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AR114134A2 - Sal de maleato de 11-(2-pirrolidin-1-il-etoxi)-14,19-dioxa-5,7,26-triaza-tetraciclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaeno - Google Patents

Sal de maleato de 11-(2-pirrolidin-1-il-etoxi)-14,19-dioxa-5,7,26-triaza-tetraciclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaeno

Info

Publication number
AR114134A2
AR114134A2 ARP190100702A ARP190100702A AR114134A2 AR 114134 A2 AR114134 A2 AR 114134A2 AR P190100702 A ARP190100702 A AR P190100702A AR P190100702 A ARP190100702 A AR P190100702A AR 114134 A2 AR114134 A2 AR 114134A2
Authority
AR
Argentina
Prior art keywords
heptacose
triaza
dioxa
pyrrolidin
tetraciclo
Prior art date
Application number
ARP190100702A
Other languages
English (en)
Original Assignee
Cti Biopharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cti Biopharma Corp filed Critical Cti Biopharma Corp
Publication of AR114134A2 publication Critical patent/AR114134A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Sales maleato de 11-(2-pirrolidin-1-il-etoxi)-14,19-dioxa-5,7,26-triaza-tetraciclo[19.3.1.1(2,6),1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaeno (Compuesto I), de fórmula (1), del cual se descubrió que tiene propiedades mejoradas. También composiciones farmacéuticas que contienen esta sal.
ARP190100702A 2008-12-11 2019-03-20 Sal de maleato de 11-(2-pirrolidin-1-il-etoxi)-14,19-dioxa-5,7,26-triaza-tetraciclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaeno AR114134A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12167608P 2008-12-11 2008-12-11

Publications (1)

Publication Number Publication Date
AR114134A2 true AR114134A2 (es) 2020-07-22

Family

ID=42103945

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP090104835A AR074725A1 (es) 2008-12-11 2009-12-11 Sal de maleato de 11-(2-pirrolidin-1-il-etoxi)-14,19- dioxa-5,7,26-triaza-tetraciclo(19.3.1.1 (2,6).1 (8,12) heptacosa-1(25),2 (26),3,5,8,10,12 (27),16,21,23-decaeno
ARP190100702A AR114134A2 (es) 2008-12-11 2019-03-20 Sal de maleato de 11-(2-pirrolidin-1-il-etoxi)-14,19-dioxa-5,7,26-triaza-tetraciclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaeno

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ARP090104835A AR074725A1 (es) 2008-12-11 2009-12-11 Sal de maleato de 11-(2-pirrolidin-1-il-etoxi)-14,19- dioxa-5,7,26-triaza-tetraciclo(19.3.1.1 (2,6).1 (8,12) heptacosa-1(25),2 (26),3,5,8,10,12 (27),16,21,23-decaeno

Country Status (10)

Country Link
US (1) US8987243B2 (es)
EP (1) EP2376500B1 (es)
AR (2) AR074725A1 (es)
DK (1) DK2376500T3 (es)
ES (1) ES2536276T3 (es)
HR (1) HRP20150413T8 (es)
PL (1) PL2376500T3 (es)
PT (1) PT2376500E (es)
TW (1) TWI457342B (es)
WO (1) WO2010068182A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8133900B2 (en) 2005-11-01 2012-03-13 Targegen, Inc. Use of bi-aryl meta-pyrimidine inhibitors of kinases
BR122021011787B1 (pt) 2005-11-01 2022-01-25 Impact Biomedicines, Inc Inibidores de biaril meta pirimidina de cinases, composição farmacêutica e processo para preparar uma composição farmacêutica
US8604042B2 (en) 2005-11-01 2013-12-10 Targegen, Inc. Bi-aryl meta-pyrimidine inhibitors of kinases
CA2816957A1 (en) 2010-11-07 2012-05-10 Targegen, Inc. Compositions and methods for treating myelofibrosis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101499594B1 (ko) * 2005-11-16 2015-03-09 씨티아이 바이오파마 코포레이션 산소가 결합된 피리미딘 유도체
MY160005A (en) * 2008-12-11 2017-02-15 Cti Biopharma Corp 11-(2-pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo(19.3.1.1(2,6).1(8,12))heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene citrate salt

Also Published As

Publication number Publication date
HRP20150413T8 (xx) 2015-08-14
ES2536276T3 (es) 2015-05-22
US20110263616A1 (en) 2011-10-27
PL2376500T3 (pl) 2015-07-31
TW201028425A (en) 2010-08-01
TWI457342B (zh) 2014-10-21
WO2010068182A1 (en) 2010-06-17
HRP20150413T1 (hr) 2015-07-03
US8987243B2 (en) 2015-03-24
EP2376500B1 (en) 2015-02-25
DK2376500T3 (en) 2015-05-04
EP2376500A1 (en) 2011-10-19
AR074725A1 (es) 2011-02-09
PT2376500E (pt) 2015-06-02

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