AR071363A1 - Derivados de sulfonamida sustituida y su empleo en medicamentos para el tratamiento de enfermedades mediadas por receptores b1r. - Google Patents
Derivados de sulfonamida sustituida y su empleo en medicamentos para el tratamiento de enfermedades mediadas por receptores b1r.Info
- Publication number
- AR071363A1 AR071363A1 ARP090101258A ARP090101258A AR071363A1 AR 071363 A1 AR071363 A1 AR 071363A1 AR P090101258 A ARP090101258 A AR P090101258A AR P090101258 A ARP090101258 A AR P090101258A AR 071363 A1 AR071363 A1 AR 071363A1
- Authority
- AR
- Argentina
- Prior art keywords
- aryl
- heteroaryl
- cycloalkyl
- group
- alkyl
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 3
- 229940124530 sulfonamide Drugs 0.000 title abstract 3
- 150000003456 sulfonamides Chemical class 0.000 title abstract 3
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 230000001404 mediated effect Effects 0.000 title 1
- 125000003118 aryl group Chemical group 0.000 abstract 19
- 125000001072 heteroaryl group Chemical group 0.000 abstract 18
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 abstract 11
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 8
- 125000002947 alkylene group Chemical group 0.000 abstract 8
- 125000005842 heteroatom Chemical group 0.000 abstract 4
- 125000003161 (C1-C6) alkylene group Chemical group 0.000 abstract 3
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 abstract 3
- 125000003601 C2-C6 alkynyl group Chemical group 0.000 abstract 3
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 229940079593 drug Drugs 0.000 abstract 2
- -1 halide anion Chemical class 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 238000002483 medication Methods 0.000 abstract 2
- HFFXLYHRNRKAPM-UHFFFAOYSA-N 2,4,5-trichloro-n-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide Chemical class O1C(C)=CC(NS(=O)(=O)C=2C(=CC(Cl)=C(Cl)C=2)Cl)=N1 HFFXLYHRNRKAPM-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 abstract 1
- 125000000592 heterocycloalkyl group Chemical group 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Child & Adolescent Psychology (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
Derivados de sulfonamidas, los procesos para su elaboracion, los medicamentos que contienen estos compuestos y el uso de los derivados de sulfonamidas para la elaboracion de medicamentos. Reivindicacion 1: Derivado de sulfonamida sustituida de la formula general (1) en donde m es 0, 1 o 2; n es 1 o 2; o es 0, 1 o 2; p es 0, 1 o 2; q es 0, 1, 2 o 3; r es 0, 1 o 2, siempre que q + r no sea mayor que 3; v es 0 o 1; w es 0 o 1; siempre que cuando v sea 0, w también sea 0; An- significa anion de halogenuro; Q es un enlace simple, -O- o -CH2; R1 es arilo o heteroarilo; o un arilo o heteroarilo unido mediante un grupo alquileno C1-3; R2 y R3 se definen conforme a las descripciones (i) y (ii) siguientes: (i) R2 es H, alquilo C1-6, cicloalquilo C3-8, carbociclilo bicíclico de 8 a 12 elementos, arilo o heteroarilo, o un cicloalquilo C3-8, un carbociclilo bicíclico de 8 a 12 miembros, CH(arilo)2, arilo o heteroarilo unidos mediante un grupo cicloalquilo C3-8 o un grupo alquileno C2-6 o un grupo alquinilo C2-6; y R3 es H, alquilo C1-6, arilo o heteroarilo, o un arilo o heteroarilo unido mediante un grupo alquileno C2-6, alquenilo C2-6 o un grupo alquinilo C2-6; o (ii) R2 y R3 en forma conjunta con el grupo -N-(CH-)- forman un heterociclo, el cual puede unirse con un residuo de arilo o heteroarilo, en donde el heterociclo es saturado o al menos no saturado en forma simple, pero no es aromático, tiene 4, 5, 6 o 7 elementos, junto con el heteroátomo de N, al cual está unido el residuo R2, al menos puede contener otro heteroátomo o un grupo de heteroátomos seleccionado a partir del grupo formado por N, NR7, O, S, S=O o S(=O)2; en donde, el residuo R7 representa H, alquilo C1-6, -C(=O)-R8, cicloalquilo C3-8, arilo, heteroarilo, o un cicloalquilo C3-8, arilo o heteroarilo unido mediante un grupo alquileno C1-3, y R8 significa alquilo C1-6, cicloalquilo C3-8, arilo, heteroarilo o un cicloalquilo C3-8, arilo o heteroarilo unido mediante un grupo alquileno C1-3; R4 es arilo, heteroarilo o un arilo o heteroarilo unido mediante un grupo alquileno C1-6; R5 y R6 de manera independiente son H, alquilo C1-6, cicloalquilo C3-8, o un cicloalquilo C3-8 unido por un grupo alquileno C1-3, en donde R5 y R6 en forma conjunta, no representan H al mismo tiempo; o R5 y R6 en forma conjunta representan un heteroarilo sustituido o no sustituido de 5 o 6 elementos, el cual junto con el átomo de N, al cual R5 y R6 están unidos, puede contener incluso al menos otro heteroátomo del grupo N, O o S; o R5 y R6, en forma conjunta, representan un grupo seleccionado a partir de -(CH2)d- o -(CH2)e-X-(CH2)f-, en donde d significa 2, 3, 4, 5 o 6 y e y f, en forma independiente, significan 1, 2 o 3, siempre que e + f no sean mayor a 5; y X representa NR12, CF2, O, S, S=O o S(=O)2, y en donde R12 es alquilo C1-6, cicloalquilo C3-8, arilo, heteroarilo o un cicloalquilo C3-8, arilo, heteroarilo unido mediante un grupo alquileno C1-3; R20 es alquilo C1-6, ciclopropilo, un cicloalquilo, arilo o heteroarilo unido mediante un grupo alquileno C1-3, o =O, siempre que R20 sea =O, w sea 0; y en donde los residuos mencionados pueden ser alquilo C1-6, alquileno C1-6, alquenilo C2-6, alquinilo C2-6, cicloalquilo C3-8, heterocicloalquilo C3-8, carbociclilo bicíclico de 8 a 12 elementos, arilo y heteroarilo, ya sea no sustituido o sustituido en forma simple o multiple con residuos iguales o diferentes y los residuos indicados anteriormente pueden ser alquilo C1-6, alquileno C1-6, alquenilo C2-6 y alquinilo, ya sea ramificados o no ramificados; en forma de racemato; los enantiomeros, diastereomeros, mezclas de enantiomeros o diastereomeros o un enantiomero o diastereomero, los ácidos fisiologicamente compatibles con las bases y/o sales.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08006957 | 2008-04-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR071363A1 true AR071363A1 (es) | 2010-06-16 |
Family
ID=39967424
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP090101258A AR071363A1 (es) | 2008-04-08 | 2009-04-08 | Derivados de sulfonamida sustituida y su empleo en medicamentos para el tratamiento de enfermedades mediadas por receptores b1r. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8318769B2 (es) |
| EP (1) | EP2262792A1 (es) |
| JP (1) | JP2011517459A (es) |
| CN (1) | CN102056919B (es) |
| AR (1) | AR071363A1 (es) |
| AU (1) | AU2009235634B8 (es) |
| CA (1) | CA2720793A1 (es) |
| CL (1) | CL2009000851A1 (es) |
| IL (1) | IL208519A0 (es) |
| MX (1) | MX2010011095A (es) |
| PE (1) | PE20091782A1 (es) |
| RU (1) | RU2503674C2 (es) |
| TW (1) | TW200948801A (es) |
| WO (1) | WO2009124733A1 (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2007304475B2 (en) * | 2006-09-29 | 2012-07-26 | Grunenthal Gmbh | Substituted sulfonamide derivatives |
| US8404741B2 (en) * | 2010-02-19 | 2013-03-26 | Bristol-Myers Squibb Company | Glycine chroman-6-sulfonamides for use as inhibitors of diacylglycerol lipase |
| HUP1000598A2 (en) | 2010-11-05 | 2012-09-28 | Richter Gedeon Nyrt | Indole derivatives |
| JP2014159375A (ja) * | 2011-06-15 | 2014-09-04 | Takeda Chem Ind Ltd | アゼパン化合物 |
| CN107266378B (zh) * | 2016-04-06 | 2020-08-21 | 南开大学 | 含有磺酰基结构三嗪酮衍生物及其制备方法和在杀虫、杀菌方面的应用 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2743562B1 (fr) * | 1996-01-11 | 1998-04-03 | Sanofi Sa | Derives de n-(arylsulfonyl) aminoacides, leur preparation, les compositions pharmaceutiques en contenant |
| US5932576A (en) * | 1997-05-22 | 1999-08-03 | G. D. Searle & Company | 3(5)-heteroaryl substituted pyrazoles as p38 kinase inhibitors |
| FR2822827B1 (fr) * | 2001-03-28 | 2003-05-16 | Sanofi Synthelabo | Nouveaux derives de n-(arylsulfonyl) beta-aminoacides comportant un groupe aminomethyle substitue, leur procede de preparation et les compositions pharmaceutiques en contenant |
| ES2327338T3 (es) | 2003-03-25 | 2009-10-28 | Laboratoires Fournier Sa | Derivados de bencenosulfonamida, su procedimiento de preparacion y su utilizacion para el tratamiento del dolor. |
| CA2521937A1 (en) * | 2003-04-10 | 2004-10-28 | Amgen, Inc. | Bicyclic compounds having bradykinin receptors affinity and pharmaceutical compositions thereof |
| CA2522084A1 (en) * | 2003-04-10 | 2004-10-28 | Amgen Inc. | Cyclic amine derivatives and their use in the treatment of inflammation-related disorders mediated by bradykinin |
| WO2007140383A2 (en) | 2006-05-30 | 2007-12-06 | Neurogen Corporation | Spirocyclic sulfonamides and related compounds |
| DE102006039003A1 (de) | 2006-08-19 | 2008-02-21 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Verbindungen |
| WO2008024692A1 (en) | 2006-08-23 | 2008-02-28 | Neurogen Corporation | N-oxide aryl sulfones and sulfoxides |
| AU2007304475B2 (en) * | 2006-09-29 | 2012-07-26 | Grunenthal Gmbh | Substituted sulfonamide derivatives |
| WO2008046573A1 (de) * | 2006-10-16 | 2008-04-24 | Grünenthal GmbH | Substituierte sulfonamid-derivate als bradykinin 1 rezeptor modulatoren |
| DE102007020492A1 (de) * | 2007-04-30 | 2008-11-06 | Grünenthal GmbH | Substituierte Sulfonamid-Derivate |
| DE102007020493A1 (de) * | 2007-04-30 | 2008-11-06 | Grünenthal GmbH | Substituierte Amid-Derivate |
| TW200940528A (en) * | 2008-03-05 | 2009-10-01 | Gruenenthal Gmbh | Substituted sulfonamide derivatives |
| TW200940523A (en) * | 2008-03-17 | 2009-10-01 | Gruenenthal Gmbh | Substituted sulfonamide derivatives |
| CA2720735A1 (en) * | 2008-04-08 | 2009-10-15 | Gruenenthal Gmbh | Substituted sulfonamide derivatives |
| AU2010204118B2 (en) * | 2009-01-12 | 2012-12-20 | Icagen, Inc. | Sulfonamide derivatives |
-
2009
- 2009-04-08 EP EP09730791A patent/EP2262792A1/de not_active Withdrawn
- 2009-04-08 JP JP2011503376A patent/JP2011517459A/ja active Pending
- 2009-04-08 CN CN200980121445.2A patent/CN102056919B/zh not_active Expired - Fee Related
- 2009-04-08 WO PCT/EP2009/002578 patent/WO2009124733A1/de not_active Ceased
- 2009-04-08 US US12/420,488 patent/US8318769B2/en not_active Expired - Fee Related
- 2009-04-08 AU AU2009235634A patent/AU2009235634B8/en not_active Ceased
- 2009-04-08 AR ARP090101258A patent/AR071363A1/es not_active Application Discontinuation
- 2009-04-08 PE PE2009000496A patent/PE20091782A1/es not_active Application Discontinuation
- 2009-04-08 CA CA2720793A patent/CA2720793A1/en not_active Abandoned
- 2009-04-08 MX MX2010011095A patent/MX2010011095A/es active IP Right Grant
- 2009-04-08 TW TW098111605A patent/TW200948801A/zh unknown
- 2009-04-08 CL CL2009000851A patent/CL2009000851A1/es unknown
- 2009-04-08 RU RU2010145013/04A patent/RU2503674C2/ru not_active IP Right Cessation
-
2010
- 2010-10-06 IL IL208519A patent/IL208519A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2011517459A (ja) | 2011-06-09 |
| RU2503674C2 (ru) | 2014-01-10 |
| AU2009235634A1 (en) | 2009-10-15 |
| CA2720793A1 (en) | 2009-10-15 |
| CN102056919A (zh) | 2011-05-11 |
| PE20091782A1 (es) | 2009-11-15 |
| EP2262792A1 (de) | 2010-12-22 |
| TW200948801A (en) | 2009-12-01 |
| IL208519A0 (en) | 2010-12-30 |
| CN102056919B (zh) | 2014-03-12 |
| AU2009235634B8 (en) | 2013-05-23 |
| AU2009235634B2 (en) | 2013-04-18 |
| CL2009000851A1 (es) | 2009-07-17 |
| WO2009124733A1 (de) | 2009-10-15 |
| WO2009124733A8 (de) | 2010-11-18 |
| US8318769B2 (en) | 2012-11-27 |
| MX2010011095A (es) | 2010-11-05 |
| US20090264400A1 (en) | 2009-10-22 |
| RU2010145013A (ru) | 2012-05-20 |
| AU2009235634A8 (en) | 2013-05-23 |
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