[go: up one dir, main page]

AR096845A1 - Sales de (e)-n-((1s,4s)-4-(dimetilamino)-1,4-difenilciclohexil)-n-metilcinamamida - Google Patents

Sales de (e)-n-((1s,4s)-4-(dimetilamino)-1,4-difenilciclohexil)-n-metilcinamamida

Info

Publication number
AR096845A1
AR096845A1 ARP140102525A ARP140102525A AR096845A1 AR 096845 A1 AR096845 A1 AR 096845A1 AR P140102525 A ARP140102525 A AR P140102525A AR P140102525 A ARP140102525 A AR P140102525A AR 096845 A1 AR096845 A1 AR 096845A1
Authority
AR
Argentina
Prior art keywords
acid
methyllinamamide
diphenylciclohexil
dimethylamine
salts
Prior art date
Application number
ARP140102525A
Other languages
English (en)
Inventor
Dr Gru Michael
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of AR096845A1 publication Critical patent/AR096845A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
    • C07C233/41—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C55/00—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
    • C07C55/02—Dicarboxylic acids
    • C07C55/06—Oxalic acid
    • C07C55/07—Salts thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C55/00—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
    • C07C55/02—Dicarboxylic acids
    • C07C55/10—Succinic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/13—Dicarboxylic acids
    • C07C57/145—Maleic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/13—Dicarboxylic acids
    • C07C57/15—Fumaric acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
    • C07C59/255—Tartaric acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Detergent Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Una sal de (E)-N-((1s,4s)-4-(dimetilamino)-1,4-difenilciclohexil)-N-metilcinamamida. Reivindicación 1: Una sal caracterizada porque es de (E)-N-((1s,4s)-4-(dimetilamino)-1,4-difenilciclohexil)-N-metilcinamamida y un ácido policarboxílico. Reivindicación 7: La sal de acuerdo con cualquiera de las reivindicaciones precedentes, caracterizada porque el ácido policarboxílico se selecciona entre el grupo que consiste en: ácido oxálico, ácido glutárico, ácido succínico, ácido fumárico, ácido maleico, ácido málico, y ácido tartárico.
ARP140102525A 2013-07-17 2014-07-08 Sales de (e)-n-((1s,4s)-4-(dimetilamino)-1,4-difenilciclohexil)-n-metilcinamamida AR096845A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP13176916 2013-07-17

Publications (1)

Publication Number Publication Date
AR096845A1 true AR096845A1 (es) 2016-02-03

Family

ID=48793097

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP140102525A AR096845A1 (es) 2013-07-17 2014-07-08 Sales de (e)-n-((1s,4s)-4-(dimetilamino)-1,4-difenilciclohexil)-n-metilcinamamida

Country Status (2)

Country Link
AR (1) AR096845A1 (es)
WO (1) WO2015007388A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017114596A1 (en) * 2015-12-28 2017-07-06 Grünenthal GmbH Crystalline forms of (cis)-n-(4-(dimethylamino)-1,4-diphenylcyclohexyl)-n-methyl-cinnamamide
WO2017114597A1 (en) * 2015-12-28 2017-07-06 Grünenthal GmbH Pharmaceutical dosage forms comprising ((cis)-n-(4-(dimethylamino)-1,4- diphenylcyclohexyl)-n-methylcinnamamide

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2009228642B2 (en) 2008-03-27 2013-11-07 Grunenthal Gmbh Substituted 4-aminocyclohexane derivatives

Also Published As

Publication number Publication date
WO2015007388A1 (en) 2015-01-22

Similar Documents

Publication Publication Date Title
ECSP16067303A (es) Heteroarilos y usos de estos
GT201700245A (es) Sal de (s)-csa de s-ketamina, sal de (r)-csa de s-ketamina y procesos para la preparación de s-ketamina
AR094918A1 (es) Compuestos de tetrahidropirrolotiazina como inhibidores de bace
CU20200080A7 (es) Kit que comprende un inhibidor de lats para el suministro ocular
MX2017002670A (es) Inhibidores de glucosidasa.
MX2017008136A (es) Sal de l-tartrato de pridopidina.
CO2017003279A2 (es) Compuestos y composiciones farmacéuticamente aceptables de los mismos, eficaces como inhibidores de mk2
CL2017002452A1 (es) Nuevos compuestos bicíclicos
AR101995A1 (es) COMPUESTOS ANTAGONISTAS DE INTEGRINA avb6
EA201591137A1 (ru) Ингибиторы mk2 и их применения
CL2017002179A1 (es) Sales de inhibidor de pi3k y procesos de preparación
LT3323814T (lt) (2s)-n-[(1s)-1-ciano-2-feniletil]-1,4-oksazepan-2-karboksamidai kaip dipeptidil peptidazės 1 inhibitoriai
UY34201A (es) Compuestos de azaindol y métodos para el tratamiento de vih.
CR20150589A (es) Compuestos de biheteroarilo y usos de los mismos
AR094970A1 (es) Un inhibidor de mdm2 derivado de ácido benzoico para el tratamiento del cáncer
EA201690764A1 (ru) Ингибитор грелин-o-ацилтрансферазы
AR103680A1 (es) Inhibidores selectivos de bace1
EA201591406A1 (ru) C-19 модифицированные тритерпеноиды с ингибиторной активностью созревания вич
MX381123B (es) Sales de acrilato metalicas para incrementar la resistencia de fusion del polimero.
EP3704716A4 (en) VENTILATED METAL STORAGE PACKAGING (VMSO)
EA201891783A1 (ru) Композиция для растворения аморфных дитиазинов и способ ее применения
EA201591678A1 (ru) Антиперспирантные композиции
PL3475420T3 (pl) Kompozycja paszowa zawierająca kwaśną proteazę
EA201791174A1 (ru) Антимикотическое соединение
ES2650914T3 (es) Sales de adición de ácidos de 5alfa-hidroxi-6beta-[2-(1H-imidazol-4-il)etilamino]colestan-3beta-ol

Legal Events

Date Code Title Description
FB Suspension of granting procedure