AR061400A1 - Agentes para suprimir el dano a los islotes transplantados despues del transplante de islotes - Google Patents
Agentes para suprimir el dano a los islotes transplantados despues del transplante de islotesInfo
- Publication number
- AR061400A1 AR061400A1 ARP060104507A ARP060104507A AR061400A1 AR 061400 A1 AR061400 A1 AR 061400A1 AR P060104507 A ARP060104507 A AR P060104507A AR P060104507 A ARP060104507 A AR P060104507A AR 061400 A1 AR061400 A1 AR 061400A1
- Authority
- AR
- Argentina
- Prior art keywords
- transplanted
- inhibitor
- transplant
- agents
- islots
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Obesity (AREA)
- Rheumatology (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Surgery (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Emergency Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Reivindicacion 1: Un agente para suprimir el dano a los islotes transplantados después del transplante de islotes, caracterizado porque comprende un inhibidor de IL-6 como ingrediente activo. Reivindicacion 2: El agente para suprimir el dano a los islotes transplantados de la reivindicacion 1, caracterizado porque el inhibidor de IL-6 es un anticuerpo que reconoce una IL-6. Reivindicacion 9: Un método para suprimir el dano a los islotes transplantados en un sujeto sometido a un transplante de islotes, caracterizado porque comprende el paso de administrarle un inhibidor de IL-6 al sujeto. Reivindicacion 10: Un método para mejorar la viabilidad de un transplante de islotes en un sujeto, caracterizado porque comprende el paso de administrarle un inhibidor de IL-6 al sujeto. Reivindicacion 17: El uso de un inhibidor de IL-6, caracterizado porque es para producir agentes para suprimir el dano a los islotes transplantados después del transplante de islotes.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005300489 | 2005-10-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR061400A1 true AR061400A1 (es) | 2008-08-27 |
Family
ID=37942862
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP060104507A AR061400A1 (es) | 2005-10-14 | 2006-10-13 | Agentes para suprimir el dano a los islotes transplantados despues del transplante de islotes |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8470316B2 (es) |
| EP (1) | EP1941907B1 (es) |
| JP (1) | JP5014143B2 (es) |
| KR (1) | KR101343190B1 (es) |
| CN (1) | CN101330929B (es) |
| AR (1) | AR061400A1 (es) |
| AU (1) | AU2006300234B2 (es) |
| BR (1) | BRPI0617378B8 (es) |
| CA (1) | CA2625773C (es) |
| IL (1) | IL190693A (es) |
| NO (1) | NO20082194L (es) |
| RU (1) | RU2446826C2 (es) |
| WO (1) | WO2007043641A1 (es) |
| ZA (1) | ZA200803973B (es) |
Families Citing this family (50)
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|---|---|---|---|---|
| AU736282B2 (en) | 1997-03-21 | 2001-07-26 | Chugai Seiyaku Kabushiki Kaisha | A preventive or therapeutic agent for sensitized T cell- mediated diseases comprising IL-6 antagonist as an active ingredient |
| UA80091C2 (en) | 2001-04-02 | 2007-08-27 | Chugai Pharmaceutical Co Ltd | Remedies for infant chronic arthritis-relating diseases and still's disease which contain an interleukin-6 (il-6) antagonist |
| AU2003211991B2 (en) * | 2002-02-14 | 2008-08-21 | Chugai Seiyaku Kabushiki Kaisha | Antibody-containing solution formulations |
| GB2401040A (en) | 2003-04-28 | 2004-11-03 | Chugai Pharmaceutical Co Ltd | Method for treating interleukin-6 related diseases |
| US8398980B2 (en) * | 2004-03-24 | 2013-03-19 | Chugai Seiyaku Kabushiki Kaisha | Subtypes of humanized antibody against interleuken-6 receptor |
| CN101198698B (zh) | 2005-03-31 | 2014-03-19 | 中外制药株式会社 | 通过调节多肽缔合制备多肽的方法 |
| WO2007043641A1 (ja) | 2005-10-14 | 2007-04-19 | Fukuoka University | 膵島移植における移植膵島障害抑制剤 |
| RU2450830C2 (ru) | 2005-10-21 | 2012-05-20 | Чугаи Сейяку Кабусики Кайся | Средства для лечения кардиопатии |
| AR057582A1 (es) * | 2005-11-15 | 2007-12-05 | Nat Hospital Organization | Agentes para suprimir la induccion de linfocitos t citotoxicos |
| KR20080084818A (ko) * | 2005-11-25 | 2008-09-19 | 각고호우징 게이오기주크 | 전립선암 치료제 |
| EP3135298B1 (en) * | 2006-01-27 | 2018-06-06 | Keio University | Therapeutic agents for diseases involving choroidal neovascularization |
| DK2009101T3 (en) | 2006-03-31 | 2018-01-15 | Chugai Pharmaceutical Co Ltd | Antibody modification method for purification of a bispecific antibody |
| IN2014DN10515A (es) | 2006-03-31 | 2015-08-21 | Chugai Pharmaceutical Co Ltd | |
| CA2648644C (en) * | 2006-04-07 | 2016-01-05 | Osaka University | Muscle regeneration promoter |
| AU2008208321B2 (en) * | 2007-01-23 | 2013-03-21 | Chugai Seiyaku Kabushiki Kaisha | Chronic rejection inhibitor |
| WO2008135419A2 (en) * | 2007-05-04 | 2008-11-13 | Charité Universitätsmedizin Berlin | Anti-il-6-agents for improving primary functioning of allogenic grafts |
| JP5334319B2 (ja) | 2007-09-26 | 2013-11-06 | 中外製薬株式会社 | Cdrのアミノ酸置換により抗体の等電点を改変する方法 |
| KR101922788B1 (ko) | 2007-09-26 | 2018-11-27 | 추가이 세이야쿠 가부시키가이샤 | 항체 정상영역 개변체 |
| EP2236604B1 (en) | 2007-12-05 | 2016-07-06 | Chugai Seiyaku Kabushiki Kaisha | Anti-nr10 antibody and use thereof |
| PE20091174A1 (es) | 2007-12-27 | 2009-08-03 | Chugai Pharmaceutical Co Ltd | Formulacion liquida con contenido de alta concentracion de anticuerpo |
| WO2009125825A1 (ja) | 2008-04-11 | 2009-10-15 | 中外製薬株式会社 | 複数分子の抗原に繰り返し結合する抗原結合分子 |
| CN102256623A (zh) * | 2008-06-05 | 2011-11-23 | 独立行政法人国立癌症研究中心 | 神经浸润抑制剂 |
| TWI440469B (zh) | 2008-09-26 | 2014-06-11 | Chugai Pharmaceutical Co Ltd | Improved antibody molecules |
| US20120071634A1 (en) | 2009-03-19 | 2012-03-22 | Chugai Seiyaku Kabushiki Kaisha | Antibody Constant Region Variant |
| WO2010107110A1 (ja) | 2009-03-19 | 2010-09-23 | 中外製薬株式会社 | 抗体定常領域改変体 |
| EP2431393B1 (en) | 2009-05-15 | 2018-05-02 | Chugai Seiyaku Kabushiki Kaisha | Anti-axl antibody |
| EP2481752B1 (en) | 2009-09-24 | 2016-11-09 | Chugai Seiyaku Kabushiki Kaisha | Modified antibody constant regions |
| US20110117087A1 (en) | 2009-10-26 | 2011-05-19 | Reinhard Franze | Method for the production of a glycosylated immunoglobulin |
| EP2543730B1 (en) | 2010-03-04 | 2018-10-31 | Chugai Seiyaku Kabushiki Kaisha | Antibody constant region variant |
| RS63800B1 (sr) | 2010-05-28 | 2022-12-30 | Chugai Pharmaceutical Co Ltd | Poboljšanje antitumorskog odgovora t ćelije |
| CN104998254A (zh) | 2010-11-08 | 2015-10-28 | 基因技术公司 | 皮下施用的抗-il-6受体抗体 |
| EP4231014A3 (en) | 2010-11-30 | 2024-08-14 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule capable of binding to plurality of antigen molecules repeatedly |
| JP2014161257A (ja) * | 2013-02-22 | 2014-09-08 | Univ Of Tokyo | 多能性幹細胞から膵ランゲルハンス島を製造する方法 |
| JP6442404B2 (ja) | 2013-06-11 | 2018-12-19 | 国立研究開発法人国立精神・神経医療研究センター | 再発寛解型多発性硬化症(rrms)患者の治療予後予測方法、及び新規治療適応判断方法 |
| WO2015000865A1 (en) | 2013-07-04 | 2015-01-08 | F. Hoffmann-La Roche Ag | Interference-suppressed immunoassay to detect anti-drug antibodies in serum samples |
| US9550828B2 (en) | 2013-09-05 | 2017-01-24 | Boise State University | Oncostatin M (OSM) antagonists for preventing cancer metastasis and IL-6 related disorders |
| RU2730594C2 (ru) | 2013-09-27 | 2020-08-24 | Чугаи Сейяку Кабусики Кайся | Способ получения полипептидного гетеромультимера |
| US10774148B2 (en) | 2015-02-27 | 2020-09-15 | Chugai Seiyaku Kabushiki Kaisha | Composition for treating IL-6-related diseases |
| EP3279216A4 (en) | 2015-04-01 | 2019-06-19 | Chugai Seiyaku Kabushiki Kaisha | PROCESS FOR PREPARING POLYPEPTIDE HETERO OLIGOMER |
| US10697883B2 (en) | 2015-05-19 | 2020-06-30 | National Center Of Neurology And Psychiatry | Method for determining application of therapy to multiple sclerosis (MS) patient |
| CN108368166B (zh) | 2015-12-28 | 2023-03-28 | 中外制药株式会社 | 提高含fc区多肽纯化效率的方法 |
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| SG10201607778XA (en) | 2016-09-16 | 2018-04-27 | Chugai Pharmaceutical Co Ltd | Anti-Dengue Virus Antibodies, Polypeptides Containing Variant Fc Regions, And Methods Of Use |
| EP3596175A4 (en) | 2017-03-17 | 2021-01-13 | The Ohio State Innovation Foundation | NANOPARTICLES FOR THE ADMINISTRATION OF CHEMOPREVENTIVE AGENTS |
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| JP7185884B2 (ja) | 2017-05-02 | 2022-12-08 | 国立研究開発法人国立精神・神経医療研究センター | Il-6及び好中球の関連する疾患の治療効果の予測及び判定方法 |
| WO2019078344A1 (ja) | 2017-10-20 | 2019-04-25 | 学校法人兵庫医科大学 | 抗il-6受容体抗体を含有する術後の癒着を抑制するための医薬組成物 |
| CN112119090B (zh) | 2018-03-15 | 2023-01-13 | 中外制药株式会社 | 对寨卡病毒具有交叉反应性的抗登革热病毒抗体及使用方法 |
| JP2022527972A (ja) | 2019-04-02 | 2022-06-07 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | 前悪性病変を有する患者において癌を予測及び予防する方法 |
| US11633457B2 (en) | 2019-04-11 | 2023-04-25 | Boise State University | Pharmaceutical compositions comprising oncostatin m (OSM) antagonist derivatives and methods of use |
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-
2006
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- 2006-10-13 CA CA2625773A patent/CA2625773C/en active Active
- 2006-10-13 CN CN200680047109.4A patent/CN101330929B/zh active Active
- 2006-10-13 EP EP06811729.0A patent/EP1941907B1/en active Active
- 2006-10-13 BR BRPI0617378A patent/BRPI0617378B8/pt active IP Right Grant
- 2006-10-13 US US12/090,061 patent/US8470316B2/en active Active
- 2006-10-13 RU RU2008118906/15A patent/RU2446826C2/ru not_active IP Right Cessation
- 2006-10-13 AR ARP060104507A patent/AR061400A1/es unknown
- 2006-10-13 AU AU2006300234A patent/AU2006300234B2/en active Active
- 2006-10-13 JP JP2007539996A patent/JP5014143B2/ja active Active
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- 2008-05-09 ZA ZA200803973A patent/ZA200803973B/xx unknown
- 2008-05-13 NO NO20082194A patent/NO20082194L/no unknown
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Also Published As
| Publication number | Publication date |
|---|---|
| CN101330929A (zh) | 2008-12-24 |
| ZA200803973B (en) | 2009-03-25 |
| JPWO2007043641A1 (ja) | 2009-04-16 |
| EP1941907A1 (en) | 2008-07-09 |
| EP1941907B1 (en) | 2016-03-23 |
| KR20080064154A (ko) | 2008-07-08 |
| HK1124533A1 (en) | 2009-07-17 |
| BRPI0617378B1 (pt) | 2021-08-10 |
| RU2446826C2 (ru) | 2012-04-10 |
| CA2625773C (en) | 2015-05-12 |
| IL190693A (en) | 2014-12-31 |
| NO20082194L (no) | 2008-07-11 |
| BRPI0617378A2 (pt) | 2011-07-26 |
| BRPI0617378B8 (pt) | 2022-09-20 |
| RU2008118906A (ru) | 2009-11-20 |
| JP5014143B2 (ja) | 2012-08-29 |
| EP1941907A4 (en) | 2010-01-20 |
| AU2006300234A1 (en) | 2007-04-19 |
| US8470316B2 (en) | 2013-06-25 |
| CA2625773A1 (en) | 2007-04-19 |
| US20090220499A1 (en) | 2009-09-03 |
| KR101343190B1 (ko) | 2013-12-19 |
| CN101330929B (zh) | 2014-03-05 |
| WO2007043641A1 (ja) | 2007-04-19 |
| IL190693A0 (en) | 2008-11-03 |
| AU2006300234B2 (en) | 2013-01-10 |
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