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AR061728A1 - COMPOSITION FOR TREATMENT USING SELECTIVE COMPOUNDS ALFA-2-DELTA-1 - Google Patents

COMPOSITION FOR TREATMENT USING SELECTIVE COMPOUNDS ALFA-2-DELTA-1

Info

Publication number
AR061728A1
AR061728A1 ARP070102894A ARP070102894A AR061728A1 AR 061728 A1 AR061728 A1 AR 061728A1 AR P070102894 A ARP070102894 A AR P070102894A AR P070102894 A ARP070102894 A AR P070102894A AR 061728 A1 AR061728 A1 AR 061728A1
Authority
AR
Argentina
Prior art keywords
delta
composition
alpha
ligand
alfa
Prior art date
Application number
ARP070102894A
Other languages
Spanish (es)
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of AR061728A1 publication Critical patent/AR061728A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • A61P25/10Antiepileptics; Anticonvulsants for petit-mal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Reproductive Health (AREA)
  • Psychology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Anesthesiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Una composicion para tratar un trastorno o afeccion usando un ligando alfa-2-delta, como por ejemplo, ácido (3S,4R,5R)-3-amino-4,5-dimetil octanoico, con gran afinidad y selectividad para el subtipo de la subunidad alfa-2-delta-1del canal de calcio. La administracion del ligando selectivo alfa-2-delta-1, o una sal farmacéuticamente aceptable, a un mamífero, incluyendo un hombre, evita o reduce los efectos adversos en comparacion con la administracion de un ligando no selectivo alfa-2-delta. Reivindicacion 7: La composicion de acuerdo con la reivindicacion 1 caracterizada porque el trastorno o afeccion es seleccionado de dolor, fibromialgia, epilepsia, síndrome de piernas inquietas, sofocos, trastornos del humor y trastornos del sueno.A composition for treating a disorder or condition using an alpha-2-delta ligand, such as, for example, (3S, 4R, 5R) -3-amino-4,5-dimethyl octanoic acid, with high affinity and selectivity for the subtype of the alpha-2-delta-1 subunit of the calcium channel. The administration of the selective alpha-2-delta-1 ligand, or a pharmaceutically acceptable salt, to a mammal, including a man, avoids or reduces adverse effects compared to the administration of a non-selective alpha-2-delta ligand. Claim 7: The composition according to claim 1 characterized in that the disorder or condition is selected from pain, fibromyalgia, epilepsy, restless legs syndrome, hot flashes, mood disorders and sleep disorders.

ARP070102894A 2006-06-30 2007-06-28 COMPOSITION FOR TREATMENT USING SELECTIVE COMPOUNDS ALFA-2-DELTA-1 AR061728A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81815406P 2006-06-30 2006-06-30

Publications (1)

Publication Number Publication Date
AR061728A1 true AR061728A1 (en) 2008-09-17

Family

ID=38739992

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP070102894A AR061728A1 (en) 2006-06-30 2007-06-28 COMPOSITION FOR TREATMENT USING SELECTIVE COMPOUNDS ALFA-2-DELTA-1

Country Status (4)

Country Link
JP (1) JP2008013555A (en)
AR (1) AR061728A1 (en)
TW (1) TW200819123A (en)
WO (1) WO2008004067A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY160403A (en) 2007-11-05 2017-03-15 Unilever Plc Process for manufacturing tea products
AU2018274569B2 (en) * 2017-05-26 2022-06-30 Novassay Sa Voltage-Gated Calcium Channel auxilliary subunit alpha 2 delta and uses thereof
WO2021079887A1 (en) * 2019-10-25 2021-04-29 国立大学法人京都大学 Preventative or therapeutic agent for tauopathy

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2260850T3 (en) * 1997-10-27 2006-11-01 Warner-Lambert Company Llc CYCLINE AMINOACIDS AND ITS DERIVATIVES USED AS PHARMACEUTICAL AGENTS.
AU765802B2 (en) * 1997-12-16 2003-10-02 Warner-Lambert Company 1-substituted-1-aminomethyl-cycloalkane derivatives (=gabapentin analogues), their preparation and their use in the treatment of neurological disorders
EA004398B1 (en) * 1999-06-10 2004-04-29 Уорнер-Ламберт Компани Mono- and disubstituted 3-propyl gamma-aminobutyric acids
HN2000000224A (en) * 1999-10-20 2001-04-11 Warner Lambert Co BICYCLE AMINO ACIDS AS PHARMACEUTICAL AGENTS
WO2002085839A1 (en) * 2001-04-19 2002-10-31 Warner-Lambert Company Llc Fused bicyclic or tricyclic amino acids
NI200300043A (en) * 2002-03-28 2003-11-05 Warner Lambert Co AMINO ACIDS WITH AFFINITY FOR THE PROTEIN a2DELTA.
GB0225379D0 (en) * 2002-10-31 2002-12-11 Pfizer Ltd Therapeutic proline derivatives
EP1667957A2 (en) * 2003-09-25 2006-06-14 Warner-Lambert Company LLC Amino acids with affinity for the alpha2delta-protein
WO2005102390A2 (en) * 2004-04-22 2005-11-03 Pfizer Japan, Inc. Combinations comprising alpha-2-delta ligands and nmda receptor antagonists
EP1774318A2 (en) * 2004-07-13 2007-04-18 The Regents of The University of California Models and methods for nociception, pain transduction, and screening for analgesic compounds
WO2006100606A2 (en) * 2005-03-24 2006-09-28 Warner-Lambert Company Llc Preparation of beta-amino acid precursors via indium (iii) mediated markovnikov addition and knoevenagel condensation

Also Published As

Publication number Publication date
TW200819123A (en) 2008-05-01
JP2008013555A (en) 2008-01-24
WO2008004067A3 (en) 2009-01-29
WO2008004067A2 (en) 2008-01-10

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal