AR072444A1 - Metodo para confirmar la actividad antioxidante de una composicion topica - Google Patents
Metodo para confirmar la actividad antioxidante de una composicion topicaInfo
- Publication number
- AR072444A1 AR072444A1 ARP090100208A ARP090100208A AR072444A1 AR 072444 A1 AR072444 A1 AR 072444A1 AR P090100208 A ARP090100208 A AR P090100208A AR P090100208 A ARP090100208 A AR P090100208A AR 072444 A1 AR072444 A1 AR 072444A1
- Authority
- AR
- Argentina
- Prior art keywords
- extract
- composition according
- composition
- skin
- induced
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 13
- 230000003078 antioxidant effect Effects 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 5
- 230000000699 topical effect Effects 0.000 title abstract 3
- -1 lipid hydroperoxides Chemical class 0.000 abstract 8
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 abstract 7
- 241000219095 Vitis Species 0.000 abstract 6
- 150000001875 compounds Chemical class 0.000 abstract 6
- 239000000284 extract Substances 0.000 abstract 6
- 210000003491 skin Anatomy 0.000 abstract 5
- 230000005855 radiation Effects 0.000 abstract 4
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 3
- OFOBLEOULBTSOW-UHFFFAOYSA-L Malonate Chemical compound [O-]C(=O)CC([O-])=O OFOBLEOULBTSOW-UHFFFAOYSA-L 0.000 abstract 3
- 229930003427 Vitamin E Natural products 0.000 abstract 3
- 235000009392 Vitis Nutrition 0.000 abstract 3
- 235000009754 Vitis X bourquina Nutrition 0.000 abstract 3
- 235000012333 Vitis X labruscana Nutrition 0.000 abstract 3
- 235000014787 Vitis vinifera Nutrition 0.000 abstract 3
- 239000003963 antioxidant agent Substances 0.000 abstract 3
- 235000006708 antioxidants Nutrition 0.000 abstract 3
- 230000015572 biosynthetic process Effects 0.000 abstract 3
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 abstract 3
- 230000003244 pro-oxidative effect Effects 0.000 abstract 3
- 235000019165 vitamin E Nutrition 0.000 abstract 3
- 229940046009 vitamin E Drugs 0.000 abstract 3
- 239000011709 vitamin E Substances 0.000 abstract 3
- ALYNCZNDIQEVRV-UHFFFAOYSA-N 4-aminobenzoic acid Chemical compound NC1=CC=C(C(O)=O)C=C1 ALYNCZNDIQEVRV-UHFFFAOYSA-N 0.000 abstract 2
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 abstract 2
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 abstract 2
- 210000002615 epidermis Anatomy 0.000 abstract 2
- 230000005764 inhibitory process Effects 0.000 abstract 2
- 230000003859 lipid peroxidation Effects 0.000 abstract 2
- VAMXMNNIEUEQDV-UHFFFAOYSA-N methyl anthranilate Chemical compound COC(=O)C1=CC=CC=C1N VAMXMNNIEUEQDV-UHFFFAOYSA-N 0.000 abstract 2
- 239000000516 sunscreening agent Substances 0.000 abstract 2
- HEOCBCNFKCOKBX-RELGSGGGSA-N (1s,2e,4r)-4,7,7-trimethyl-2-[(4-methylphenyl)methylidene]bicyclo[2.2.1]heptan-3-one Chemical compound C1=CC(C)=CC=C1\C=C/1C(=O)[C@]2(C)CC[C@H]\1C2(C)C HEOCBCNFKCOKBX-RELGSGGGSA-N 0.000 abstract 1
- AFDXODALSZRGIH-QPJJXVBHSA-N (E)-3-(4-methoxyphenyl)prop-2-enoic acid Chemical compound COC1=CC=C(\C=C\C(O)=O)C=C1 AFDXODALSZRGIH-QPJJXVBHSA-N 0.000 abstract 1
- JYEUMXHLPRZUAT-UHFFFAOYSA-N 1,2,3-triazine Chemical compound C1=CN=NN=C1 JYEUMXHLPRZUAT-UHFFFAOYSA-N 0.000 abstract 1
- VHWSRELATOUTAG-UHFFFAOYSA-N 2,3-dihydroxypropyl 2-aminobenzoate Chemical compound NC1=CC=CC=C1C(=O)OCC(O)CO VHWSRELATOUTAG-UHFFFAOYSA-N 0.000 abstract 1
- ZFFMLCVRJBZUDZ-UHFFFAOYSA-N 2,3-dimethylbutane Chemical group CC(C)C(C)C ZFFMLCVRJBZUDZ-UHFFFAOYSA-N 0.000 abstract 1
- WSSJONWNBBTCMG-UHFFFAOYSA-N 2-hydroxybenzoic acid (3,3,5-trimethylcyclohexyl) ester Chemical compound C1C(C)(C)CC(C)CC1OC(=O)C1=CC=CC=C1O WSSJONWNBBTCMG-UHFFFAOYSA-N 0.000 abstract 1
- ZUYVPAKYYMBQBT-UHFFFAOYSA-N 3,4-diethyl-2-hexoxyphenol Chemical compound CCCCCCOC1=C(O)C=CC(CC)=C1CC ZUYVPAKYYMBQBT-UHFFFAOYSA-N 0.000 abstract 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 abstract 1
- 244000068988 Glycine max Species 0.000 abstract 1
- 235000010469 Glycine max Nutrition 0.000 abstract 1
- 108010059332 Photosynthetic Reaction Center Complex Proteins Proteins 0.000 abstract 1
- 244000181025 Rosa gallica Species 0.000 abstract 1
- 235000000533 Rosa gallica Nutrition 0.000 abstract 1
- 244000178231 Rosmarinus officinalis Species 0.000 abstract 1
- 241000589596 Thermus Species 0.000 abstract 1
- 241000219793 Trifolium Species 0.000 abstract 1
- 241001464837 Viridiplantae Species 0.000 abstract 1
- WYWZRNAHINYAEF-AWEZNQCLSA-N [(2s)-2-ethylhexyl] 4-(dimethylamino)benzoate Chemical compound CCCC[C@H](CC)COC(=O)C1=CC=C(N(C)C)C=C1 WYWZRNAHINYAEF-AWEZNQCLSA-N 0.000 abstract 1
- 229960005193 avobenzone Drugs 0.000 abstract 1
- XNEFYCZVKIDDMS-UHFFFAOYSA-N avobenzone Chemical compound C1=CC(OC)=CC=C1C(=O)CC(=O)C1=CC=C(C(C)(C)C)C=C1 XNEFYCZVKIDDMS-UHFFFAOYSA-N 0.000 abstract 1
- 230000000975 bioactive effect Effects 0.000 abstract 1
- YEAYGXLRPMKZBP-KQGICBIGSA-N bis(2-hydroxyethyl)azanium;(e)-3-(4-methoxyphenyl)prop-2-enoate Chemical compound OCCNCCO.COC1=CC=C(\C=C\C(O)=O)C=C1 YEAYGXLRPMKZBP-KQGICBIGSA-N 0.000 abstract 1
- FQUNFJULCYSSOP-UHFFFAOYSA-N bisoctrizole Chemical compound N1=C2C=CC=CC2=NN1C1=CC(C(C)(C)CC(C)(C)C)=CC(CC=2C(=C(C=C(C=2)C(C)(C)CC(C)(C)C)N2N=C3C=CC=CC3=N2)O)=C1O FQUNFJULCYSSOP-UHFFFAOYSA-N 0.000 abstract 1
- 229960001063 cinoxate Drugs 0.000 abstract 1
- CMDKPGRTAQVGFQ-RMKNXTFCSA-N cinoxate Chemical compound CCOCCOC(=O)\C=C\C1=CC=C(OC)C=C1 CMDKPGRTAQVGFQ-RMKNXTFCSA-N 0.000 abstract 1
- FDATWRLUYRHCJE-UHFFFAOYSA-N diethylamino hydroxybenzoyl hexyl benzoate Chemical compound CCCCCCOC(=O)C1=CC=CC=C1C(=O)C1=CC=C(N(CC)CC)C=C1O FDATWRLUYRHCJE-UHFFFAOYSA-N 0.000 abstract 1
- 229960001630 diethylamino hydroxybenzoyl hexyl benzoate Drugs 0.000 abstract 1
- GLCJMPWWQKKJQZ-UHFFFAOYSA-L disodium;2-[4-(4,6-disulfonato-1h-benzimidazol-2-yl)phenyl]-1h-benzimidazole-4,6-disulfonate;hydron Chemical compound [Na+].[Na+].C1=C(S(O)(=O)=O)C=C2NC(C3=CC=C(C=C3)C3=NC4=C(C=C(C=C4N3)S(=O)(=O)O)S([O-])(=O)=O)=NC2=C1S([O-])(=O)=O GLCJMPWWQKKJQZ-UHFFFAOYSA-L 0.000 abstract 1
- HUVYTMDMDZRHBN-UHFFFAOYSA-N drometrizole trisiloxane Chemical compound C[Si](C)(C)O[Si](C)(O[Si](C)(C)C)CC(C)CC1=CC(C)=CC(N2N=C3C=CC=CC3=N2)=C1O HUVYTMDMDZRHBN-UHFFFAOYSA-N 0.000 abstract 1
- 235000013399 edible fruits Nutrition 0.000 abstract 1
- UVCJGUGAGLDPAA-UHFFFAOYSA-N ensulizole Chemical compound N1C2=CC(S(=O)(=O)O)=CC=C2N=C1C1=CC=CC=C1 UVCJGUGAGLDPAA-UHFFFAOYSA-N 0.000 abstract 1
- 229960000655 ensulizole Drugs 0.000 abstract 1
- 229960004697 enzacamene Drugs 0.000 abstract 1
- CBZHHQOZZQEZNJ-UHFFFAOYSA-N ethyl 4-[bis(2-hydroxypropyl)amino]benzoate Chemical compound CCOC(=O)C1=CC=C(N(CC(C)O)CC(C)O)C=C1 CBZHHQOZZQEZNJ-UHFFFAOYSA-N 0.000 abstract 1
- 238000000855 fermentation Methods 0.000 abstract 1
- 230000004151 fermentation Effects 0.000 abstract 1
- 229940094952 green tea extract Drugs 0.000 abstract 1
- 235000020688 green tea extract Nutrition 0.000 abstract 1
- 229960004881 homosalate Drugs 0.000 abstract 1
- 229940102398 methyl anthranilate Drugs 0.000 abstract 1
- 229960003921 octisalate Drugs 0.000 abstract 1
- WCJLCOAEJIHPCW-UHFFFAOYSA-N octyl 2-hydroxybenzoate Chemical compound CCCCCCCCOC(=O)C1=CC=CC=C1O WCJLCOAEJIHPCW-UHFFFAOYSA-N 0.000 abstract 1
- 239000008601 oleoresin Substances 0.000 abstract 1
- DXGLGDHPHMLXJC-UHFFFAOYSA-N oxybenzone Chemical compound OC1=CC(OC)=CC=C1C(=O)C1=CC=CC=C1 DXGLGDHPHMLXJC-UHFFFAOYSA-N 0.000 abstract 1
- 229960001173 oxybenzone Drugs 0.000 abstract 1
- 229960002638 padimate o Drugs 0.000 abstract 1
- 229940016134 pikea robusta extract Drugs 0.000 abstract 1
- 229940068196 placebo Drugs 0.000 abstract 1
- 239000000902 placebo Substances 0.000 abstract 1
- 229920001296 polysiloxane Polymers 0.000 abstract 1
- 239000003642 reactive oxygen metabolite Substances 0.000 abstract 1
- 230000006950 reactive oxygen species formation Effects 0.000 abstract 1
- CXVGEDCSTKKODG-UHFFFAOYSA-N sulisobenzone Chemical compound C1=C(S(O)(=O)=O)C(OC)=CC(O)=C1C(=O)C1=CC=CC=C1 CXVGEDCSTKKODG-UHFFFAOYSA-N 0.000 abstract 1
- 229960000368 sulisobenzone Drugs 0.000 abstract 1
- 239000004408 titanium dioxide Substances 0.000 abstract 1
- 229960005196 titanium dioxide Drugs 0.000 abstract 1
- 229930003799 tocopherol Natural products 0.000 abstract 1
- 229960001295 tocopherol Drugs 0.000 abstract 1
- 239000011732 tocopherol Substances 0.000 abstract 1
- 235000010384 tocopherol Nutrition 0.000 abstract 1
- UEVAMYPIMMOEFW-UHFFFAOYSA-N trolamine salicylate Chemical compound OCCN(CCO)CCO.OC(=O)C1=CC=CC=C1O UEVAMYPIMMOEFW-UHFFFAOYSA-N 0.000 abstract 1
- 229940030300 trolamine salicylate Drugs 0.000 abstract 1
- 239000011787 zinc oxide Substances 0.000 abstract 1
- 229960001296 zinc oxide Drugs 0.000 abstract 1
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/025—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
- G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
- A61K2800/522—Antioxidants; Radical scavengers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Cell Biology (AREA)
- Birds (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Dermatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Mycology (AREA)
- Botany (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
Abstract
Métodos para confirmar actividad antioxidante de una composicion formulada para aplicacion topica a la piel. Métodos para probar una composicion para la capacidad de inhibir la formacion de peroxidacion de lípidos inducida por radiacion ultravioleta en la piel como la formacion de especies de oxígeno reactivo inducido por radiacion ultravioleta en la epidermis. Composiciones. Métodos para tratar y prevenir fotodano de la piel. Reivindicacion 4: El método de conformidad con la reivindicacion 2, caracterizado porque la determinacion de la inhibicion de formacion de hidroperoxidos de lípidos en la piel inducida por UVR comprende determinar el porcentaje de inhibicion de hidroperoxidos de lípidos del compuesto en comparacion con el placebo. Reivindicacion 9: La composicion de conformidad con la reivindicacion 8, caracterizada porque además comprende al menos un agente activo de filtro solar. Reivindicacion 10: La composicion de conformidad con la reivindicacion 9, caracterizada porque el agente activo de filtro solar se elige del grupo que consiste de ácido para-aminobenzoico, avobenzona, cinoxato, dioxibenzona, homosalato, antranilato de metilo, salicitato de octilo, oxibenzona, padimato O, ácido fenilbenzimidazol sulfonico, sulisobenzona, salicilato de trolamina, dioxido de titanio, oxido de zinc, metoxicinamato de dietanolamina, trioleato de digaloi, etil dihidroxipropilo PABA, aminobenzoato de glicerilo, lawsona con dihidroxiacetona, petrolato rojo, triazona de etilhexilo, butamido triazona de dioctilo, bencilideno malonato polisiloxano, ácido tereftalilideno dicanfor sulfonico, tetrasulfonato de disodio fenil dibenzimidazol, benzoato de dietilamino hidroxibenzoil hexil, bis dietilamino hidroxibenzoil benzoato, bis benzoxazoilfenil etilhexilimino triazina, trisiloxano de drometrizol, metilen bis-benzotriazolil tetrametilbutilfenol, y bis-etilhexiloxifenol metoxifeniltriazina, 4-metilbencilidencanfor, e isopetil 4-metoxicinamato y mezclas de los mismos. Reivindicacion 13: La composicion de conformidad con la reivindicacion 8, caracterizada porque comprende como un antioxidante Vitamina E y al menos un compuesto antioxidante adicional. Reivindicacion 16: La composicion de conformidad con la reivindicacion 13, caracterizada porque al menos un compuesto antioxidante adicional se elige del grupo que consiste de malonato de dietilhexil siringlideno, malonato de diisopropil vanilideno, tetrahidrocurcumenoides, fermentado de zimbiozona de fríjol de soya, extracto de trébol rojo, extracto de semilla de Vitis vinífera (uva) / Clase B, extracto de té verde, extracto de Pikea robusta, tocoferol (y) extracto de semilla de Vitis vinífera (uva), extracto de semilla de Vitis vinífera (uva) / Clase A, extracto de fruta Phylanthus emblica y combinaciones de los mismos. Reivindicacion 17: Una composicion para aplicacion topica, caracterizada porque la composicion comprende Vitamina E y al menos un compuesto pro-oxidante, en donde la combinacion de Vitamina E y el compuesto pro-oxidante inhibe substancialmente la formacion tanto de peroxidacion de lípido en la piel inducida por radiacion ultravioleta como de especies de oxígeno reactivo inducido por radiacion ultravioleta en la epidermis. Reivindicacion 18: La composicion de conformidad con la reivindicacion 17, caracterizado porque al menos un compuesto pro-oxidante se elige del grupo que consiste de Oleoresina de romero officinalis, extracto de Rosa Gallica, complejo fotosintético bioactivo de plantas verdes, fermentado de Thermus Thermophillus, ergotiotaina y combinaciones de los mismos. Reivindicacion 21: La composicion de conformidad con la reivindicacion 17, caracterizada porque comprende además malonato de dietilhexil siringlideno.
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2009
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- 2009-01-21 JP JP2010544395A patent/JP2011511770A/ja active Pending
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- 2009-01-21 US US12/357,006 patent/US20090189090A1/en not_active Abandoned
- 2009-01-21 EP EP09703733.7A patent/EP2247949B1/en active Active
- 2009-01-21 CN CN2009801030355A patent/CN101925816A/zh active Pending
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2012
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2015
- 2015-04-28 JP JP2015091654A patent/JP6154426B2/ja not_active Expired - Fee Related
- 2015-08-04 US US14/818,212 patent/US10241121B2/en not_active Expired - Fee Related
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2019
- 2019-03-20 US US16/358,862 patent/US20190285657A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
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| US20190285657A1 (en) | 2019-09-19 |
| JP6154426B2 (ja) | 2017-06-28 |
| CA2711270C (en) | 2017-02-28 |
| PT2247949T (pt) | 2017-08-25 |
| JP2015163624A (ja) | 2015-09-10 |
| US20160033538A1 (en) | 2016-02-04 |
| US10241121B2 (en) | 2019-03-26 |
| CN103394088B (zh) | 2017-01-18 |
| JP2011511770A (ja) | 2011-04-14 |
| US20130101515A1 (en) | 2013-04-25 |
| CN103394088A (zh) | 2013-11-20 |
| BRPI0908478A2 (pt) | 2015-08-18 |
| EP2247949B1 (en) | 2017-05-24 |
| US20090189090A1 (en) | 2009-07-30 |
| CA2711270A1 (en) | 2009-07-30 |
| AU2009206489B2 (en) | 2014-10-02 |
| EP2247949A2 (en) | 2010-11-10 |
| MX2010008065A (es) | 2010-10-20 |
| US9096882B2 (en) | 2015-08-04 |
| WO2009094374A2 (en) | 2009-07-30 |
| CN101925816A (zh) | 2010-12-22 |
| AU2009206489A1 (en) | 2009-07-30 |
| WO2009094374A3 (en) | 2009-09-17 |
| ES2637516T3 (es) | 2017-10-13 |
| HRP20171215T1 (hr) | 2017-12-15 |
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