AR088056A1 - MODULACION DE TIMOSINA b-4 EN LA PIEL, METODO PARA MEJORAR EL ASPECTO ESTETICO DE LA PIEL, PARA TRATAR ARRUGAS, COMPOSICION COSMETICA - Google Patents
MODULACION DE TIMOSINA b-4 EN LA PIEL, METODO PARA MEJORAR EL ASPECTO ESTETICO DE LA PIEL, PARA TRATAR ARRUGAS, COMPOSICION COSMETICAInfo
- Publication number
- AR088056A1 AR088056A1 ARP120103565A AR088056A1 AR 088056 A1 AR088056 A1 AR 088056A1 AR P120103565 A ARP120103565 A AR P120103565A AR 088056 A1 AR088056 A1 AR 088056A1
- Authority
- AR
- Argentina
- Prior art keywords
- skin
- thymosin
- active agent
- improve
- cosmetic composition
- Prior art date
Links
- 239000002537 cosmetic Substances 0.000 title abstract 3
- 230000037303 wrinkles Effects 0.000 title 1
- 239000013543 active substance Substances 0.000 abstract 6
- 102000007501 Thymosin Human genes 0.000 abstract 4
- 108010046075 Thymosin Proteins 0.000 abstract 4
- LCJVIYPJPCBWKS-NXPQJCNCSA-N thymosin Chemical compound SC[C@@H](N)C(=O)N[C@H](CO)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CO)C(=O)N[C@H](CO)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@H]([C@H](C)O)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](C(C)C)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@H](CCC(O)=O)C(O)=O LCJVIYPJPCBWKS-NXPQJCNCSA-N 0.000 abstract 4
- 150000004492 retinoid derivatives Chemical class 0.000 abstract 3
- 241001438327 Berchemia lineata Species 0.000 abstract 1
- 240000008365 Celosia argentea Species 0.000 abstract 1
- 235000000722 Celosia argentea Nutrition 0.000 abstract 1
- 241000196324 Embryophyta Species 0.000 abstract 1
- 241001102691 Ixora Species 0.000 abstract 1
- 241000738807 Maesa japonica Species 0.000 abstract 1
- 244000064622 Physalis edulis Species 0.000 abstract 1
- 230000032683 aging Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A61K8/445—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof aromatic, i.e. the carboxylic acid directly linked to the aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/06—Preparations for care of the skin for countering cellulitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Mycology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Alternative & Traditional Medicine (AREA)
- Medical Informatics (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Métodos para prevenir, mejorar, o reducir signos dermatológicos del envejecimiento que utilizan agentes activos, aparte de un retinoide, que estimulan la expresión de timosina b-4 en la piel. Métodos para seleccionar sustancias que estimulan los niveles de expresión de timosina b-4 y los métodos para usar agentes activos identificados por el protocolo de selección en el tratamiento de la piel. Reivindicación 1: Un método para mejorar el aspecto estético de la piel humana que comprende aplicar de forma tópica a un área de la piel que lo necesita una cantidad eficaz de un agente activo, aparte de un retinoide, que estimula la expresión de timosina b-4 humana, durante un tiempo suficiente para mejorar el aspecto estético de dicha piel humana. Reivindicación 10: Una composición cosmética para mejorar el aspecto estético de la piel humana que comprende un vehículo cosméticamente aceptable, y una cantidad eficaz de un agente activo, aparte de un retinoide, que aumenta timosina b-4, donde dicha cantidad eficaz del agente activo comprende desde aproximadamente 0,00001% hasta aproximadamente 90% en peso de la composición total. Reivindicación 11: La composición cosmética de acuerdo con la reivindicación 10, donde dicho agente activo es un extracto botánico que proviene de una planta seleccionada del grupo compuesto por Maesa japonica, Celosia argentea, Berchemia lineata, Ixora chinesis, Physalis mínima, y sus combinaciones. Reivindicación 17: La composición de acuerdo con la reivindicación 16 donde dicho agente es un compuesto de la formula (1).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/324,150 US8632827B2 (en) | 2011-12-13 | 2011-12-13 | Modulation of thymosin beta-4 in skin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR088056A1 true AR088056A1 (es) | 2014-05-07 |
Family
ID=48572200
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP120103565 AR088056A1 (es) | 2011-12-13 | 2012-09-26 | MODULACION DE TIMOSINA b-4 EN LA PIEL, METODO PARA MEJORAR EL ASPECTO ESTETICO DE LA PIEL, PARA TRATAR ARRUGAS, COMPOSICION COSMETICA |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US8632827B2 (es) |
| EP (2) | EP2790720A4 (es) |
| AR (1) | AR088056A1 (es) |
| ES (1) | ES2639920T3 (es) |
| PL (1) | PL2790666T3 (es) |
| TW (1) | TW201323005A (es) |
| WO (1) | WO2013089832A1 (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011087654A1 (en) | 2009-12-22 | 2011-07-21 | Avon Products, Inc. | Paxillin stimulating compositions and cosmetic uses thereof |
| US20110159125A1 (en) | 2009-12-29 | 2011-06-30 | Avon Products, Inc. | CGRP Compositions and Uses Thereof |
| CN106727054A (zh) | 2010-06-30 | 2017-05-31 | 雅芳产品公司 | 用于刺激magp‑1以改善皮肤外观的组合物和方法 |
| US10195136B2 (en) | 2011-08-24 | 2019-02-05 | Avon Products, Inc. | Collagen and elastin stimulating compositions and uses thereof |
| US10092574B2 (en) | 2012-09-26 | 2018-10-09 | Valorisation-Recherche, Limited Partnership | Inhibitors of polynucleotide repeat-associated RNA foci and uses thereof |
| TW201422246A (zh) * | 2012-12-11 | 2014-06-16 | Avon Prod Inc | 藉由調節ｗｉｐｉ－１改善皮膚老化外觀之方法 |
| US10758476B1 (en) | 2017-09-18 | 2020-09-01 | Type A Brands, Llc | Deodorant with sweat-activated technology |
| US20220226464A1 (en) | 2019-05-28 | 2022-07-21 | Massachusetts Institute Of Technology | Methods and compositions for modulating immune responses |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05320037A (ja) * | 1992-05-20 | 1993-12-03 | Tsuneo Nanba | 抗酸化剤 |
| US5869540A (en) | 1996-03-29 | 1999-02-09 | Smith; Walter P. | Herbal treatments for improving skin appearance |
| ATE292473T1 (de) * | 1998-07-30 | 2005-04-15 | Us Gov Health & Human Serv | Thymosin beta 4 stimuliert wundheilung |
| US20040067227A1 (en) | 2001-11-02 | 2004-04-08 | Goldstein Allan L. | Inhibition or reversal of skin aging by actin-sequestering peptides |
| EP1145709A1 (de) * | 2000-04-14 | 2001-10-17 | Laboratoires Serobiologiques | Verwendung von Naturstoffen zur Herstellung von kosmetischen Zubereitungen |
| WO2002047706A2 (en) | 2000-12-15 | 2002-06-20 | Pharmacia Corporation | Selective cox-2 inhibition from plant extracts |
| US7101663B2 (en) | 2001-03-02 | 2006-09-05 | University of Pittsburgh—of the Commonwealth System of Higher Education | PCR method |
| AU2002309842B2 (en) * | 2001-05-17 | 2006-02-02 | Regenerx Biopharmaceuticals, Inc. | Treating epidermlyosis bullosa with thymosin beta 4 |
| US20050154046A1 (en) | 2004-01-12 | 2005-07-14 | Longgui Wang | Methods of treating an inflammatory-related disease |
| US6821524B2 (en) * | 2002-06-03 | 2004-11-23 | Jan Marini Skin Research, Inc. | Cosmetic skin care compositions |
| US7488753B2 (en) * | 2003-10-09 | 2009-02-10 | Pacific Arrow Limited | Composition comprising triterpene saponins and compounds with angeloyl functional group, methods for preparing same and uses thereof |
| KR20070052694A (ko) | 2004-01-09 | 2007-05-22 | 더 리젠트스 오브 더 유니이버시티 오브 캘리포니아 | 유전자 발현을 위한 세포-유형-특이적 패턴 |
| JP5279163B2 (ja) * | 2004-02-06 | 2013-09-04 | 丸善製薬株式会社 | 抗老化剤、血小板凝集抑制剤、抗酸化剤、抗アレルギー剤及び飲食品 |
| US20050196450A1 (en) | 2004-03-04 | 2005-09-08 | Elka Touitou | Method and composition for burned skin |
| CA2571642A1 (en) | 2004-07-09 | 2006-02-16 | University Of Pittsburgh - Of The Commonwealth System Of Higher Educatio N | Identification of markers in lung and breast cancer |
| US7514092B2 (en) * | 2004-12-22 | 2009-04-07 | Avon Products, Inc. | Compositions and methods of their use for improving the condition and appearance of skin |
| US20070224150A1 (en) * | 2005-03-24 | 2007-09-27 | Yongji Chung | Growth factor for hair and skin treatment |
| JP4716497B2 (ja) * | 2005-08-09 | 2011-07-06 | 株式会社 資生堂 | 皮膚外用剤およびヒアルロニダーゼ阻害剤 |
| KR101480700B1 (ko) | 2007-11-30 | 2015-01-12 | (주)아모레퍼시픽 | 복방 생약 추출물을 유효성분으로 함유하는 피부 외용제조성물 |
| WO2010022073A1 (en) | 2008-08-19 | 2010-02-25 | Dbc, Llc | Compositions and methods for utilizing the same |
| EP2177630A1 (en) | 2008-10-02 | 2010-04-21 | Institut Gustave Roussy | Methods for predicting or monitoring whether a patient affected by a cancer is responsive to a treatment with a molecule of the taxoid family |
| JP2010090069A (ja) * | 2008-10-09 | 2010-04-22 | Shiseido Co Ltd | 美白剤および皮膚外用剤 |
| US20110236325A1 (en) | 2010-01-21 | 2011-09-29 | NellOne Therapeutics, Inc. | Methods to treat or prevent a skin condition using a nell1 peptide |
| US8318222B2 (en) | 2010-02-19 | 2012-11-27 | Mary Kay, Inc. | Topical skin care formulation |
| TWI397425B (zh) * | 2010-05-25 | 2013-06-01 | 中國醫藥大學 | 用於抗氧化、抑制基質金屬蛋白酶活性及／或生成、及／或促進膠原蛋白生成之白仙丹葉萃取物及其用途 |
| US8455518B2 (en) | 2010-12-28 | 2013-06-04 | Avon Products, Inc. | Method of treating skin with microRNA modulators |
| MX349544B (es) | 2011-12-13 | 2017-08-02 | Avon Prod Inc | Extractos de maesa japonica y métodos de uso. |
-
2011
- 2011-12-13 US US13/324,150 patent/US8632827B2/en not_active Expired - Fee Related
-
2012
- 2012-08-07 EP EP12857934.9A patent/EP2790720A4/en not_active Withdrawn
- 2012-08-07 WO PCT/US2012/049833 patent/WO2013089832A1/en not_active Ceased
- 2012-08-20 TW TW101130160A patent/TW201323005A/zh unknown
- 2012-09-26 AR ARP120103565 patent/AR088056A1/es unknown
- 2012-12-11 ES ES12857747.5T patent/ES2639920T3/es active Active
- 2012-12-11 EP EP12857747.5A patent/EP2790666B1/en active Active
- 2012-12-11 PL PL12857747T patent/PL2790666T3/pl unknown
-
2013
- 2013-12-09 US US14/100,514 patent/US9114089B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| ES2639920T3 (es) | 2017-10-30 |
| EP2790720A4 (en) | 2015-10-14 |
| EP2790720A1 (en) | 2014-10-22 |
| US8632827B2 (en) | 2014-01-21 |
| EP2790666B1 (en) | 2017-06-28 |
| EP2790666A4 (en) | 2016-08-03 |
| US20130149397A1 (en) | 2013-06-13 |
| US20140154343A1 (en) | 2014-06-05 |
| US9114089B2 (en) | 2015-08-25 |
| EP2790666A2 (en) | 2014-10-22 |
| PL2790666T3 (pl) | 2017-12-29 |
| TW201323005A (zh) | 2013-06-16 |
| WO2013089832A1 (en) | 2013-06-20 |
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