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AR072442A1 - Metodo para la terapia del cancer, uso, kit - Google Patents

Metodo para la terapia del cancer, uso, kit

Info

Publication number
AR072442A1
AR072442A1 ARP090100051A ARP090100051A AR072442A1 AR 072442 A1 AR072442 A1 AR 072442A1 AR P090100051 A ARP090100051 A AR P090100051A AR P090100051 A ARP090100051 A AR P090100051A AR 072442 A1 AR072442 A1 AR 072442A1
Authority
AR
Argentina
Prior art keywords
kit
cancer therapy
treatment
cancer
medicament
Prior art date
Application number
ARP090100051A
Other languages
English (en)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40365425&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR072442(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of AR072442A1 publication Critical patent/AR072442A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Reivindicacion 1: El uso del compuesto de formula (1) o una sal farmacéuticamente aceptable del mismo, para la fabricacion de un medicamento destinado al tratamiento del cáncer, en particular de tumores solidos. Reivindicacion 16: Un método para la fabricacion de un medicamento destinado al tratamiento del cáncer, en particular de tumores solidos, caracterizado porque se emplea el compuesto de la formula (1) en una cantidad terapéuticamente eficaz. Reivindicacion 34: Los métodos y usos segun la reivindicacion 33 para el tratamiento de cáncer pancreático.
ARP090100051A 2008-01-11 2009-01-08 Metodo para la terapia del cancer, uso, kit AR072442A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2044708P 2008-01-11 2008-01-11

Publications (1)

Publication Number Publication Date
AR072442A1 true AR072442A1 (es) 2010-09-01

Family

ID=40365425

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP090100051A AR072442A1 (es) 2008-01-11 2009-01-08 Metodo para la terapia del cancer, uso, kit

Country Status (17)

Country Link
US (1) US20090181944A1 (es)
EP (1) EP2244713A1 (es)
JP (3) JP5612482B2 (es)
KR (2) KR20140007979A (es)
CN (1) CN101909633B (es)
AR (1) AR072442A1 (es)
AU (1) AU2009203776A1 (es)
BR (1) BRPI0906831A2 (es)
CA (1) CA2710913A1 (es)
CL (1) CL2009000040A1 (es)
CR (1) CR11510A (es)
IL (1) IL206361A0 (es)
MA (1) MA33076B1 (es)
RU (1) RU2010133489A (es)
TW (1) TW200936139A (es)
WO (1) WO2009087130A1 (es)
ZA (1) ZA201004859B (es)

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WO2012050370A2 (ko) * 2010-10-15 2012-04-19 성균관대학교산학협력단 감마-세크레타제 저해제를 유효성분으로 함유하는 류마티스성 관절염의 예방 또는 치료용 조성물
US20120114638A1 (en) * 2010-11-08 2012-05-10 John Boylan Combination therapy
US20120225860A1 (en) * 2011-03-02 2012-09-06 John Frederick Boylan Method for administration of a gamma secretase inhibitor
TWI530489B (zh) 2011-03-22 2016-04-21 必治妥美雅史谷比公司 雙(氟烷基)-1,4-苯二氮呯酮化合物
JO3148B1 (ar) 2011-07-27 2017-09-20 Lilly Co Eli مركب مثبط لإشارات مسار notch
CA2884309A1 (en) 2012-09-07 2014-03-13 Massachusetts Eye And Ear Infirmary Methods and compositions for regenerating hair cells and/or supporting cells from differentiated cochlear cells or differentiated utricular cells by modulation of notch and cmyc activity
HK1211875A1 (en) 2012-09-07 2016-06-03 Massachusetts Eye & Ear Infirmary Treating hearing loss
US9249157B2 (en) 2012-09-21 2016-02-02 Bristol-Myers Squibb Company Tricyclic heterocycle compounds
CN104854094A (zh) 2012-09-21 2015-08-19 百时美施贵宝公司 氟烷基二苯并二氮杂*酮化合物
US9242940B2 (en) 2012-09-21 2016-01-26 Bristol-Myers Squibb Company N-substituted bis(fluoroalkyl)-1,4-benzodiazepinone compounds
US9273075B2 (en) 2012-09-21 2016-03-01 Bristol-Myers Squibb Company Prodrugs of 1,4-benzodiazepinone compounds
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CN104797569A (zh) 2012-09-21 2015-07-22 百时美施贵宝公司 取代的1,5-苯并二氮杂*酮化合物
CN104822677A (zh) 2012-09-21 2015-08-05 百时美施贵宝公司 氟烷基-1,4-苯并二氮杂*酮化合物
TWI614238B (zh) 2012-09-21 2018-02-11 必治妥美雅史谷比公司 雙(氟烷基)-1,4-苯并二氮呯酮化合物及其前藥
WO2014047397A1 (en) 2012-09-21 2014-03-27 Bristol-Myers Squibb Company Fluoroalkyl and fluorocycloalkyl 1,4-benzodiazepinone compounds as notch|inhibitors
JP2016515625A (ja) * 2013-04-04 2016-05-30 ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company 増殖性疾患を治療するための併用療法
WO2015095116A1 (en) * 2013-12-17 2015-06-25 Rush University Medical Center Compositions and methods for treating diabetic nephropathy
US20170314027A1 (en) 2014-08-06 2017-11-02 Massachusetts Eye And Ear Infirmary Increasing atoh1 life to drive sensorineural hair cell differentiantion
WO2016069906A1 (en) 2014-10-29 2016-05-06 Massachusetts Eye And Ear Infirmary Efficient delivery of therapeutic molecules to cells of the inner ear
US11185536B2 (en) 2015-12-04 2021-11-30 Massachusetts Eye And Ear Infirmary Treatment of hearing loss by inhibition of casein kinase 1
KR20180117628A (ko) 2016-01-29 2018-10-29 매사추세츠 아이 앤드 이어 인퍼머리 내이 지지 세포의 확장 및 분화 및 그의 사용 방법
WO2017180385A1 (en) 2016-04-12 2017-10-19 Eli Lilly And Company Combination therapy with notch and pi3k/mtor inhibitors for use in treating cancer
KR102362222B1 (ko) 2016-05-16 2022-02-11 더 제너럴 하스피탈 코포레이션 폐 상피 공학에서 인간 기도 줄기 세포
JP7194022B2 (ja) 2016-05-20 2022-12-21 イーライ リリー アンド カンパニー Notch阻害剤とPD-1またはPD-L1阻害剤との併用療法
AU2017376109A1 (en) 2016-12-16 2019-07-11 Pipeline Therapeutics, Inc. Methods of treating cochlear synaptopathy
MA50564A (fr) 2017-11-06 2020-09-16 Hutchinson Fred Cancer Res Association d'une thérapie cellulaire et d'un inhibiteur de gamma secrétase
KR102094442B1 (ko) 2018-06-28 2020-03-27 성균관대학교산학협력단 알쯔하이머성 치매의 예방 또는 치료용 물질 및 이를 포함하는 조성물
WO2022067185A1 (en) * 2020-09-27 2022-03-31 Veru Inc. Methods of treating prostate cancer with minimal side effects
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US6012A (en) * 1849-01-09 Lithographing co
KR100838852B1 (ko) * 2003-09-09 2008-06-16 에프. 호프만-라 로슈 아게 감마-세크리테이즈의 활성을 차단하는 말론아미드 유도체
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JP2008530232A (ja) * 2005-02-15 2008-08-07 ノバルティス ヴァクシンズ アンド ダイアグノスティクス インコーポレイテッド 化学療法剤、il−2および場合により抗cd20抗体の組み合わせを使用してリンパ腫を処置する方法
EP1888051A2 (en) * 2005-05-17 2008-02-20 MERCK SHARP & DOHME LTD. Sulphonamido-substituted cyclohexyl sulphones for treatment of cancer
US20080058316A1 (en) * 2006-02-27 2008-03-06 The Johns Hopkins University Cancer treatment with gama-secretase inhibitors

Also Published As

Publication number Publication date
JP2014221772A (ja) 2014-11-27
US20090181944A1 (en) 2009-07-16
CA2710913A1 (en) 2009-07-16
WO2009087130A1 (en) 2009-07-16
JP2013241443A (ja) 2013-12-05
CR11510A (es) 2010-09-13
EP2244713A1 (en) 2010-11-03
RU2010133489A (ru) 2012-02-20
MA33076B1 (fr) 2012-03-01
TW200936139A (en) 2009-09-01
JP5612482B2 (ja) 2014-10-22
KR20100101624A (ko) 2010-09-17
CN101909633B (zh) 2012-05-30
JP2011509273A (ja) 2011-03-24
CL2009000040A1 (es) 2010-02-12
KR20140007979A (ko) 2014-01-20
IL206361A0 (en) 2010-12-30
AU2009203776A1 (en) 2009-07-16
ZA201004859B (en) 2011-03-30
BRPI0906831A2 (pt) 2019-09-24
CN101909633A (zh) 2010-12-08

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