AR105492A1 - METHODS FOR THE DIAGNOSIS AND TREATMENT OF INTESTINAL INFLAMMATORY DISEASE - Google Patents
METHODS FOR THE DIAGNOSIS AND TREATMENT OF INTESTINAL INFLAMMATORY DISEASEInfo
- Publication number
- AR105492A1 AR105492A1 ARP160102273A ARP160102273A AR105492A1 AR 105492 A1 AR105492 A1 AR 105492A1 AR P160102273 A ARP160102273 A AR P160102273A AR P160102273 A ARP160102273 A AR P160102273A AR 105492 A1 AR105492 A1 AR 105492A1
- Authority
- AR
- Argentina
- Prior art keywords
- methods
- treatment
- diagnosis
- inflammatory disease
- biomarkers
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 238000003745 diagnosis Methods 0.000 title 1
- 208000027866 inflammatory disease Diseases 0.000 title 1
- 230000000968 intestinal effect Effects 0.000 title 1
- 206010009900 Colitis ulcerative Diseases 0.000 abstract 2
- 208000011231 Crohn disease Diseases 0.000 abstract 2
- 208000022559 Inflammatory bowel disease Diseases 0.000 abstract 2
- 201000006704 Ulcerative Colitis Diseases 0.000 abstract 2
- 239000000090 biomarker Substances 0.000 abstract 2
- 102000006495 integrins Human genes 0.000 abstract 2
- 108010044426 integrins Proteins 0.000 abstract 2
- 208000017189 Gastrointestinal inflammatory disease Diseases 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 239000000092 prognostic biomarker Substances 0.000 abstract 1
- 230000004043 responsiveness Effects 0.000 abstract 1
Landscapes
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Se proporcionan biomarcadores predictivos de la capacidad de respuesta a los antagonistas de la integrina b7, incluyendo anticuerpos de la subunidad de la integrina anti-b7, y métodos de uso de tales biomarcadores. Además, se proporcionan métodos de tratamiento de trastornos inflamatorios gastrointestinales, tales como enfermedades inflamatorias intestinales incluyendo la colitis ulcerosa y la enfermedad de Crohn. También se proporcionan métodos de uso de tales biomarcadores predictivos para el tratamiento de enfermedades inflamatorias intestinales incluyendo la colitis ulcerosa y la enfermedad de Crohn.Biomarkers predictive of responsiveness to b7 integrin antagonists, including antibodies to the anti-b7 integrin subunit, and methods of use of such biomarkers are provided. In addition, methods of treating gastrointestinal inflammatory disorders, such as inflammatory bowel diseases including ulcerative colitis and Crohn's disease, are provided. Methods of using such predictive biomarkers for the treatment of inflammatory bowel diseases including ulcerative colitis and Crohn's disease are also provided.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562197293P | 2015-07-27 | 2015-07-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR105492A1 true AR105492A1 (en) | 2017-10-11 |
Family
ID=60244676
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP160102273A AR105492A1 (en) | 2015-07-27 | 2016-07-26 | METHODS FOR THE DIAGNOSIS AND TREATMENT OF INTESTINAL INFLAMMATORY DISEASE |
Country Status (1)
| Country | Link |
|---|---|
| AR (1) | AR105492A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113226357A (en) * | 2018-11-23 | 2021-08-06 | 斯特赖克药物公司 | Bispecific conjugates |
-
2016
- 2016-07-26 AR ARP160102273A patent/AR105492A1/en unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113226357A (en) * | 2018-11-23 | 2021-08-06 | 斯特赖克药物公司 | Bispecific conjugates |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |