AR077577A2 - POLIPEPTIDES RELATED TO CANCER OF HUMAN COLON, POLYUCLEOTIDES THAT CODE IT, VECTOR, USES AND PHARMACEUTICAL COMPOSITIONS - Google Patents
POLIPEPTIDES RELATED TO CANCER OF HUMAN COLON, POLYUCLEOTIDES THAT CODE IT, VECTOR, USES AND PHARMACEUTICAL COMPOSITIONSInfo
- Publication number
- AR077577A2 AR077577A2 ARP100102600A AR077577A2 AR 077577 A2 AR077577 A2 AR 077577A2 AR P100102600 A ARP100102600 A AR P100102600A AR 077577 A2 AR077577 A2 AR 077577A2
- Authority
- AR
- Argentina
- Prior art keywords
- cancer
- vector
- polyucleotides
- polipeptides
- code
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 3
- 201000011510 cancer Diseases 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- 210000001072 colon Anatomy 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 206010009944 Colon cancer Diseases 0.000 abstract 1
- 208000001333 Colorectal Neoplasms Diseases 0.000 abstract 1
- 101000692702 Homo sapiens E3 ubiquitin-protein ligase RNF43 Proteins 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 102000052942 human RNF43 Human genes 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
Landscapes
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
En humano RNF43 cuya expresion está marcadamente elevada en el cáncer colorrectal en comparacion con los correspondientes tejidos no canceroso, se provee además un vector que comprende el polinucleotido, el uso del polipéptido para la manufactura de una composicion farmacéutica para tratar o prevenir el cáncer, y una composicion farmacéutica contra el cáncer. Los genes y los polipéptidos codificados por los genes se pueden usar, por ejemplo, en el diagnostico de una enfermedad de células proliferativas, y como moléculas blanco para desarrollar fármacos contra la enfermedad. Reivindicacion 1: Un polipéptido sustancialmente puro, caracterizado porque consiste de la secuencia de aminoácidos que se selecciona del grupo que consiste de las SEQ ID Ns 42, 59 y 70.In human RNF43 whose expression is markedly elevated in colorectal cancer compared to the corresponding non-cancerous tissues, a vector comprising the polynucleotide, the use of the polypeptide for the manufacture of a pharmaceutical composition to treat or prevent cancer, and a pharmaceutical composition against cancer. Genes and polypeptides encoded by genes can be used, for example, in the diagnosis of a proliferative cell disease, and as white molecules to develop drugs against the disease. Claim 1: A substantially pure polypeptide, characterized in that it consists of the amino acid sequence that is selected from the group consisting of SEQ ID Nos. 42, 59 and 70.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45101303P | 2003-02-28 | 2003-02-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR077577A2 true AR077577A2 (en) | 2011-09-07 |
Family
ID=42778403
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP030104390A AR045408A1 (en) | 2003-02-28 | 2003-11-27 | GENES AND POLYPEPTIDES RELATED TO CANCER OF HUMAN COLON |
| ARP100102600 AR077577A2 (en) | 2003-02-28 | 2010-07-15 | POLIPEPTIDES RELATED TO CANCER OF HUMAN COLON, POLYUCLEOTIDES THAT CODE IT, VECTOR, USES AND PHARMACEUTICAL COMPOSITIONS |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP030104390A AR045408A1 (en) | 2003-02-28 | 2003-11-27 | GENES AND POLYPEPTIDES RELATED TO CANCER OF HUMAN COLON |
Country Status (2)
| Country | Link |
|---|---|
| AR (2) | AR045408A1 (en) |
| TW (1) | TWI324608B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI596109B (en) * | 2007-02-21 | 2017-08-21 | 腫瘤療法 科學股份有限公司 | Peptide vaccine for cancers exhibiting tumor-associated antigens |
| TW201008574A (en) | 2008-08-19 | 2010-03-01 | Oncotherapy Science Inc | INHBB epitope peptides and vaccines containing the same |
| BRPI0923402A2 (en) | 2008-12-24 | 2015-08-04 | Oncotherapy Science Inc | C10rf59 peptides and vaccines including the same. |
-
2003
- 2003-11-24 TW TW092132870A patent/TWI324608B/en not_active IP Right Cessation
- 2003-11-27 AR ARP030104390A patent/AR045408A1/en active IP Right Grant
-
2010
- 2010-07-15 AR ARP100102600 patent/AR077577A2/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AR045408A1 (en) | 2005-10-26 |
| TW200502247A (en) | 2005-01-16 |
| TWI324608B (en) | 2010-05-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |