AR103484A1 - Triptólido y sus derivados en el tratamiento de tumores y patologías precancerosas de la piel - Google Patents
Triptólido y sus derivados en el tratamiento de tumores y patologías precancerosas de la pielInfo
- Publication number
- AR103484A1 AR103484A1 ARP160100173A ARP160100173A AR103484A1 AR 103484 A1 AR103484 A1 AR 103484A1 AR P160100173 A ARP160100173 A AR P160100173A AR P160100173 A ARP160100173 A AR P160100173A AR 103484 A1 AR103484 A1 AR 103484A1
- Authority
- AR
- Argentina
- Prior art keywords
- derivatives
- treatment
- triptolid
- precancer
- tumors
- Prior art date
Links
- DFBIRQPKNDILPW-CIVMWXNOSA-N Triptolide Chemical compound O=C1OCC([C@@H]2C3)=C1CC[C@]2(C)[C@]12O[C@H]1[C@@H]1O[C@]1(C(C)C)[C@@H](O)[C@]21[C@H]3O1 DFBIRQPKNDILPW-CIVMWXNOSA-N 0.000 title abstract 3
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- YKUJZZHGTWVWHA-UHFFFAOYSA-N triptolide Natural products COC12CC3OC3(C(C)C)C(O)C14OC4CC5C6=C(CCC25C)C(=O)OC6 YKUJZZHGTWVWHA-UHFFFAOYSA-N 0.000 abstract 2
- 230000007170 pathology Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/37—Celastraceae (Staff-tree or Bittersweet family), e.g. tripterygium or spindletree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Alternative & Traditional Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Dispersion Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Compuesto seleccionado de triptólido, sus derivados, y sales farmacéuticamente aceptables de triptólido y sus derivados, o una composición que comprende dicho un compuesto para su uso en el tratamiento tópico y/o prevención de un tumor o patología precancerosa de la piel.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1550512A FR3031900A1 (fr) | 2015-01-22 | 2015-01-22 | Triptolide et ses derives dans le traitement des tumeurs et pathologies pre-cancereuses cutanees |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR103484A1 true AR103484A1 (es) | 2017-05-10 |
Family
ID=53200086
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP160100173A AR103484A1 (es) | 2015-01-22 | 2016-01-22 | Triptólido y sus derivados en el tratamiento de tumores y patologías precancerosas de la piel |
Country Status (4)
| Country | Link |
|---|---|
| AR (1) | AR103484A1 (es) |
| FR (1) | FR3031900A1 (es) |
| TW (1) | TW201632182A (es) |
| WO (1) | WO2016116587A1 (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111440185B (zh) * | 2020-03-31 | 2021-05-14 | 中国农业科学院蜜蜂研究所 | 一种半抗原及其在检测雷公藤乙素和雷公藤甲素方面的应用 |
| CN111494319A (zh) * | 2020-06-15 | 2020-08-07 | 沈阳药科大学 | 雷公藤甲素复方组合物及其制备方法与应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2728466A1 (fr) * | 1994-12-26 | 1996-06-28 | Debiopharm Sa | Utilisation d'un extrait de tripterygium wilfordii hook f et de ses composants pour le traitement du melanome cancereux |
| US6629835B2 (en) * | 2000-08-01 | 2003-10-07 | Metaproteomics, Llc | Combinations of diterpene triepoxide lactones and ditepene lactones or triterpenes for synergistic inhibition of cyclooxygenase-2 |
| US8501214B2 (en) * | 2007-11-26 | 2013-08-06 | Modetex Biomedical Materials & Technology Industrial Corp. | Hydrophilic foam and pharmaceutical dosage form employing the same |
| FR2952072B1 (fr) * | 2009-11-05 | 2013-09-27 | Pf Medicament | Procede de production de triptolide |
-
2015
- 2015-01-22 FR FR1550512A patent/FR3031900A1/fr not_active Withdrawn
-
2016
- 2016-01-22 AR ARP160100173A patent/AR103484A1/es unknown
- 2016-01-22 TW TW105102087A patent/TW201632182A/zh unknown
- 2016-01-22 WO PCT/EP2016/051306 patent/WO2016116587A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2016116587A1 (en) | 2016-07-28 |
| FR3031900A1 (fr) | 2016-07-29 |
| TW201632182A (zh) | 2016-09-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |