AR062950A1 - Compuestos tetraciclicos, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen - Google Patents
Compuestos tetraciclicos, su procedimiento de preparacion y las composiciones farmaceuticas que los contienenInfo
- Publication number
- AR062950A1 AR062950A1 ARP070104197A ARP070104197A AR062950A1 AR 062950 A1 AR062950 A1 AR 062950A1 AR P070104197 A ARP070104197 A AR P070104197A AR P070104197 A ARP070104197 A AR P070104197A AR 062950 A1 AR062950 A1 AR 062950A1
- Authority
- AR
- Argentina
- Prior art keywords
- compounds
- tetraciclic
- pharmaceutical compositions
- compositions containing
- preparation procedure
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000036506 anxiety Effects 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000003291 dopaminomimetic effect Effects 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000002483 medication Methods 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Gynecology & Obstetrics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Compuestos de la formula 1, de configuracion relativa trans: en la que: X representa un átomo de oxigeno o un grupo NR2, Y representa un grupo elegido entre -CH2-, -(CH2)2- y -CH=CH-, R1 y R2, idénticos o diferentes, representando cada uno un átomo de hidrogeno o un grupo elegido entre alquilo, cicloalquilo y cicloalquilalquilo, bajo forma racémica o de isomeros opticos, así como sus sales de adicion con un ácido farmacéuticamente aceptable y sus hidratos. Composicion farmacéutica. Proceso. Medicamentos utiles para tratar enfermedades del sistema nervioso central en las que está implicado el sistema dopaminérgico como depresion, ansiedad, Alzheimer, Parkinson.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0608413A FR2906249B1 (fr) | 2006-09-26 | 2006-09-26 | Composes tetracycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR062950A1 true AR062950A1 (es) | 2008-12-17 |
Family
ID=37877016
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP070104197A AR062950A1 (es) | 2006-09-26 | 2007-09-24 | Compuestos tetraciclicos, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US7470683B2 (es) |
| EP (1) | EP1905775B1 (es) |
| JP (1) | JP2008100995A (es) |
| KR (1) | KR100934315B1 (es) |
| CN (1) | CN101153043B (es) |
| AR (1) | AR062950A1 (es) |
| AT (1) | ATE480544T1 (es) |
| AU (1) | AU2007219281A1 (es) |
| BR (1) | BRPI0703655A2 (es) |
| CA (1) | CA2603274C (es) |
| CY (1) | CY1110799T1 (es) |
| DE (1) | DE602007009004D1 (es) |
| DK (1) | DK1905775T3 (es) |
| EA (1) | EA013406B1 (es) |
| ES (1) | ES2351945T3 (es) |
| FR (1) | FR2906249B1 (es) |
| GE (1) | GEP20104877B (es) |
| HR (1) | HRP20100605T1 (es) |
| MA (1) | MA29371B1 (es) |
| MX (1) | MX2007011524A (es) |
| MY (1) | MY142517A (es) |
| NO (1) | NO20074889L (es) |
| NZ (1) | NZ561905A (es) |
| PL (1) | PL1905775T3 (es) |
| PT (1) | PT1905775E (es) |
| RS (1) | RS51418B (es) |
| SG (1) | SG141382A1 (es) |
| SI (1) | SI1905775T1 (es) |
| UA (1) | UA96125C2 (es) |
| WO (1) | WO2008037888A2 (es) |
| ZA (1) | ZA200708215B (es) |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1204745A (en) * | 1981-11-20 | 1986-05-20 | Merck Co. | Hexahydronaphth (1,2-b) -1,4 -oxazines |
| US4420480A (en) * | 1981-11-20 | 1983-12-13 | Merck & Co., Inc. | Hexahydronaphth[1,2-b]-1,4-oxazines |
| FR2721027B1 (fr) * | 1994-06-08 | 1996-07-19 | Adir | Nouveaux dérivés tétracycliques de la 1,4-oxazine, leur procédé de préparation et les compositions pharmaceutiques les contenant. |
| FR2741074B1 (fr) | 1995-11-09 | 1997-12-19 | Adir | Nouveaux composes tetracycliques de la 1,4-oxazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2767825A1 (fr) | 1997-09-01 | 1999-02-26 | Adir | Nouvelles trans-3,4,4a,5,6,10b-hexahydro-2h-napht°1,2-b!-1, 4-oxazines disubstituees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2845994B1 (fr) * | 2002-10-18 | 2006-05-19 | Servier Lab | Nouveaux derives de benzo[e][1,4]oxazino[3,2-g]isoindole substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
-
2006
- 2006-09-26 FR FR0608413A patent/FR2906249B1/fr not_active Expired - Fee Related
-
2007
- 2007-09-11 MA MA30219A patent/MA29371B1/fr unknown
- 2007-09-19 MX MX2007011524A patent/MX2007011524A/es unknown
- 2007-09-21 KR KR1020070096525A patent/KR100934315B1/ko not_active Expired - Fee Related
- 2007-09-24 EA EA200701807A patent/EA013406B1/ru not_active IP Right Cessation
- 2007-09-24 SG SG200708582-2A patent/SG141382A1/en unknown
- 2007-09-24 CN CN2007101617348A patent/CN101153043B/zh not_active Expired - Fee Related
- 2007-09-24 AR ARP070104197A patent/AR062950A1/es unknown
- 2007-09-24 AU AU2007219281A patent/AU2007219281A1/en not_active Abandoned
- 2007-09-25 US US11/904,006 patent/US7470683B2/en not_active Expired - Fee Related
- 2007-09-25 ES ES07291135T patent/ES2351945T3/es active Active
- 2007-09-25 NZ NZ561905A patent/NZ561905A/en not_active IP Right Cessation
- 2007-09-25 RS RSP-2010/0420A patent/RS51418B/sr unknown
- 2007-09-25 PL PL07291135T patent/PL1905775T3/pl unknown
- 2007-09-25 GE GEAP200710284A patent/GEP20104877B/en unknown
- 2007-09-25 AT AT07291135T patent/ATE480544T1/de active
- 2007-09-25 WO PCT/FR2007/001557 patent/WO2008037888A2/fr not_active Ceased
- 2007-09-25 PT PT07291135T patent/PT1905775E/pt unknown
- 2007-09-25 MY MYPI20071605A patent/MY142517A/en unknown
- 2007-09-25 SI SI200730350T patent/SI1905775T1/sl unknown
- 2007-09-25 EP EP07291135A patent/EP1905775B1/fr active Active
- 2007-09-25 DE DE602007009004T patent/DE602007009004D1/de active Active
- 2007-09-25 DK DK07291135.7T patent/DK1905775T3/da active
- 2007-09-26 JP JP2007248428A patent/JP2008100995A/ja not_active Ceased
- 2007-09-26 CA CA2603274A patent/CA2603274C/fr not_active Expired - Fee Related
- 2007-09-26 NO NO20074889A patent/NO20074889L/no not_active Application Discontinuation
- 2007-09-26 BR BRPI0703655-8A patent/BRPI0703655A2/pt not_active IP Right Cessation
- 2007-09-26 ZA ZA200708215A patent/ZA200708215B/xx unknown
- 2007-09-26 UA UAA200710656A patent/UA96125C2/ru unknown
-
2010
- 2010-09-24 CY CY20101100862T patent/CY1110799T1/el unknown
- 2010-11-10 HR HR20100605T patent/HRP20100605T1/hr unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |