AR093530A1 - Adyuvante de vacunacion, preparacion, y vacunas que lo contienen - Google Patents
Adyuvante de vacunacion, preparacion, y vacunas que lo contienenInfo
- Publication number
- AR093530A1 AR093530A1 ARP130104247A ARP130104247A AR093530A1 AR 093530 A1 AR093530 A1 AR 093530A1 AR P130104247 A ARP130104247 A AR P130104247A AR P130104247 A ARP130104247 A AR P130104247A AR 093530 A1 AR093530 A1 AR 093530A1
- Authority
- AR
- Argentina
- Prior art keywords
- preparation
- antigens
- vaccination
- assistant
- vaccines containing
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 3
- 238000002255 vaccination Methods 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
- 239000000427 antigen Substances 0.000 abstract 4
- 102000036639 antigens Human genes 0.000 abstract 4
- 108091007433 antigens Proteins 0.000 abstract 4
- 239000000203 mixture Substances 0.000 abstract 3
- HSINOMROUCMIEA-FGVHQWLLSA-N (2s,4r)-4-[(3r,5s,6r,7r,8s,9s,10s,13r,14s,17r)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid Chemical compound C([C@@]12C)C[C@@H](O)C[C@H]1[C@@H](CC)[C@@H](O)[C@@H]1[C@@H]2CC[C@]2(C)[C@@H]([C@H](C)C[C@H](C)C(O)=O)CC[C@H]21 HSINOMROUCMIEA-FGVHQWLLSA-N 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 108010008038 Synthetic Vaccines Proteins 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 239000003613 bile acid Substances 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000009144 enzymatic modification Effects 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000003071 parasitic effect Effects 0.000 abstract 1
- 244000052769 pathogen Species 0.000 abstract 1
- 239000001397 quillaja saponaria molina bark Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229930182490 saponin Natural products 0.000 abstract 1
- 150000007949 saponins Chemical class 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/08—Clostridium, e.g. Clostridium tetani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Composición, preparación y empleo como adyuvante para uso animal o humano, de una formulación que comprende por lo menos un ácido biliar o sus sales y saponina, para potenciar la respuesta inmune contra un antígeno, que puede estar bien definido o no, incluyendo pero sin limitarse a bacterinas, antígenos y preparados antigénicos virales, bacterianos, parasitarios, y antígenos asociados con enfermedades tales como distintos tipos de cáncer. Los antígenos empleados pueden ser aislados de patógenos, así como productos de su modificación química o enzimática, antígenos recombinantes o sintéticos, o mezclas de los anteriores.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| UY0001034506A UY34506A (es) | 2012-12-10 | 2012-12-10 | Adyuvante de vacunación, preparación y vacunas que lo contienen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR093530A1 true AR093530A1 (es) | 2015-06-10 |
Family
ID=50934708
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP130104247A AR093530A1 (es) | 2012-12-10 | 2013-11-18 | Adyuvante de vacunacion, preparacion, y vacunas que lo contienen |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20150313991A1 (es) |
| EP (1) | EP2929894B1 (es) |
| AR (1) | AR093530A1 (es) |
| AU (1) | AU2013360504B2 (es) |
| BR (1) | BR112015013625A2 (es) |
| CL (1) | CL2015001618A1 (es) |
| UY (1) | UY34506A (es) |
| WO (1) | WO2014092528A1 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108272824A (zh) * | 2018-03-11 | 2018-07-13 | 张显英 | 一种胆汁提取工艺 |
| EP3856197A4 (en) * | 2018-09-25 | 2021-12-15 | Yichang Humanwell Pharmaceutical Co., Ltd. | CONTROLLER OF TGR5 SIGNALING AS IMMUNMODULATORY MEANS |
| EP3669890A1 (en) * | 2018-12-18 | 2020-06-24 | Croda International PLC | Filamentous nanoparticles having vaccine adjuvant effect |
| RU2741834C1 (ru) * | 2020-07-17 | 2021-01-29 | Муса Тажудинович Абидов | Вакцина и способ повышения иммуногенности и специфической активности средств профилактики инфекций |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
| CA1331443C (en) * | 1987-05-29 | 1994-08-16 | Charlotte A. Kensil | Saponin adjuvant |
| JPH06503231A (ja) * | 1991-09-18 | 1994-04-14 | アムジエン・インコーポレーテツド | 胆汁酸塩を含有するｂ型肝炎ワクチン製剤 |
| AU1077795A (en) * | 1993-09-30 | 1995-04-18 | Seed Capital Investments (Sci) B.V. | Compounds with adjuvant activity |
| UA56132C2 (uk) | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
| AUPO517897A0 (en) * | 1997-02-19 | 1997-04-11 | Csl Limited | Chelating immunostimulating complexes |
| GB9817052D0 (en) | 1998-08-05 | 1998-09-30 | Smithkline Beecham Biolog | Vaccine |
| TR200200776T2 (tr) * | 1999-09-24 | 2002-06-21 | Smithkline Beecham Biologicals S.A. | Burun içi grip virüsü aşısı. |
| ATE503493T1 (de) * | 2001-02-23 | 2011-04-15 | Glaxosmithkline Biolog Sa | Influenza vakzinzusammensetzungen zur intradermaler verabreichung |
| DK1742659T3 (da) | 2004-04-05 | 2013-06-03 | Zoetis P Llc | Mikrofluidiserede olie-i-vand-emulsioner og vaccinesammensætninger |
| US8343498B2 (en) * | 2008-10-12 | 2013-01-01 | Massachusetts Institute Of Technology | Adjuvant incorporation in immunonanotherapeutics |
-
2012
- 2012-12-10 UY UY0001034506A patent/UY34506A/es not_active Application Discontinuation
-
2013
- 2013-11-18 AR ARP130104247A patent/AR093530A1/es unknown
- 2013-12-09 WO PCT/MX2013/000161 patent/WO2014092528A1/es not_active Ceased
- 2013-12-09 BR BR112015013625A patent/BR112015013625A2/pt not_active IP Right Cessation
- 2013-12-09 US US14/651,093 patent/US20150313991A1/en not_active Abandoned
- 2013-12-09 AU AU2013360504A patent/AU2013360504B2/en not_active Ceased
- 2013-12-09 EP EP13863256.7A patent/EP2929894B1/en not_active Not-in-force
-
2015
- 2015-06-10 CL CL2015001618A patent/CL2015001618A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014092528A1 (es) | 2014-06-19 |
| EP2929894A1 (en) | 2015-10-14 |
| EP2929894B1 (en) | 2018-02-21 |
| AU2013360504A1 (en) | 2015-07-02 |
| UY34506A (es) | 2014-06-30 |
| US20150313991A1 (en) | 2015-11-05 |
| AU2013360504B2 (en) | 2016-12-01 |
| EP2929894A4 (en) | 2015-12-02 |
| BR112015013625A2 (pt) | 2017-07-11 |
| CL2015001618A1 (es) | 2016-05-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |