AR105177A2 - Forma cristalina de ácido 8-ciano-1-ciclopropil-7-(1s,6s-2,8-diazabiciclo-(4.3.0)nonan-8-il)-6-flúor-1,4-dihidro-4-oxo-3-quinolincarboxílico - Google Patents
Forma cristalina de ácido 8-ciano-1-ciclopropil-7-(1s,6s-2,8-diazabiciclo-(4.3.0)nonan-8-il)-6-flúor-1,4-dihidro-4-oxo-3-quinolincarboxílicoInfo
- Publication number
- AR105177A2 AR105177A2 ARP160101954A ARP160101954A AR105177A2 AR 105177 A2 AR105177 A2 AR 105177A2 AR P160101954 A ARP160101954 A AR P160101954A AR P160101954 A ARP160101954 A AR P160101954A AR 105177 A2 AR105177 A2 AR 105177A2
- Authority
- AR
- Argentina
- Prior art keywords
- chinolincarboxyl
- cyclopropil
- diazabiciclo
- ciano
- nonan
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- -1 Pradofloxacin trihydrate Chemical class 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229960001248 pradofloxacin Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
Trihidrato de pradofloxacina, como a composiciones antibacterianas que lo contienen.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102004015981A DE102004015981A1 (de) | 2004-04-01 | 2004-04-01 | Neue kirstalline Form von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR105177A2 true AR105177A2 (es) | 2017-09-13 |
Family
ID=34962324
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP050101004A AR048099A1 (es) | 2004-04-01 | 2005-03-15 | FORMA CRISTALINA DE ÁCIDO 8-CIANO-1CICLOPROPIL-7-(1S,6S-2,8-DIAZABICICLO)(4.3.0)NONAN--IL)-6FLUOR-1,4-DIHIDRO-4-OXO-3-QUINOLINCARBOXíLICO |
| ARP160101954A AR105177A2 (es) | 2004-04-01 | 2016-06-28 | Forma cristalina de ácido 8-ciano-1-ciclopropil-7-(1s,6s-2,8-diazabiciclo-(4.3.0)nonan-8-il)-6-flúor-1,4-dihidro-4-oxo-3-quinolincarboxílico |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP050101004A AR048099A1 (es) | 2004-04-01 | 2005-03-15 | FORMA CRISTALINA DE ÁCIDO 8-CIANO-1CICLOPROPIL-7-(1S,6S-2,8-DIAZABICICLO)(4.3.0)NONAN--IL)-6FLUOR-1,4-DIHIDRO-4-OXO-3-QUINOLINCARBOXíLICO |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US7977484B2 (es) |
| EP (1) | EP1737859B1 (es) |
| JP (1) | JP5190259B2 (es) |
| KR (1) | KR101217678B1 (es) |
| CN (1) | CN100591681C (es) |
| AR (2) | AR048099A1 (es) |
| AT (1) | ATE450536T1 (es) |
| AU (1) | AU2005231918B2 (es) |
| BR (1) | BRPI0509529B8 (es) |
| CA (1) | CA2561635C (es) |
| CY (2) | CY1109762T1 (es) |
| DE (3) | DE102004015981A1 (es) |
| DK (1) | DK1737859T3 (es) |
| ES (1) | ES2335899T3 (es) |
| GT (1) | GT200500043A (es) |
| HR (1) | HRP20100097T1 (es) |
| IL (1) | IL178353A (es) |
| MY (1) | MY140998A (es) |
| NO (1) | NO337279B1 (es) |
| NZ (1) | NZ550226A (es) |
| PE (1) | PE20060170A1 (es) |
| PL (1) | PL1737859T3 (es) |
| PT (1) | PT1737859E (es) |
| RU (1) | RU2383543C2 (es) |
| SI (1) | SI1737859T1 (es) |
| SV (1) | SV2006002070A (es) |
| TW (1) | TWI350755B (es) |
| UA (1) | UA84329C2 (es) |
| UY (1) | UY28828A1 (es) |
| WO (1) | WO2005097789A1 (es) |
| ZA (1) | ZA200608072B (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102006010642A1 (de) * | 2006-03-08 | 2007-09-27 | Bayer Healthcare Aktiengesellschaft | Arzneimittelformulierungen, enthaltend Fluorchinolone |
| DE102006010643A1 (de) | 2006-03-08 | 2007-09-13 | Bayer Healthcare Aktiengesellschaft | Arzneimittel enthaltend Fluorchinolone |
| DE102007026550A1 (de) * | 2007-06-08 | 2008-12-11 | Bayer Healthcare Ag | Extrudate mit verbesserter Geschmacksmaskierung |
| ES2886088T3 (es) | 2017-02-13 | 2021-12-16 | Bayer Animal Health Gmbh | Composición líquida que contiene pradofloxacina |
| CN115710267A (zh) * | 2022-11-30 | 2023-02-24 | 天津大学 | 一种普拉沙星水合物晶体及其制备方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19546249A1 (de) * | 1995-12-12 | 1997-06-19 | Bayer Ag | Neue Kristallmodifikation des 1-Cyclopropyl-7-([S,S]-2,8-diazabicyclo[4,3,0]non-8-yl)-6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäure Hydrochlorid (CDCH), Verfahren zu dessen Herstellung und diese enthaltende pharmazeutische Zubereitungen |
| WO1997031001A1 (de) | 1996-02-23 | 1997-08-28 | Bayer Aktiengesellschaft | Gegebenenfalls substituierte 8-cyan-1-cyclopropyl-7-(2,8-diazabicyclo-[4.3.0]-nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäuren und ihre derivate |
| DE19854356A1 (de) | 1998-11-25 | 2000-05-31 | Bayer Ag | Kristallmodifikation A von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo-/4.3.0/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure |
| DE19854357A1 (de) | 1998-11-25 | 2000-05-31 | Bayer Ag | Semi-Hydrochlorid von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo/4.3.0/ -nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure |
| DE19854355A1 (de) * | 1998-11-25 | 2000-05-31 | Bayer Ag | Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure |
| DE19908449A1 (de) | 1999-02-26 | 2000-08-31 | Bayer Ag | Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure |
| DE19908448A1 (de) * | 1999-02-26 | 2000-08-31 | Bayer Ag | Kristallmodifikation D von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo[4.3.0)nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino incarbonsäure |
| US6627646B2 (en) * | 2001-07-17 | 2003-09-30 | Sepracor Inc. | Norastemizole polymorphs |
-
2004
- 2004-04-01 DE DE102004015981A patent/DE102004015981A1/de not_active Withdrawn
-
2005
- 2005-03-10 GT GT200500043A patent/GT200500043A/es unknown
- 2005-03-15 AR ARP050101004A patent/AR048099A1/es not_active Application Discontinuation
- 2005-03-19 CA CA2561635A patent/CA2561635C/en not_active Expired - Lifetime
- 2005-03-19 WO PCT/EP2005/002953 patent/WO2005097789A1/de not_active Ceased
- 2005-03-19 PL PL05716236T patent/PL1737859T3/pl unknown
- 2005-03-19 EP EP05716236A patent/EP1737859B1/de not_active Expired - Lifetime
- 2005-03-19 CN CN200580010668A patent/CN100591681C/zh not_active Expired - Lifetime
- 2005-03-19 DK DK05716236.4T patent/DK1737859T3/da active
- 2005-03-19 NZ NZ550226A patent/NZ550226A/en not_active IP Right Cessation
- 2005-03-19 UA UAA200611491A patent/UA84329C2/ru unknown
- 2005-03-19 SI SI200530913T patent/SI1737859T1/sl unknown
- 2005-03-19 JP JP2007505435A patent/JP5190259B2/ja not_active Expired - Lifetime
- 2005-03-19 RU RU2006138362/04A patent/RU2383543C2/ru active
- 2005-03-19 US US11/547,420 patent/US7977484B2/en active Active
- 2005-03-19 AT AT05716236T patent/ATE450536T1/de active
- 2005-03-19 AU AU2005231918A patent/AU2005231918B2/en not_active Expired
- 2005-03-19 HR HR20100097T patent/HRP20100097T1/hr unknown
- 2005-03-19 DE DE502005008620T patent/DE502005008620D1/de not_active Expired - Lifetime
- 2005-03-19 BR BRPI0509529A patent/BRPI0509529B8/pt active IP Right Grant
- 2005-03-19 ES ES05716236T patent/ES2335899T3/es not_active Expired - Lifetime
- 2005-03-19 PT PT05716236T patent/PT1737859E/pt unknown
- 2005-03-30 UY UY28828A patent/UY28828A1/es not_active Application Discontinuation
- 2005-03-30 MY MYPI20051428A patent/MY140998A/en unknown
- 2005-03-31 PE PE2005000369A patent/PE20060170A1/es not_active Application Discontinuation
- 2005-03-31 TW TW094110161A patent/TWI350755B/zh not_active IP Right Cessation
- 2005-04-01 SV SV2005002070A patent/SV2006002070A/es unknown
-
2006
- 2006-09-28 IL IL178353A patent/IL178353A/en active IP Right Grant
- 2006-09-28 ZA ZA2006/08072A patent/ZA200608072B/en unknown
- 2006-10-26 KR KR1020067022260A patent/KR101217678B1/ko not_active Expired - Lifetime
- 2006-10-31 NO NO20064988A patent/NO337279B1/no unknown
-
2010
- 2010-01-29 CY CY20101100090T patent/CY1109762T1/el unknown
-
2011
- 2011-10-11 DE DE201112100055 patent/DE122011100055I1/de active Pending
- 2011-10-11 CY CY2011018C patent/CY2011018I1/el unknown
-
2016
- 2016-06-28 AR ARP160101954A patent/AR105177A2/es not_active Application Discontinuation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |