AR107834A1 - ANTIBODIES THAT JOIN THE TUMOR NECROSIS FACTOR INDICATED BY GLUCOCORTICOIDS (GITR), METHODS AND USES - Google Patents
ANTIBODIES THAT JOIN THE TUMOR NECROSIS FACTOR INDICATED BY GLUCOCORTICOIDS (GITR), METHODS AND USESInfo
- Publication number
- AR107834A1 AR107834A1 ARP170100580A ARP170100580A AR107834A1 AR 107834 A1 AR107834 A1 AR 107834A1 AR P170100580 A ARP170100580 A AR P170100580A AR P170100580 A ARP170100580 A AR P170100580A AR 107834 A1 AR107834 A1 AR 107834A1
- Authority
- AR
- Argentina
- Prior art keywords
- antibodies
- gitr
- methods
- glucocorticoids
- join
- Prior art date
Links
- 101000801234 Homo sapiens Tumor necrosis factor receptor superfamily member 18 Proteins 0.000 title abstract 3
- 102100033728 Tumor necrosis factor receptor superfamily member 18 Human genes 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 108060008682 Tumor Necrosis Factor Proteins 0.000 title 1
- 239000003862 glucocorticoid Substances 0.000 title 1
- 229940037128 systemic glucocorticoids Drugs 0.000 title 1
- 102000003390 tumor necrosis factor Human genes 0.000 title 1
- 239000000427 antigen Substances 0.000 abstract 3
- 102000036639 antigens Human genes 0.000 abstract 3
- 108091007433 antigens Proteins 0.000 abstract 3
- 239000012634 fragment Substances 0.000 abstract 3
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Landscapes
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
En la presente se proporcionan anticuerpos que se unen de manera específica a GITR. Además, se describen los polinucleótidos relacionados que tienen la capacidad de codificar los anticuerpos específicos para GITR o fragmentos de unión al antígeno proporcionados, las células que expresan los anticuerpos o fragmentos de unión al antígeno proporcionados, así como los vectores asociados y los anticuerpos o fragmentos de unión al antígeno etiquetados de forma detectable. Además, se describen los métodos para usar los anticuerpos proporcionados. Por ejemplo, los anticuerpos proporcionados pueden usarse para aumentar una respuesta inmune en un sujeto contra el cáncer.Antibodies that specifically bind GITR are provided herein. In addition, related polynucleotides that have the ability to encode GITR-specific antibodies or antigen-binding fragments provided, cells expressing the antibodies or antigen-binding fragments provided, as well as associated vectors and antibodies or fragments are described binding to the antigen labeled detectably. In addition, methods for using the antibodies provided are described. For example, the antibodies provided can be used to increase an immune response in a subject against cancer.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201661305270P | 2016-03-08 | 2016-03-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR107834A1 true AR107834A1 (en) | 2018-06-13 |
Family
ID=62683533
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP170100580A AR107834A1 (en) | 2016-03-08 | 2017-03-08 | ANTIBODIES THAT JOIN THE TUMOR NECROSIS FACTOR INDICATED BY GLUCOCORTICOIDS (GITR), METHODS AND USES |
Country Status (1)
| Country | Link |
|---|---|
| AR (1) | AR107834A1 (en) |
-
2017
- 2017-03-08 AR ARP170100580A patent/AR107834A1/en not_active Application Discontinuation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |