AR093827A1 - Agentes antibacterianos de tetrahidroquinolina triciclica - Google Patents
Agentes antibacterianos de tetrahidroquinolina triciclicaInfo
- Publication number
- AR093827A1 AR093827A1 ARP130103443A ARP130103443A AR093827A1 AR 093827 A1 AR093827 A1 AR 093827A1 AR P130103443 A ARP130103443 A AR P130103443A AR P130103443 A ARP130103443 A AR P130103443A AR 093827 A1 AR093827 A1 AR 093827A1
- Authority
- AR
- Argentina
- Prior art keywords
- triciclic
- tetrahydroquinoline
- antibacterial agents
- halo
- formula
- Prior art date
Links
- LBUJPTNKIBCYBY-UHFFFAOYSA-N 1,2,3,4-tetrahydroquinoline Chemical compound C1=CC=C2CCCNC2=C1 LBUJPTNKIBCYBY-UHFFFAOYSA-N 0.000 title 2
- 239000003242 anti bacterial agent Substances 0.000 title 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 3
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/20—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
- A01N47/38—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the group >N—CO—N< where at least one nitrogen atom is part of a heterocyclic ring; Thio analogues thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5386—1,4-Oxazines, e.g. morpholine spiro-condensed or forming part of bridged ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Wood Science & Technology (AREA)
- Dentistry (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Reivindicación 1: Un compuesto caracterizado porque tiene la fórmula (1), en la que: R¹ es seleccionado del grupo que consiste en los compuestos de fórmula (2), (3), (4) y (5) que están opcionalmente sustituidos con R²; R² es alquilo C₁₋₆ o fenilo opcionalmente sustituido con halo; X e Y son independientemente H, halo o alquilo C₁₋₆; o una sal, solvato o un hidrato del mismo; a condición de que cuando R¹ es resto de fórmula (3) y R² es fenilo, al menos uno de X e Y es halo.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261705709P | 2012-09-26 | 2012-09-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR093827A1 true AR093827A1 (es) | 2015-06-24 |
Family
ID=49301686
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP130103443A AR093827A1 (es) | 2012-09-26 | 2013-09-25 | Agentes antibacterianos de tetrahidroquinolina triciclica |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US8952149B2 (es) |
| EP (1) | EP2900064A1 (es) |
| JP (1) | JP2015531375A (es) |
| KR (1) | KR20150045513A (es) |
| CN (1) | CN104684396A (es) |
| AR (1) | AR093827A1 (es) |
| AU (1) | AU2013323687A1 (es) |
| BR (1) | BR112015006220A2 (es) |
| CA (1) | CA2884850A1 (es) |
| MX (1) | MX2015003770A (es) |
| PH (1) | PH12015500518A1 (es) |
| UY (1) | UY35050A (es) |
| WO (1) | WO2014052387A1 (es) |
| ZA (1) | ZA201501640B (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8889671B2 (en) | 2013-01-23 | 2014-11-18 | Astrazeneca Ab | Compounds and methods for treating bacterial infections |
| CA2948438A1 (en) | 2014-05-29 | 2015-12-03 | Entasis Therapeutics Limited | Fused, spirocyclic heteroaromatic compounds for the treatment of bacterial infections |
| JP7316903B2 (ja) | 2018-12-27 | 2023-07-28 | エルジー エナジー ソリューション リミテッド | 二次電池用正極活物質及びその製造方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7208490B2 (en) | 2002-10-07 | 2007-04-24 | Pharmacia & Upjohn Company Llc | Tricyclic tetrahydroquinoline antibacterial agents |
| CA2606847A1 (en) | 2005-05-09 | 2006-11-16 | Warner-Lambert Company Llc | Antibacterial agents |
| DOP2006000268A (es) | 2005-12-22 | 2007-07-31 | Pfizer Prod Inc | Agentes antibacterianos |
| RU2010103101A (ru) | 2007-07-02 | 2011-08-10 | Астразенека Аб (Se) | Химические соединения |
-
2013
- 2013-09-24 US US14/034,832 patent/US8952149B2/en not_active Expired - Fee Related
- 2013-09-25 AR ARP130103443A patent/AR093827A1/es unknown
- 2013-09-25 WO PCT/US2013/061580 patent/WO2014052387A1/en not_active Ceased
- 2013-09-25 BR BR112015006220A patent/BR112015006220A2/pt not_active IP Right Cessation
- 2013-09-25 KR KR1020157007514A patent/KR20150045513A/ko not_active Ceased
- 2013-09-25 AU AU2013323687A patent/AU2013323687A1/en not_active Abandoned
- 2013-09-25 EP EP13771743.5A patent/EP2900064A1/en not_active Withdrawn
- 2013-09-25 MX MX2015003770A patent/MX2015003770A/es unknown
- 2013-09-25 JP JP2015534615A patent/JP2015531375A/ja active Pending
- 2013-09-25 CA CA2884850A patent/CA2884850A1/en not_active Abandoned
- 2013-09-25 CN CN201380050445.4A patent/CN104684396A/zh active Pending
- 2013-09-26 UY UY35050A patent/UY35050A/es not_active Application Discontinuation
-
2014
- 2014-12-23 US US14/580,870 patent/US20150111884A1/en not_active Abandoned
-
2015
- 2015-03-10 ZA ZA2015/01640A patent/ZA201501640B/en unknown
- 2015-03-10 PH PH12015500518A patent/PH12015500518A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014052387A1 (en) | 2014-04-03 |
| JP2015531375A (ja) | 2015-11-02 |
| KR20150045513A (ko) | 2015-04-28 |
| CA2884850A1 (en) | 2014-04-03 |
| ZA201501640B (en) | 2016-01-27 |
| US20150111884A1 (en) | 2015-04-23 |
| PH12015500518A1 (en) | 2015-04-27 |
| CN104684396A (zh) | 2015-06-03 |
| US8952149B2 (en) | 2015-02-10 |
| US20140088093A1 (en) | 2014-03-27 |
| BR112015006220A2 (pt) | 2017-07-04 |
| AU2013323687A1 (en) | 2015-03-19 |
| EP2900064A1 (en) | 2015-08-05 |
| MX2015003770A (es) | 2015-07-14 |
| UY35050A (es) | 2014-04-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |