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AR070864A1 - Uso de inhibidores peptidicos de la via de transduccion de senales de jnk para el tratamiento de varias enfermedades - Google Patents

Uso de inhibidores peptidicos de la via de transduccion de senales de jnk para el tratamiento de varias enfermedades

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Publication number
AR070864A1
AR070864A1 ARP090100843A AR070864A1 AR 070864 A1 AR070864 A1 AR 070864A1 AR P090100843 A ARP090100843 A AR P090100843A AR 070864 A1 AR070864 A1 AR 070864A1
Authority
AR
Argentina
Prior art keywords
diseases
disorders
treatment
various diseases
signal transduction
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Application number
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English (en)
Original Assignee
Xigen Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Xigen Sa filed Critical Xigen Sa
Publication of AR070864A1 publication Critical patent/AR070864A1/es

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Abstract

Uso de inhibidores de proteín quinasa y mas específicamente uso de inhibidores de la quinasa amino terminal c-Jun, secuencias inhibidoras de JNK, péptidos quiméricos o de ácidos nucleicos que codifican los mismos así como también composiciones farmacéuticas que los contienen, para el tratamiento de varias enfermedades o trastornos que están fuertemente relacionados con la senalizacion de JNK, donde estas enfermedades o trastornos están seleccionados entre trastornos autoinmunitarios, trastornos cardiovasculares, trastornos cancerosos, diabetes, incluyendo diabetes de tipo 1 o de tipo 2, enfermedades inflamatorias, pérdida de cabella, incluyendo Alopecia areata, enfermedades del pulmon, enfermedades neuronales o neurodegenerativas, enfermedades del hígado, o enfermedades de la columna vertebral, enfermedades del utero, enfermedades infecciosas virales y trastornos depresivos.
ARP090100843 2008-05-30 2009-03-10 Uso de inhibidores peptidicos de la via de transduccion de senales de jnk para el tratamiento de varias enfermedades AR070864A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2008/004341 WO2009143865A1 (en) 2008-05-30 2008-05-30 Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases

Publications (1)

Publication Number Publication Date
AR070864A1 true AR070864A1 (es) 2010-05-12

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ARP090100843 AR070864A1 (es) 2008-05-30 2009-03-10 Uso de inhibidores peptidicos de la via de transduccion de senales de jnk para el tratamiento de varias enfermedades

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US (2) US9006185B2 (es)
EP (6) EP2491942B1 (es)
JP (3) JP5485265B2 (es)
CN (2) CN102112149A (es)
AR (1) AR070864A1 (es)
AU (1) AU2009253346B2 (es)
CA (1) CA2725545A1 (es)
CY (4) CY1114725T1 (es)
DK (5) DK2650008T3 (es)
ES (5) ES2481915T3 (es)
HK (1) HK1221413A1 (es)
HR (1) HRP20150116T1 (es)
HU (1) HUE026798T2 (es)
PL (5) PL2491942T3 (es)
PT (4) PT2489361E (es)
SI (1) SI2650008T1 (es)
WO (2) WO2009143865A1 (es)

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* Cited by examiner, † Cited by third party
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US20040082509A1 (en) 1999-10-12 2004-04-29 Christophe Bonny Cell-permeable peptide inhibitors of the JNK signal transduction pathway
US8183339B1 (en) 1999-10-12 2012-05-22 Xigen S.A. Cell-permeable peptide inhibitors of the JNK signal transduction pathway
US8080517B2 (en) 2005-09-12 2011-12-20 Xigen Sa Cell-permeable peptide inhibitors of the JNK signal transduction pathway
WO2007031098A1 (en) 2005-09-12 2007-03-22 Xigen S.A. Cell-permeable peptide inhibitors of the jnk signal transduction pathway
TWI468417B (zh) 2007-11-30 2015-01-11 Genentech Inc 抗－ｖｅｇｆ抗體
WO2009143865A1 (en) * 2008-05-30 2009-12-03 Xigen S.A. Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases
WO2009143864A1 (en) 2008-05-30 2009-12-03 Xigen S.A. Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of chronic or non-chronic inflammatory digestive diseases
CA2741089A1 (en) 2008-10-22 2010-04-29 Genentech, Inc. Modulation of axon degeneration
WO2010065850A2 (en) * 2008-12-04 2010-06-10 University Of Massachusetts Interleukin 6 and tumor necrosis factor alpha as biomarkers of jnk inhibition
WO2010072228A1 (en) 2008-12-22 2010-07-01 Xigen S.A. Novel transporter constructs and transporter cargo conjugate molecules
WO2011160653A1 (en) 2010-06-21 2011-12-29 Xigen S.A. Novel jnk inhibitor molecules
AU2010362444B2 (en) * 2010-10-14 2015-08-06 Xigen Inflammation Ltd. Use of cell-permeable peptide inhibitors of the JNK signal transduction pathway for the treatment of chronic or non-chronic inflammatory eye diseases
DK2902035T3 (en) * 2010-10-14 2018-09-24 Xigen Inflammation Ltd METHODS FOR TREATING MUSCLE DYROPHY
CN101974083A (zh) * 2010-10-20 2011-02-16 中国医学科学院医学生物学研究所 抗hsv1病毒感染的人源hirrp蛋白分子
WO2013091670A1 (en) * 2011-12-21 2013-06-27 Xigen S.A. Novel jnk inhibitor molecules for treatment of various diseases
WO2014206427A1 (en) * 2013-06-26 2014-12-31 Xigen Inflammation Ltd. New use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases
WO2015197097A1 (en) 2014-06-26 2015-12-30 Xigen Inflammation Ltd. New use for jnk inhibitor molecules for treatment of various diseases
WO2015197098A1 (en) * 2014-06-26 2015-12-30 Xigen Inflammation Ltd. New use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases
WO2014206426A1 (en) * 2013-06-26 2014-12-31 Xigen Inflammation Ltd. New use for jnk inhibitor molecules for treatment of various diseases
WO2015197194A2 (en) * 2014-06-26 2015-12-30 Xigen Inflammation Ltd. New use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases
WO2015197193A2 (en) * 2014-06-26 2015-12-30 Xigen Inflammation Ltd. New use for jnk inhibitor molecules for treatment of various diseases
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