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AR078539A1 - Composiciones que comprenden adyuvante, macrolido y antigeno proteico y procedimientos de uso de las mismas - Google Patents

Composiciones que comprenden adyuvante, macrolido y antigeno proteico y procedimientos de uso de las mismas

Info

Publication number
AR078539A1
AR078539A1 ARP100103632A ARP100103632A AR078539A1 AR 078539 A1 AR078539 A1 AR 078539A1 AR P100103632 A ARP100103632 A AR P100103632A AR P100103632 A ARP100103632 A AR P100103632A AR 078539 A1 AR078539 A1 AR 078539A1
Authority
AR
Argentina
Prior art keywords
compositions
macrolide
procedures
same
protein antigen
Prior art date
Application number
ARP100103632A
Other languages
English (en)
Original Assignee
Wyeth Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Llc filed Critical Wyeth Llc
Publication of AR078539A1 publication Critical patent/AR078539A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0003—Invertebrate antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A61P33/12—Schistosomicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)

Abstract

Composiciones que comprenden un adyuvante oleoso, una lactona macrocíclica eficaz para la prevencion o combate de una infeccion parasitaria en un animal de sangre caliente y una cantidad de inmunizante de al menos un polipéptido inmunogénico y procedimientos de uso de las mismas. Reivindicacion 2: La composicion de la reivindicacion 1, en la que dicha lactona macrocíclica es eficaz para proteger de o combatir helmintiasis en dicho animal de sangre caliente. Reivindicacion 3: La composicion de la reivindicacion 1 o la reivindicacion 2, en la que dicha lactona macrocíclica se selecciona entre un compuesto de milbemicina, un compuesto de avermectina o una combinacion de los mismos.
ARP100103632A 2009-10-07 2010-10-06 Composiciones que comprenden adyuvante, macrolido y antigeno proteico y procedimientos de uso de las mismas AR078539A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24945409P 2009-10-07 2009-10-07

Publications (1)

Publication Number Publication Date
AR078539A1 true AR078539A1 (es) 2011-11-16

Family

ID=43707921

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP100103632A AR078539A1 (es) 2009-10-07 2010-10-06 Composiciones que comprenden adyuvante, macrolido y antigeno proteico y procedimientos de uso de las mismas

Country Status (9)

Country Link
US (1) US20110091559A1 (es)
EP (1) EP2485725A2 (es)
AR (1) AR078539A1 (es)
AU (1) AU2010303741A1 (es)
BR (1) BR112012008185A2 (es)
MX (1) MX2012004133A (es)
TW (1) TW201127398A (es)
UY (1) UY32930A (es)
WO (1) WO2011043962A2 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3028048B1 (en) * 2013-07-31 2018-09-26 BioVentures, LLC Compositions for treating and preventing cancer targeting tumor associated carbohydrate antigens
US10653766B2 (en) 2014-03-12 2020-05-19 Bavarian Nordic A/S Use of oil and water emulsions for increasing B cell responses with modified Vaccinia Ankara virus
GB201714057D0 (en) * 2017-09-01 2017-10-18 Univ College Dublin Nat Univ Of Ireland Dublin A fasciola hepatica antigen and vaccine
CN110898216B (zh) * 2019-12-31 2021-12-03 中国农业科学院兰州兽医研究所 重组旋毛虫硫氧还蛋白过氧化物酶2在制备抗旋毛虫感染疫苗中的应用

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE434277B (sv) 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
US4199569A (en) 1977-10-03 1980-04-22 Merck & Co., Inc. Selective hydrogenation products of C-076 compounds and derivatives thereof
US4389397A (en) 1980-08-04 1983-06-21 Merck & Co., Inc. Solubilization of ivermectin in water
US4853372A (en) 1983-12-22 1989-08-01 Merck & Co., Inc. Non-aqueous ivermectin formulation with improved antiparasitic activity
ES8800986A1 (es) 1985-07-27 1987-12-01 Pfizer Un procedimiento para la produccion de un nuevo derivado de avermectina
US5019589A (en) 1986-09-12 1991-05-28 American Cyanamid Company Δ23 -LL-F28249 compounds
US4886828A (en) 1986-09-12 1989-12-12 American Cyanamid Company Δ22 -derivatives of LL-F28249 compounds
GB8813150D0 (en) 1988-06-03 1988-07-06 American Cyanamid Co Chemical compounds
ES2052173T3 (es) * 1989-04-11 1994-07-01 Pfizer Composiciones inyectables que contienen 25-cyclohexil-avermectina b1.
NZ234802A (en) 1989-08-14 1992-11-25 Merck & Co Inc Long acting injectable formulations comprising an avermectin compound and triacetin. treatment for internal and external parasites of animals
US5055486A (en) 1989-12-22 1991-10-08 American Cyanamid Company 13-alkyl-23-imino derivative of LL-F28249 compounds and their use as endo- and ectoparasiticidal, insecticidal, acaricidal and nematocidal agents
US5030650A (en) 1989-09-11 1991-07-09 American Cyanamid Company 13-halo-23-imino derivatives of LL-F28249 compounds and their use as endo- and ectoparasiticidal, insecticidal, acaricidal and nematocidal agents
DE69208765T2 (de) 1991-07-23 1996-09-26 American Cyanamid Co Stabile Zusammensetzungen für parenterale Verabrechung und ihre Verwendung
JPH08502404A (ja) 1992-10-21 1996-03-19 マリンクロット ベテリナリー，アイエヌシー， チオールプロテアーゼを含有するワクチン
JPH07505787A (ja) * 1993-02-05 1995-06-29 ダラテク・プロプライエタリー・リミテッド ファスキオラ種から取得可能なポリペプチド類，およびワクチン，処置法およびそのｄｎａ配列
GB9312324D0 (en) 1993-06-15 1993-07-28 Pitman Moore Inc Vaccine
AU7349596A (en) 1995-05-17 1996-12-11 International Centre of Insect Physiology and Ecology, The Novel method of enhancing efficiency of anti-arthropod agents against blood-feeding ectoparasites
ES2174027T3 (es) * 1995-06-30 2002-11-01 American Cyanamid Co Composiciones estables que contienen macrolidos y macrolidos combinados con unas vacunas.
CA2233016C (en) * 1995-09-25 2007-07-17 Ashmont Holdings Limited Anthelmintic macrocyclic lactone compositions
AU728221B2 (en) * 1996-06-05 2001-01-04 Ashmont Holdings Limited Injectable compositions
GB9612214D0 (en) 1996-06-11 1996-08-14 Mallinckrodt Veterinary Inc Vaccine
HRP20040195B1 (hr) * 2001-07-27 2014-07-18 Zoetis W Llc Cjepivo protiv bolesti zapadnoga nila
TWI350174B (en) * 2003-03-12 2011-10-11 Wyeth Corp Adjuvanted bovine vaccines
TW201010719A (en) * 2008-08-19 2010-03-16 Wyeth Corp Immunological composition

Also Published As

Publication number Publication date
UY32930A (es) 2011-05-31
WO2011043962A2 (en) 2011-04-14
EP2485725A2 (en) 2012-08-15
MX2012004133A (es) 2012-05-08
BR112012008185A2 (pt) 2016-08-16
AU2010303741A1 (en) 2012-04-19
TW201127398A (en) 2011-08-16
WO2011043962A3 (en) 2011-06-03
US20110091559A1 (en) 2011-04-21

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal