AR086184A1 - Procedimiento de preparacion de un producto de plasma deplecionado de uno o varios factores trombogenicos - Google Patents
Procedimiento de preparacion de un producto de plasma deplecionado de uno o varios factores trombogenicosInfo
- Publication number
- AR086184A1 AR086184A1 ARP120101346A ARP120101346A AR086184A1 AR 086184 A1 AR086184 A1 AR 086184A1 AR P120101346 A ARP120101346 A AR P120101346A AR P120101346 A ARP120101346 A AR P120101346A AR 086184 A1 AR086184 A1 AR 086184A1
- Authority
- AR
- Argentina
- Prior art keywords
- procedure
- preparation
- thrombogenic factors
- plasma product
- product
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 230000002885 thrombogenetic effect Effects 0.000 title abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 abstract 2
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000005635 Caprylic acid (CAS 124-07-2) Substances 0.000 abstract 1
- 238000011210 chromatographic step Methods 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 238000005194 fractionation Methods 0.000 abstract 1
- 239000003456 ion exchange resin Substances 0.000 abstract 1
- 229920003303 ion-exchange polymer Polymers 0.000 abstract 1
- 229960002446 octanoic acid Drugs 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229940127557 pharmaceutical product Drugs 0.000 abstract 1
- 238000001556 precipitation Methods 0.000 abstract 1
- 238000001179 sorption measurement Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/16—Blood plasma; Blood serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0281—Apparatus for treatment of blood or blood constituents prior to transfusion, e.g. washing, filtering or thawing
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Developmental Biology & Embryology (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Reivindicación 1: Procedimiento de preparación de un producto de plasma deplecionado de uno o varios factores trombogénicos, que incluye la combinación de al menos dos etapas elegidas entre: una etapa de fraccionamiento con etanol; una etapa de filtración-adsorción; una etapa de precipitación con ácido caprílico; y una etapa de cromatografía con resina intercambiadora de iones.Reivindicación 12: Producto de plasma deplecionado de uno o varios factores trombogénicos, susceptible de obtenerse mediante el procedimiento de cualquiera de las reivindicaciones 1 a 11. Reivindicación 16: Producto farmacéutico que incluye el producto de plasma según cualquiera de las reivindicaciones 12 a 15 y al menos un vehículo farmacéuticamente aceptable.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1153438A FR2974301B1 (fr) | 2011-04-20 | 2011-04-20 | Procede de preparation d'un produit plasmatique deplete en un ou plusieurs facteurs thrombogenes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR086184A1 true AR086184A1 (es) | 2013-11-27 |
Family
ID=45974358
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP120101346A AR086184A1 (es) | 2011-04-20 | 2012-04-19 | Procedimiento de preparacion de un producto de plasma deplecionado de uno o varios factores trombogenicos |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP2699248B1 (es) |
| AR (1) | AR086184A1 (es) |
| ES (1) | ES2624245T3 (es) |
| FR (1) | FR2974301B1 (es) |
| TW (2) | TWI584810B (es) |
| WO (1) | WO2012143484A1 (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2974301B1 (fr) * | 2011-04-20 | 2013-08-23 | Lab Francais Du Fractionnement | Procede de preparation d'un produit plasmatique deplete en un ou plusieurs facteurs thrombogenes |
| CN103613662A (zh) * | 2013-11-26 | 2014-03-05 | 中国医学科学院输血研究所 | 一种从人血浆中分离纯化人抗凝血酶-ⅲ的方法 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE545232A (es) | 1955-02-23 | |||
| NL289602A (es) | 1962-03-01 | |||
| US4272521A (en) * | 1979-07-16 | 1981-06-09 | Cutter Laboratories, Inc. | Purified immune serum globulin |
| US4764369A (en) | 1983-07-14 | 1988-08-16 | New York Blood Center Inc. | Undenatured virus-free biologically active protein derivatives |
| DE3734923C1 (de) * | 1987-10-15 | 1989-01-26 | Biotest Pharma Gmbh | Verfahren zur Herstellung einer sterilen Plasmaproteinloesung,die Fibrinogen und den Gerinnungsfaktor XIII enthaelt |
| DE59009020D1 (de) * | 1990-03-22 | 1995-06-08 | Biotest Pharma Gmbh | Verfahren zur Herstellung eines intravenös verträglichen Immunglobulin-G-Präparates. |
| FR2676231A1 (fr) | 1991-05-07 | 1992-11-13 | Aetsrn | Concentre de facteur xi de la coagulation sanguine a haute activite specifique, approprie a usage therapeutique et son procede de preparation. |
| FR2706466B1 (fr) | 1993-06-14 | 1995-08-25 | Aetsrn | Concentré d'immunoglobulines G à usage thérapeutique et procédé de production dudit concentré. |
| US5886154A (en) | 1997-06-20 | 1999-03-23 | Lebing; Wytold R. | Chromatographic method for high yield purification and viral inactivation of antibodies |
| US6281336B1 (en) | 1998-06-09 | 2001-08-28 | Statens Serum Institut | Process for producing immunoglobulins for intravenous administration and other immunoglobulin products |
| RU2197500C2 (ru) | 1998-06-09 | 2003-01-27 | Статенс Серум Институт | Способ получения иммуноглобулинов для внутривенного введения и другие иммуноглобулиновые продукты |
| FR2824568B1 (fr) * | 2001-05-11 | 2004-04-09 | Lab Francais Du Fractionnement | Procede de preparation de concentres d'immunoglobulines humaines a usage therapeutique |
| FR2853551B1 (fr) | 2003-04-09 | 2006-08-04 | Lab Francais Du Fractionnement | Formulation stabilisante pour compositions d'immunoglobulines g sous forme liquide et sous forme lyophilisee |
| FR2895263B1 (fr) * | 2005-12-26 | 2008-05-30 | Lab Francais Du Fractionnement | Concentre d'immunoglobines g (lg) appauvri en anticorps anti-a et anti-b, et en igg polyreactives |
| EP2435474A2 (en) | 2009-05-27 | 2012-04-04 | Baxter International Inc | A method to produce a highly concentrated immunoglobulin preparation for subcutaneous use |
| GB201006753D0 (en) | 2010-04-22 | 2010-06-09 | Biotest Ag | Process for preparing an immunolobulin composition |
| FR2974301B1 (fr) * | 2011-04-20 | 2013-08-23 | Lab Francais Du Fractionnement | Procede de preparation d'un produit plasmatique deplete en un ou plusieurs facteurs thrombogenes |
| US20140044742A1 (en) | 2011-04-20 | 2014-02-13 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies | Method for preparing a depleted plasma material consisting of one or more thrombogenic factors |
-
2011
- 2011-04-20 FR FR1153438A patent/FR2974301B1/fr active Active
-
2012
- 2012-04-19 ES ES12714726.2T patent/ES2624245T3/es active Active
- 2012-04-19 EP EP12714726.2A patent/EP2699248B1/fr not_active Revoked
- 2012-04-19 TW TW103140594A patent/TWI584810B/zh not_active IP Right Cessation
- 2012-04-19 AR ARP120101346A patent/AR086184A1/es unknown
- 2012-04-19 WO PCT/EP2012/057228 patent/WO2012143484A1/fr not_active Ceased
- 2012-04-19 TW TW101113897A patent/TWI526214B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP2699248A1 (fr) | 2014-02-26 |
| EP2699248B1 (fr) | 2017-02-08 |
| FR2974301B1 (fr) | 2013-08-23 |
| TWI526214B (zh) | 2016-03-21 |
| TW201306850A (zh) | 2013-02-16 |
| TW201507727A (zh) | 2015-03-01 |
| FR2974301A1 (fr) | 2012-10-26 |
| ES2624245T3 (es) | 2017-07-13 |
| WO2012143484A1 (fr) | 2012-10-26 |
| TWI584810B (zh) | 2017-06-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |