AR099405A1 - Composición antifúngica tópica para el tratamiento de onicomicosis - Google Patents
Composición antifúngica tópica para el tratamiento de onicomicosisInfo
- Publication number
- AR099405A1 AR099405A1 ARP150100418A ARP150100418A AR099405A1 AR 099405 A1 AR099405 A1 AR 099405A1 AR P150100418 A ARP150100418 A AR P150100418A AR P150100418 A ARP150100418 A AR P150100418A AR 099405 A1 AR099405 A1 AR 099405A1
- Authority
- AR
- Argentina
- Prior art keywords
- composition
- weight
- amount
- treatment
- onicomycosis
- Prior art date
Links
- 229940054190 hydroxypropyl chitosan Drugs 0.000 abstract 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000002966 varnish Substances 0.000 abstract 2
- 208000010195 Onychomycosis Diseases 0.000 abstract 1
- 229940121375 antifungal agent Drugs 0.000 abstract 1
- 239000003429 antifungal agent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- SCKYRAXSEDYPSA-UHFFFAOYSA-N ciclopirox Chemical compound ON1C(=O)C=C(C)C=C1C1CCCCC1 SCKYRAXSEDYPSA-UHFFFAOYSA-N 0.000 abstract 1
- 239000003623 enhancer Substances 0.000 abstract 1
- 230000035515 penetration Effects 0.000 abstract 1
- 239000004014 plasticizer Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 201000005882 tinea unguium Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/736—Chitin; Chitosan; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q3/00—Manicure or pedicure preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q3/00—Manicure or pedicure preparations
- A61Q3/02—Nail coatings
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Birds (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Emergency Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
Abstract
Un barniz de uñas que consiste esencialmente en ciclopirox como un agente antimicótico, hidroxipropil quitosano como un agente formador de película, agua y un alcanol inferior como solvente. También se refiere a dicho barniz de uñas para uso en el tratamiento de onicomicosis. Reivindicación 1: Una composición que consiste esencialmente en: a) ciclopirox y/o al menos una sal farmacéuticamente aceptable del mismo en una cantidad de al menos aproximadamente 7% en peso, b) hidroxipropil quitosano, c) agua, d) al menos un alcanol C₁₋₄; cuya composición no contiene plastificantes y/o intensificadores de la penetración. Reivindicación 7: Una composición de acuerdo con la reivindicación 1, que consiste esencialmente en: a) ciclopirox y/o al menos una sal farmacéuticamente aceptable del mismo en una cantidad de desde 7 a 9% en peso de la composición, b) hidroxipropil quitosano en una cantidad de desde 0.1 a 4% en peso de la composición, c) agua en una cantidad de desde 10.0 a 30% en peso de la composición, d) al menos un alcanol C₁₋₄ en una cantidad de desde 65 a 85% en peso de la composición.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14156113.4A EP2910245A1 (en) | 2014-02-21 | 2014-02-21 | Topical antifungal composition for treating onychomycosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR099405A1 true AR099405A1 (es) | 2016-07-20 |
Family
ID=50150638
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP150100418A AR099405A1 (es) | 2014-02-21 | 2015-02-12 | Composición antifúngica tópica para el tratamiento de onicomicosis |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20170056386A1 (es) |
| EP (2) | EP2910245A1 (es) |
| JP (1) | JP2017506647A (es) |
| KR (1) | KR20160121538A (es) |
| CN (1) | CN106102717A (es) |
| AR (1) | AR099405A1 (es) |
| AU (1) | AU2015220883A1 (es) |
| CA (1) | CA2938922A1 (es) |
| CL (1) | CL2016002083A1 (es) |
| DO (1) | DOP2016000213A (es) |
| EA (1) | EA201691687A1 (es) |
| IL (1) | IL246800A0 (es) |
| MD (1) | MD20160097A2 (es) |
| MX (1) | MX2016010787A (es) |
| PE (1) | PE20161345A1 (es) |
| PH (1) | PH12016501661A1 (es) |
| UY (1) | UY36007A (es) |
| WO (1) | WO2015124586A1 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106580927A (zh) * | 2017-02-17 | 2017-04-26 | 中国药科大学 | 一种环吡酮胺喷膜剂及其制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3544983A1 (de) | 1985-12-19 | 1987-06-25 | Hoechst Ag | Antimykotisch wirksamer nagellack |
| DE69907341T2 (de) | 1998-02-09 | 2004-01-22 | Macrochem Corp., Lexington | Antimykotischer nagellack |
| JP5170486B2 (ja) | 1998-09-10 | 2013-03-27 | バイオイコール ア−ゲー | 局所適用性産物 |
| DE10035991A1 (de) | 2000-07-24 | 2002-02-14 | Polichem Sa | Nagellackzusammensetzung |
| EP1958638A1 (en) * | 2007-02-14 | 2008-08-20 | Polichem S.A. | Use of chitosans to increase nail growth rate |
-
2014
- 2014-02-21 EP EP14156113.4A patent/EP2910245A1/en not_active Withdrawn
-
2015
- 2015-02-12 AR ARP150100418A patent/AR099405A1/es unknown
- 2015-02-18 AU AU2015220883A patent/AU2015220883A1/en not_active Abandoned
- 2015-02-18 JP JP2016553543A patent/JP2017506647A/ja active Pending
- 2015-02-18 EP EP15706205.0A patent/EP3107528A1/en not_active Withdrawn
- 2015-02-18 WO PCT/EP2015/053352 patent/WO2015124586A1/en not_active Ceased
- 2015-02-18 EA EA201691687A patent/EA201691687A1/ru unknown
- 2015-02-18 KR KR1020167023005A patent/KR20160121538A/ko not_active Withdrawn
- 2015-02-18 MX MX2016010787A patent/MX2016010787A/es unknown
- 2015-02-18 PE PE2016001254A patent/PE20161345A1/es not_active Application Discontinuation
- 2015-02-18 MD MDA20160097A patent/MD20160097A2/ro not_active Application Discontinuation
- 2015-02-18 US US15/119,818 patent/US20170056386A1/en not_active Abandoned
- 2015-02-18 CN CN201580008780.7A patent/CN106102717A/zh active Pending
- 2015-02-18 CA CA2938922A patent/CA2938922A1/en not_active Abandoned
- 2015-02-20 UY UY0001036007A patent/UY36007A/es not_active Application Discontinuation
-
2016
- 2016-07-17 IL IL246800A patent/IL246800A0/en unknown
- 2016-08-18 CL CL2016002083A patent/CL2016002083A1/es unknown
- 2016-08-18 DO DO2016000213A patent/DOP2016000213A/es unknown
- 2016-08-19 PH PH12016501661A patent/PH12016501661A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL246800A0 (en) | 2016-08-31 |
| CA2938922A1 (en) | 2015-08-27 |
| MD20160097A2 (ro) | 2016-12-31 |
| UY36007A (es) | 2015-04-30 |
| EA201691687A1 (ru) | 2016-12-30 |
| DOP2016000213A (es) | 2016-11-30 |
| AU2015220883A1 (en) | 2016-08-25 |
| PE20161345A1 (es) | 2016-12-17 |
| CN106102717A (zh) | 2016-11-09 |
| EP2910245A1 (en) | 2015-08-26 |
| EP3107528A1 (en) | 2016-12-28 |
| WO2015124586A1 (en) | 2015-08-27 |
| JP2017506647A (ja) | 2017-03-09 |
| KR20160121538A (ko) | 2016-10-19 |
| PH12016501661A1 (en) | 2016-10-03 |
| CL2016002083A1 (es) | 2017-06-09 |
| US20170056386A1 (en) | 2017-03-02 |
| MX2016010787A (es) | 2017-04-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |