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AR116103A1 - Remodelación microbiana guiada, una plataforma para una mejora racional de especies microbianas para la agricultura - Google Patents

Remodelación microbiana guiada, una plataforma para una mejora racional de especies microbianas para la agricultura

Info

Publication number
AR116103A1
AR116103A1 ARP190101870A ARP190101870A AR116103A1 AR 116103 A1 AR116103 A1 AR 116103A1 AR P190101870 A ARP190101870 A AR P190101870A AR P190101870 A ARP190101870 A AR P190101870A AR 116103 A1 AR116103 A1 AR 116103A1
Authority
AR
Argentina
Prior art keywords
microorganisms
microbial
remodeled
gmr
agriculture
Prior art date
Application number
ARP190101870A
Other languages
English (en)
Inventor
Shayin Gottlieb
Rosemary Clark
Austin Davis-Richardson
Douglas Higgins
Alvin Tamsir
Karsten Temme
Sarah Bloch
Original Assignee
Pivot Bio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pivot Bio Inc filed Critical Pivot Bio Inc
Publication of AR116103A1 publication Critical patent/AR116103A1/es

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H1/00—Processes for modifying genotypes ; Plants characterised by associated natural traits
    • A01H1/10—Processes for modifying non-agronomic quality output traits, e.g. for industrial processing; Value added, non-agronomic traits
    • A01H1/101—Processes for modifying non-agronomic quality output traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine or caffeine
    • A01H1/102—Processes for modifying non-agronomic quality output traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine or caffeine involving modified carbohydrate or sugar alcohol metabolism, e.g. starch biosynthesis
    • A01H1/103—Non-starch polysaccharides, e.g. cellulose, fructans or levans
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H1/00—Processes for modifying genotypes ; Plants characterised by associated natural traits
    • A01H1/10—Processes for modifying non-agronomic quality output traits, e.g. for industrial processing; Value added, non-agronomic traits
    • A01H1/101—Processes for modifying non-agronomic quality output traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine or caffeine
    • A01H1/108—Processes for modifying non-agronomic quality output traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine or caffeine involving amino acid content, e.g. synthetic storage proteins or altering amino acid biosynthesis
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    • A01H3/00—Processes for modifying phenotypes, e.g. symbiosis with bacteria
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H5/00—Angiosperms, i.e. flowering plants, characterised by their plant parts; Angiosperms characterised otherwise than by their botanic taxonomy
    • A01H5/06—Roots
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/743—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Agrobacterium; Rhizobium; Bradyrhizobium
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    • C12Y118/06—Oxidoreductases acting on iron-sulfur proteins as donors (1.18) with dinitrogen as acceptor (1.18.6)
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Abstract

Métodos de remodelación microbiana guiada (GMR) para mejorar de manera racional los microorganismos asociados a plantas para que cumplan funciones beneficiosas para las plantas. Los métodos GMR que se describen aquí permiten una optimización genética no intergenérica de las redes reguladoras clave en los microorganismos, que mejoran las funciones beneficiosas para plantas con respecto a los microorganismos de tipo salvaje pero que no presentan los riesgos asociados con los abordajes transgénicos (es decir, una función genética impredecible, problemas con el público y con las normas reguladoras, etc.). La presente divulgación también provee microorganismos remodelados y de composiciones con los mismos. La utilización de microorganismos remodelados y de composiciones con los mismos permitirá que los productores obtengan rendimientos de cultivo más predecibles y productivos sin la degradación de nutrientes, lixiviación o escurrimiento tóxico asociados con los fertilizantes tradicionales sintéticos.
ARP190101870A 2018-06-27 2019-07-02 Remodelación microbiana guiada, una plataforma para una mejora racional de especies microbianas para la agricultura AR116103A1 (es)

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US201862690619P 2018-06-27 2018-06-27

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AR116103A1 true AR116103A1 (es) 2021-03-31

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ARP190101870A AR116103A1 (es) 2018-06-27 2019-07-02 Remodelación microbiana guiada, una plataforma para una mejora racional de especies microbianas para la agricultura

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US (3) US20220127627A1 (es)
EP (1) EP3813511A4 (es)
JP (2) JP2021529522A (es)
KR (1) KR20210057003A (es)
CN (1) CN112584699A (es)
AR (1) AR116103A1 (es)
AU (1) AU2019293248B2 (es)
BR (1) BR112020026676A2 (es)
CA (1) CA3104531A1 (es)
MX (2) MX2020014295A (es)
PH (1) PH12020552234A1 (es)
WO (1) WO2020006246A1 (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10968446B2 (en) 2012-11-01 2021-04-06 Massachusetts Institute Of Technology Directed evolution of synthetic gene cluster
AU2016294506B2 (en) 2015-07-13 2020-02-13 Pivot Bio, Inc. Methods and compositions for improving plant traits
AU2016336328A1 (en) 2015-10-05 2018-04-19 Massachusetts Institute Of Technology Nitrogen fixation using refactored nif clusters
EP3568385A4 (en) 2017-01-12 2021-03-03 Pivot Bio, Inc. PROCEDURES AND COMPOSITIONS FOR IMPROVING PLANT PROPERTIES
BR112020002654A2 (pt) * 2017-08-09 2020-08-18 Pivot Bio, Inc. métodos e composições para melhorar micróbios modificados
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