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AR076856A1 - LENALIDOMIDE POLYMORPH AND PROCESS FOR PREPARATION - Google Patents

LENALIDOMIDE POLYMORPH AND PROCESS FOR PREPARATION

Info

Publication number
AR076856A1
AR076856A1 ARP100101577A ARP100101577A AR076856A1 AR 076856 A1 AR076856 A1 AR 076856A1 AR P100101577 A ARP100101577 A AR P100101577A AR P100101577 A ARP100101577 A AR P100101577A AR 076856 A1 AR076856 A1 AR 076856A1
Authority
AR
Argentina
Prior art keywords
preparation
lenalidomide
polymorph
crystalline
theta
Prior art date
Application number
ARP100101577A
Other languages
Spanish (es)
Inventor
Srinivasulu Rangineni
Shakti Singh
Vamsi Krishna Muppidi
Original Assignee
Reddys Lab Ltd Dr
Reddys Lab Inc Dr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reddys Lab Ltd Dr, Reddys Lab Inc Dr filed Critical Reddys Lab Ltd Dr
Publication of AR076856A1 publication Critical patent/AR076856A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente solicitud se relaciona con una forma cristalina de la lenalidomida, procesos para su preparacion, y el uso de la forma polimorfica en la preparacion de composiciones farmacéuticas. Reivindicacion 1: Lenalidomida cristalina con un patron de difraccion de rayos-x en polvo que comprende uno o más picos localizados en las posiciones 8,29; 25,9 y 27,5 0,2 grados 2-theta.The present application relates to a crystalline form of lenalidomide, processes for its preparation, and the use of the polymorphic form in the preparation of pharmaceutical compositions. Claim 1: Crystalline Lenalidomide with a powder x-ray diffraction pattern comprising one or more peaks located at positions 8.29; 25.9 and 27.5 0.2 degrees 2-theta.

ARP100101577A 2009-05-08 2010-05-07 LENALIDOMIDE POLYMORPH AND PROCESS FOR PREPARATION AR076856A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1079CH2009 2009-05-08
US22652409P 2009-07-17 2009-07-17

Publications (1)

Publication Number Publication Date
AR076856A1 true AR076856A1 (en) 2011-07-13

Family

ID=43050836

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP100101577A AR076856A1 (en) 2009-05-08 2010-05-07 LENALIDOMIDE POLYMORPH AND PROCESS FOR PREPARATION

Country Status (2)

Country Link
AR (1) AR076856A1 (en)
WO (1) WO2010129636A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA83504C2 (en) 2003-09-04 2008-07-25 Селджин Корпорейшн Polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione
TWI475014B (en) * 2009-09-17 2015-03-01 Scinopharm Taiwan Ltd Solid forms of 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2, 6-dione and methods of making the same
WO2011061611A1 (en) * 2009-11-19 2011-05-26 Ranbaxy Laboratories Limited Process for the preparation of form b of lenalidomide
WO2012127493A1 (en) 2011-03-23 2012-09-27 Hetero Research Foundation Polymorphs of lenalidomide
WO2016024286A2 (en) * 2014-08-11 2016-02-18 Avra Laboratories Pvt. Ltd. An improved process for synthesis of lenalidomide
EP3135275B1 (en) * 2015-08-27 2020-05-13 Grindeks, A Joint Stock Company Pharmaceutical composition capable of the incorporation of lenalidomide in various crystalline modifications
TWI664172B (en) * 2016-08-25 2019-07-01 大陸商浙江海正藥業股份有限公司 Crystal form of lenalidomide, preparation method and application thereof
CN112999224B (en) * 2021-03-03 2022-09-16 天津大学 Ibuprofen-loaded lenalidomide composite particle and preparation method thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5635517B1 (en) * 1996-07-24 1999-06-29 Celgene Corp Method of reducing TNFalpha levels with amino substituted 2-(2,6-dioxopiperidin-3-YL)-1-oxo-and 1,3-dioxoisoindolines
UA83504C2 (en) * 2003-09-04 2008-07-25 Селджин Корпорейшн Polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione

Also Published As

Publication number Publication date
WO2010129636A2 (en) 2010-11-11
WO2010129636A3 (en) 2011-03-31

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