AR116506A1 - Proceso e intermediarios para la preparación de fluensulfona - Google Patents
Proceso e intermediarios para la preparación de fluensulfonaInfo
- Publication number
- AR116506A1 AR116506A1 ARP190102726A ARP190102726A AR116506A1 AR 116506 A1 AR116506 A1 AR 116506A1 AR P190102726 A ARP190102726 A AR P190102726A AR P190102726 A ARP190102726 A AR P190102726A AR 116506 A1 AR116506 A1 AR 116506A1
- Authority
- AR
- Argentina
- Prior art keywords
- formula
- fluensulfone
- intermediaries
- preparation
- atoms
- Prior art date
Links
- XSNMWAPKHUGZGQ-UHFFFAOYSA-N fluensulfone Chemical compound FC(F)=C(F)CCS(=O)(=O)C1=NC=C(Cl)S1 XSNMWAPKHUGZGQ-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000006615 aromatic heterocyclic group Chemical group 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 238000005695 dehalogenation reaction Methods 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- -1 heterocyclic fluoroalkenyl sulfones Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- 150000003462 sulfoxides Chemical class 0.000 abstract 1
- 150000003568 thioethers Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/36—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
La presente proporciona un proceso para preparar sulfonas fluoroalquenilo heterocíclicas y sus precursores de tioéter y sulfóxido de la fórmula: Cl-R-S(O)ₙ-(CH₂)₂-CF=CF₂ (fórmula 1) donde R es un anillo heterocíclico aromático de cinco miembros y n es 0, 1 ó 2, que comprende la etapa de deshalogenación de un compuesto de la fórmula: Cl-R-S(O)ₙ-(CH₂)₂-CFX¹-CF₂X² (Intermediario B), donde X¹ y X² son independientemente átomos de halógenos, para remover dichos átomos X¹ y X². También se incluyen compuestos intermediarios.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862736498P | 2018-09-26 | 2018-09-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR116506A1 true AR116506A1 (es) | 2021-05-12 |
Family
ID=68387378
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP190102726A AR116506A1 (es) | 2018-09-26 | 2019-09-25 | Proceso e intermediarios para la preparación de fluensulfona |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US11634397B2 (es) |
| JP (1) | JP7397070B2 (es) |
| KR (1) | KR102608979B1 (es) |
| CN (1) | CN112930342B (es) |
| AR (1) | AR116506A1 (es) |
| AU (1) | AU2019346158B2 (es) |
| WO (1) | WO2020065652A1 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114805240B (zh) * | 2022-06-28 | 2022-09-16 | 湖南速博生物技术有限公司 | 一种一锅法合成氟烯线砜的方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2603647A (en) | 1951-10-18 | 1952-07-15 | Goodrich Co B F | Preparation of 2-mercapto thiazoles |
| US2603648A (en) | 1951-10-18 | 1952-07-15 | Goodrich Co B F | Preparation of 2-mercapto thiazoles |
| HU204022B (en) | 1985-06-20 | 1991-11-28 | Fmc Corp | Nematocidal compositions comprising polyhalogen alkene derivatives and process for producing polyhalogen alkene derivatives |
| IL112721A0 (en) * | 1994-03-10 | 1995-05-26 | Zeneca Ltd | Azole derivatives |
| GB9708280D0 (en) | 1997-04-24 | 1997-06-18 | Zeneca Ltd | Novel process |
| JP3899626B2 (ja) | 1997-12-26 | 2007-03-28 | 宇部興産株式会社 | ２−メルカプトチアゾ−ルの製法 |
| JP2001019685A (ja) | 1999-07-06 | 2001-01-23 | Nippon Bayer Agrochem Co Ltd | 殺センチュウ性トリフルオロブテン類 |
| JP2003113168A (ja) | 2001-09-28 | 2003-04-18 | Bayer Ag | 殺センチュウ性トリフルオロブテン誘導体 |
| DE10221119A1 (de) * | 2002-05-13 | 2003-12-04 | Bayer Cropscience Ag | Verfahren zur Herstellung von substituierten Trifluorethylenen |
| DE10221120A1 (de) | 2002-05-13 | 2003-11-27 | Bayer Cropscience Ag | Verfahren zur Herstellung von substituierten Trifluorethylenen |
| DE10229776A1 (de) | 2002-07-03 | 2004-01-22 | Bayer Cropscience Ag | Verfahren zum Herstellen von heterocyclischen Fluoralkenylsulfonen |
| US20200337311A1 (en) * | 2017-12-20 | 2020-10-29 | Pi Industries Ltd. | Fluoralkenyl compounds, process for preparation and use thereof |
-
2019
- 2019-09-25 AR ARP190102726A patent/AR116506A1/es unknown
- 2019-09-26 KR KR1020217011965A patent/KR102608979B1/ko active Active
- 2019-09-26 WO PCT/IL2019/051063 patent/WO2020065652A1/en not_active Ceased
- 2019-09-26 JP JP2021517567A patent/JP7397070B2/ja active Active
- 2019-09-26 CN CN201980069064.8A patent/CN112930342B/zh active Active
- 2019-09-26 AU AU2019346158A patent/AU2019346158B2/en active Active
- 2019-09-26 US US17/280,146 patent/US11634397B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| BR112021005745A2 (pt) | 2021-07-27 |
| KR20210072010A (ko) | 2021-06-16 |
| AU2019346158B2 (en) | 2025-01-30 |
| US11634397B2 (en) | 2023-04-25 |
| AU2019346158A1 (en) | 2021-05-06 |
| JP2022503882A (ja) | 2022-01-12 |
| US20220002258A1 (en) | 2022-01-06 |
| KR102608979B1 (ko) | 2023-11-30 |
| CN112930342B (zh) | 2024-10-11 |
| WO2020065652A1 (en) | 2020-04-02 |
| JP7397070B2 (ja) | 2023-12-12 |
| CN112930342A (zh) | 2021-06-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112023024906A2 (pt) | Compostos | |
| CL2024000183A1 (es) | Inhibidores de la proteína tirosina fosfatasa | |
| CR20190124A (es) | Inhibidores de ssao de aminopirimidina | |
| PE20241932A1 (es) | Inhibidores de quinasa y usos de los mismos | |
| MX2021012423A (es) | Métodos y composiciones para degradación de proteínas específicas. | |
| BR112022007947A2 (pt) | Uso de modulador de splicing para tratamento que retarda a progressão da doença de huntington | |
| PE20211388A1 (es) | Compuestos | |
| PE20061417A1 (es) | Metodo para sintetizar 3-cianoquinolinas sustituidas y sus intermediarios | |
| AR113688A1 (es) | Proceso para la preparación de compuestos de piridiminio ópticamente activo | |
| MA42341A1 (fr) | Inhibiteur de protéine kinase, son procédé de préparation et son utilisation médicale | |
| BR112022006242A2 (pt) | Compostos aromáticos de arilmetileno como bloqueadores de canal do agitador de potássio kv1,3 | |
| MX2019010642A (es) | Inhibidores de cinasa activada por mitogeno 2 (mk2), sintesis de los mismos, e intermediarios de los mismos. | |
| AR116506A1 (es) | Proceso e intermediarios para la preparación de fluensulfona | |
| CL2018002023A1 (es) | Uso de moduladores de receptores de gabaa para el tratamiento de picor. | |
| CO2021000940A2 (es) | Procedimiento y productos intermedios para la preparación de bilastina | |
| CU24674B1 (es) | Derivados de fenil-n-quinolina y proceso para su preparación | |
| EP4281069A4 (en) | PROCESSES FOR THE PREPARATION OF PYRROLOPYRIDINE-ANILINE COMPOUNDS | |
| MX2023000150A (es) | Compuesto de sulfonamida. | |
| BR112021020234A2 (pt) | Terapia de combinação que compreende compostos da fórmula (i) e agonistas de receptor de glp-1 | |
| CL2020002449A1 (es) | Anticuerpos anti-pfrh5 y fragmentos de unión de antígenos de los mismos. | |
| CO2022011862A2 (es) | Proceso para la preparacion de compuestos de antranilamida artropodicida | |
| BR112021021706A2 (pt) | Processo para preparar inibidores de xpo1 e intermediários para uso na preparação de inibidores de xp01 | |
| MX2021007511A (es) | Procedimiento para la preparacion de anilinas sustituidas. | |
| CO2022001513A2 (es) | Proceso e intermediarios para la preparación de piroxasulfona | |
| BR112021006329A2 (pt) | processo e intermediários para a preparação de certas sulfonamidas nematicidas |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |