AR096390A1 - COMPOSITIONS OF ARNi DE SERPINA1 AND ITS METHODS OF USE - Google Patents
COMPOSITIONS OF ARNi DE SERPINA1 AND ITS METHODS OF USEInfo
- Publication number
- AR096390A1 AR096390A1 ARP140102031A ARP140102031A AR096390A1 AR 096390 A1 AR096390 A1 AR 096390A1 AR P140102031 A ARP140102031 A AR P140102031A AR P140102031 A ARP140102031 A AR P140102031A AR 096390 A1 AR096390 A1 AR 096390A1
- Authority
- AR
- Argentina
- Prior art keywords
- serpina1
- methods
- rnai agents
- arni
- compositions
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 102100022712 Alpha-1-antitrypsin Human genes 0.000 title 1
- 241000320892 Clerodendrum phlomidis Species 0.000 title 1
- 101000823116 Homo sapiens Alpha-1-antitrypsin Proteins 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 108091030071 RNAI Proteins 0.000 abstract 3
- 101150069374 Serpina1 gene Proteins 0.000 abstract 3
- 230000009368 gene silencing by RNA Effects 0.000 abstract 3
- 101150035628 Serpine1 gene Proteins 0.000 abstract 1
- 238000009825 accumulation Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000019423 liver disease Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Se relaciona con agentes de ARNi, por ejemplo, agentes de ARNi de doble hebra, que se dirigen contra el gen de Serpina1, y métodos para usar dichos agentes de ARNi para inhibir la expresión de Serpina1 y métodos para tratar a sujetos que tienen una enfermedad asociada a Serpina1, tal como un trastorno de hígado. Composición farmacéutica; vector; célula; método para reducir la acumulación de Serpina1.It relates to RNAi agents, for example, double-stranded RNAi agents, which are directed against the Serpina1 gene, and methods for using said RNAi agents to inhibit Serpina1 expression and methods for treating subjects who have a disease. associated with Serpina1, such as a liver disorder. Pharmaceutical composition; vector; cell; method to reduce the accumulation of Serpine1.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361826125P | 2013-05-22 | 2013-05-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR096390A1 true AR096390A1 (en) | 2015-12-30 |
Family
ID=56120468
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP140102031A AR096390A1 (en) | 2013-05-22 | 2014-05-22 | COMPOSITIONS OF ARNi DE SERPINA1 AND ITS METHODS OF USE |
Country Status (1)
| Country | Link |
|---|---|
| AR (1) | AR096390A1 (en) |
-
2014
- 2014-05-22 AR ARP140102031A patent/AR096390A1/en unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |