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AR105534A1 - Sistema de suministro transdérmico - Google Patents

Sistema de suministro transdérmico

Info

Publication number
AR105534A1
AR105534A1 ARP160102319A ARP160102319A AR105534A1 AR 105534 A1 AR105534 A1 AR 105534A1 AR P160102319 A ARP160102319 A AR P160102319A AR P160102319 A ARP160102319 A AR P160102319A AR 105534 A1 AR105534 A1 AR 105534A1
Authority
AR
Argentina
Prior art keywords
patch
dihydroetorphine
supply system
hydrate
meth
Prior art date
Application number
ARP160102319A
Other languages
English (en)
Inventor
Mundin Gill
Smith Kevin
Johnson Helen
Phyllis Harding Deborah
Whitelock Steve
Original Assignee
Euro Celtique Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa
Publication of AR105534A1 publication Critical patent/AR105534A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061Polyacrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Reivindicación 1: Un parche transdérmico que comprende: una capa que comprende (R)-dihidroetorfina, o una sal o un hidrato, y un poli(met)acrilato; y una capa de base. Reivindicación 29: Un método para elaborar un parche como el reivindicado en cualquiera de las reivindicaciones 1 a 28 que comprende: (i) depositar una composición que comprende (R)-dihidroetorfina, o una sal o un hidrato, y un poli(met)acrilato sobre una capa de base; (ii) evaporar ese solvente para formar una capa que contiene droga; y (iii) en forma opcional, aplicar un protector antiadherente a dicha capa que contiene droga. Reivindicación 31: Un parche transdérmico que comprende (R)-dihidroetorfina para su uso como un parche de 7 días. Reivindicación 34: Un método para el tratamiento del dolor en un sujeto que lo necesita que comprende la aplicación de un parche como el reivindicado en cualquiera de las reivindicaciones 1 a 28 ó 31 en la piel de ese sujeto.
ARP160102319A 2015-07-30 2016-07-29 Sistema de suministro transdérmico AR105534A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1513442.2A GB201513442D0 (en) 2015-07-30 2015-07-30 Transdermal patch

Publications (1)

Publication Number Publication Date
AR105534A1 true AR105534A1 (es) 2017-10-11

Family

ID=54062903

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP160102319A AR105534A1 (es) 2015-07-30 2016-07-29 Sistema de suministro transdérmico

Country Status (16)

Country Link
US (1) US20180221298A1 (es)
EP (1) EP3328432A1 (es)
JP (1) JP6793718B2 (es)
KR (1) KR20180031039A (es)
CN (1) CN108136028A (es)
AR (1) AR105534A1 (es)
AU (1) AU2016298762A1 (es)
BR (1) BR112018001564A2 (es)
CA (1) CA2994109A1 (es)
GB (1) GB201513442D0 (es)
IL (1) IL256994A (es)
MA (1) MA42522A (es)
MX (1) MX2018001320A (es)
SG (1) SG10201913253TA (es)
TW (1) TW201707693A (es)
WO (1) WO2017017453A1 (es)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10231248A (ja) * 1997-02-19 1998-09-02 T T S Gijutsu Kenkyusho:Kk ジヒドロエトルフィン含有経皮吸収型製剤
US6716449B2 (en) * 2000-02-08 2004-04-06 Euro-Celtique S.A. Controlled-release compositions containing opioid agonist and antagonist
CN1780611B (zh) * 2003-04-30 2013-01-30 珀杜医药公司 包括活性剂部分以及在活性剂层远侧的逆转剂的抗改造透皮剂型
PE20081297A1 (es) * 2003-04-30 2008-09-17 Purdue Pharma Lp Forma de dosificacion transdermica resistente a la manipulacion
DE102005011517A1 (de) * 2005-03-10 2006-09-21 Grünenthal GmbH Transdermales therapeutisches System zur Verabreichung von Analgetika
TWI541246B (zh) * 2008-12-08 2016-07-11 歐陸斯迪公司 二氫羥戊甲嗎啡
GB201309654D0 (en) * 2013-05-30 2013-07-17 Euro Celtique Sa Method

Also Published As

Publication number Publication date
US20180221298A1 (en) 2018-08-09
CA2994109A1 (en) 2017-02-02
MX2018001320A (es) 2018-08-15
KR20180031039A (ko) 2018-03-27
AU2016298762A1 (en) 2018-02-15
GB201513442D0 (en) 2015-09-16
IL256994A (en) 2018-03-29
BR112018001564A2 (pt) 2018-09-18
WO2017017453A1 (en) 2017-02-02
JP6793718B2 (ja) 2020-12-02
EP3328432A1 (en) 2018-06-06
SG10201913253TA (en) 2020-03-30
MA42522A (fr) 2018-06-06
TW201707693A (zh) 2017-03-01
CN108136028A (zh) 2018-06-08
JP2018528176A (ja) 2018-09-27

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Legal Events

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