000 abstract 3
- 239000000611 antibody drug conjugate Substances 0.000 abstract 2
- 229940049595 antibody-drug conjugate Drugs 0.000 abstract 2
- 102100025334 Guanine nucleotide-binding protein G(q) subunit alpha Human genes 0.000 abstract 1
- 102100036738 Guanine nucleotide-binding protein subunit alpha-11 Human genes 0.000 abstract 1
- 101000857888 Homo sapiens Guanine nucleotide-binding protein G(q) subunit alpha Proteins 0.000 abstract 1
- 101001072407 Homo sapiens Guanine nucleotide-binding protein subunit alpha-11 Proteins 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940127121 immunoconjugate Drugs 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
Landscapes
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Abstract
La presente solicitud describe anticuerpos anti-PMEL17, fragmentos de unión a antígeno de los mismos, y conjugados de anticuerpo fármaco de dichos anticuerpos o fragmentos de unión a antígeno conjugados a un inhibidor de GNAQ / GNA11. La presente además se refiere a métodos para tratar o prevenir el cáncer usando los anticuerpos, fragmentos de unión a antígeno, y conjugados de anticuerpo fármaco. Además se describen métodos de preparación de anticuerpos, fragmentos de unión a antígeno, y conjugados de anticuerpo fármaco, y métodos de uso de los anticuerpos y fragmentos de unión a antígeno como reactivos de diagnóstico.The present application describes anti-PMEL17 antibodies, antigen-binding fragments thereof, and drug antibody conjugates of such antibodies or antigen-binding fragments conjugated to a GNAQ / GNA11 inhibitor. The present further relates to methods of treating or preventing cancer using the antibodies, antigen-binding fragments, and antibody-drug conjugates. In addition, methods of preparing antibodies, antigen-binding fragments, and antibody-drug conjugates, and methods of using the antibodies and antigen-binding fragments as diagnostic reagents are described.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862783565P | 2018-12-21 | 2018-12-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR117446A1 true AR117446A1 (en) | 2021-08-04 |
Family
ID=77568195
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP190103765A AR117446A1 (en) | 2018-12-21 | 2019-12-19 | ANTI-PMEL17 ANTIBODIES AND CONJUGATES THEREOF |
| ARP210101664A AR122660A2 (en) | 2018-12-21 | 2021-06-17 | ANTI-PMEL17 ANTIBODIES AND CONJUGATES THEREOF |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP210101664A AR122660A2 (en) | 2018-12-21 | 2021-06-17 | ANTI-PMEL17 ANTIBODIES AND CONJUGATES THEREOF |
Country Status (1)
| Country | Link |
|---|---|
| AR (2) | AR117446A1 (en) |
-
2019
- 2019-12-19 AR ARP190103765A patent/AR117446A1/en unknown
-
2021
- 2021-06-17 AR ARP210101664A patent/AR122660A2/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AR122660A2 (en) | 2022-09-28 |
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