AR069600A2 - Composiciones que comprenden un polipeptido aislado, o un anticuerpo aislado o fragmento que se une al antigeno del mismo, y un vehiculo, los vectores de expresion, las celulas hospedantes, los reactivos de diagnostico, los metodos para detectar chlamydia, anticuerpos anti-chlamydia y acidos nucleic - Google Patents
Composiciones que comprenden un polipeptido aislado, o un anticuerpo aislado o fragmento que se une al antigeno del mismo, y un vehiculo, los vectores de expresion, las celulas hospedantes, los reactivos de diagnostico, los metodos para detectar chlamydia, anticuerpos anti-chlamydia y acidos nucleicInfo
- Publication number
- AR069600A2 AR069600A2 ARP080105319A ARP080105319A AR069600A2 AR 069600 A2 AR069600 A2 AR 069600A2 AR P080105319 A ARP080105319 A AR P080105319A AR P080105319 A ARP080105319 A AR P080105319A AR 069600 A2 AR069600 A2 AR 069600A2
- Authority
- AR
- Argentina
- Prior art keywords
- seq
- polypeptide
- amino acids
- acid sequence
- amino acid
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 11
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 11
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 11
- 239000000203 mixture Substances 0.000 title abstract 6
- 150000007523 nucleic acids Chemical class 0.000 title abstract 4
- 239000012634 fragment Substances 0.000 title abstract 3
- 108020004707 nucleic acids Proteins 0.000 title abstract 3
- 102000039446 nucleic acids Human genes 0.000 title abstract 3
- 239000000427 antigen Substances 0.000 title abstract 2
- 102000036639 antigens Human genes 0.000 title abstract 2
- 108091007433 antigens Proteins 0.000 title abstract 2
- 239000013604 expression vector Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 9
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 7
- 241000606161 Chlamydia Species 0.000 abstract 4
- ZHNUHDYFZUAESO-UHFFFAOYSA-N Formamide Chemical compound NC=O ZHNUHDYFZUAESO-UHFFFAOYSA-N 0.000 abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 239000013612 plasmid Substances 0.000 abstract 2
- 231100000699 Bacterial toxin Toxicity 0.000 abstract 1
- 238000009007 Diagnostic Kit Methods 0.000 abstract 1
- 241000588724 Escherichia coli Species 0.000 abstract 1
- 241000672609 Escherichia coli BL21 Species 0.000 abstract 1
- 229930003779 Vitamin B12 Natural products 0.000 abstract 1
- 239000000688 bacterial toxin Substances 0.000 abstract 1
- 150000001720 carbohydrates Chemical class 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- FDJOLVPMNUYSCM-WZHZPDAFSA-L cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+3].N#[C-].N([C@@H]([C@]1(C)[N-]\C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C(\C)/C1=N/C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C\C1=N\C([C@H](C1(C)C)CCC(N)=O)=C/1C)[C@@H]2CC(N)=O)=C\1[C@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]1[C@@H](O)[C@@H](N2C3=CC(C)=C(C)C=C3N=C2)O[C@@H]1CO FDJOLVPMNUYSCM-WZHZPDAFSA-L 0.000 abstract 1
- 230000000295 complement effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
- 239000011715 vitamin B12 Substances 0.000 abstract 1
- 235000019163 vitamin B12 Nutrition 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
- G01N33/56927—Chlamydia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/295—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Chlamydiales (O)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
- C07K16/125—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Chlamydiales (O)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/295—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Chlamydiales (o)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
- Y10S530/811—Peptides or proteins is immobilized on, or in, an inorganic carrier
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
- Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
- Y10S530/813—Carrier is a saccharide
- Y10S530/814—Cellulose or derivatives thereof
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Una composicion que comprende un polipéptido aislado y un vehiculo, caracterizada porque dicho polipéptido comprende una secuencia de aminoácidos seleccionada del grupo que consiste de: (a) una secuencia de aminoácidos codificada por una secuencia de ácido nucleico la cual hibridiza en la presencia de 50% de formamida a 37°C-42°C, a una secuencia de DNA que es complementaria de la SEQ ID N°: 1, donde dicho polipéptido se puede reconocer por medio de una preparacion de anticuerpos que se une específicamente a un polipéptido que tiene la secuencia de aminoácidos SEQ ID N°: 2; (b) los aminoácidos 29-1013 de la SEQ ID N°: 15;: (c) los aminoácidos de la SEQ ID N°: 15; (d) los aminoácidos 29-1013 de la SEQ ID N°: 16; (e) los aminoácidos de la SEQ ID N°; 16; (f) los aminoácidos 29-1012 de la SEQ ID N°: 2; (g) los aminoácidos de la SEQ ID N°: 2; (h) los aminoácidos 29-553 de la SEQ ID N°: 2; (i) los aminoácidos 29-534 de la SEQ ID N°: 15; (j)) los aminoácidos 29-534 de la SEQ ID N°: 16; (k) una secuencia de aminoácidos codificada por el inserto de Chlamydia en el plásmido pAH342 de E. coli BL21, donde dicho polipéptido se puede reconocer mediante una preparacion de anticuerpos que se unen específicamente a un polipéptido que consiste de la secuencia de aminoácidos SEQ ID N°: 2; y (l) una secuencia de aminoácidos codificada por el inserto de Chlamydia en el plásmido pJJ701 de E. coli AR58, donde dicho polipéptido se puede reconocer mediante una preparacion de anticuerpos que se unen específicamente a un polipéptido que consiste de la secuencia de aminoácidos SEQ ID N°: 2. También se describen las composiciones que comprenden un anticuerpo aislado, o fragmento que se une al antígeno del mismo, y un vehiculo, los vectores de expresion, las células hospedantes, los reactivos de diagnostico, los métodos para detectar Chlamydia, ácidos nucleicos de Chlamydia y anticuerpos anti-Chlamydia, los kit de diagnostico y el uso de dichas composiciones que comprenden un polipéptido aislado y un vehículo, el vector, o la célula hospedante, para la preparacion de medicamentos. Reivindicacion 19: La composicion segun cualquiera de las reivindicaciones 1-18, caracterizada porque además comprende una molécula de enfoque combinada con o conjugada con dicho polipéptido. Reivindicacion 20: La composicion segun la reivindicacion 19, caracterizada porque la molécula de enfoque es vitamina B12, una toxina bacterial o un fragmento de la misma, un anticuerpo monoclonal, una proteína, un ácido nucleico, un carbohidrato, o una combinacion de dos o más de dichas moléculas de enfoque.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/942,596 US7459524B1 (en) | 1997-10-02 | 1997-10-02 | Chlamydia protein, sequence and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR069600A2 true AR069600A2 (es) | 2010-02-03 |
Family
ID=25478327
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP980104960A AR018013A1 (es) | 1997-10-02 | 1998-10-05 | Una proteina de alto peso molecular (hmw) aislada de especies de chlamydia y los acidos nucleicos, vectores de expresion recombinante, celulas huespedtransformadas, proteinas recombinantes, composiciones inmunogenicas y antigenicas, metodos para producir una respuesta inmune en animales, antisueros, |
| ARP080105319A AR069600A2 (es) | 1997-10-02 | 2008-12-05 | Composiciones que comprenden un polipeptido aislado, o un anticuerpo aislado o fragmento que se une al antigeno del mismo, y un vehiculo, los vectores de expresion, las celulas hospedantes, los reactivos de diagnostico, los metodos para detectar chlamydia, anticuerpos anti-chlamydia y acidos nucleic |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP980104960A AR018013A1 (es) | 1997-10-02 | 1998-10-05 | Una proteina de alto peso molecular (hmw) aislada de especies de chlamydia y los acidos nucleicos, vectores de expresion recombinante, celulas huespedtransformadas, proteinas recombinantes, composiciones inmunogenicas y antigenicas, metodos para producir una respuesta inmune en animales, antisueros, |
Country Status (15)
| Country | Link |
|---|---|
| US (6) | US7459524B1 (es) |
| EP (2) | EP1019028A4 (es) |
| JP (1) | JP2001518489A (es) |
| KR (1) | KR100586569B1 (es) |
| CN (2) | CN1911960B (es) |
| AR (2) | AR018013A1 (es) |
| AU (1) | AU752426B2 (es) |
| BR (1) | BR9813841A (es) |
| CA (1) | CA2305709A1 (es) |
| CO (1) | CO5050400A1 (es) |
| HU (1) | HUP0004639A3 (es) |
| NZ (1) | NZ503763A (es) |
| SA (1) | SA99191283B1 (es) |
| WO (1) | WO1999017741A1 (es) |
| ZA (1) | ZA989012B (es) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6710033B1 (en) | 1996-08-14 | 2004-03-23 | Vanderbilt University | Methods and treatment of multiple sclerosis |
| US5868735A (en) | 1997-03-06 | 1999-02-09 | Scimed Life Systems, Inc. | Cryoplasty device and method |
| US6890526B2 (en) | 1997-05-06 | 2005-05-10 | Vanderbilt University | Methods and reagents for the treatment of multiple sclerosis |
| US7459524B1 (en) | 1997-10-02 | 2008-12-02 | Emergent Product Development Gaithersburg Inc. | Chlamydia protein, sequence and uses thereof |
| MXPA01005615A (es) * | 1998-12-04 | 2004-08-19 | Univ Manitoba | Procedimiento de inmunizacion en dos pasos para proteger contra infeccion por chlamydia. |
| US20080213264A1 (en) * | 1998-12-08 | 2008-09-04 | Corixa Corporation | Compounds and methods for treatment and diagnosis of chlamydial infection |
| US20020061848A1 (en) * | 2000-07-20 | 2002-05-23 | Ajay Bhatia | Compounds and methods for treatment and diagnosis of chlamydial infection |
| GB9828000D0 (en) | 1998-12-18 | 1999-02-10 | Chiron Spa | Antigens |
| DE60036698T2 (de) * | 1999-05-03 | 2008-07-24 | Sanofi Pasteur Ltd., Toronto | Chlamydia-antigene und entsprechende dna-fragmente und deren verwendungen |
| ES2303525T3 (es) | 2000-04-21 | 2008-08-16 | Corixa Corporation | Compuestos y metodos para el tratamiento y diagnostico de infeccion por chlamydia. |
| US6919187B2 (en) | 2000-04-21 | 2005-07-19 | Corixa Corporation | Compounds and methods for treatment and diagnosis of chlamydial infection |
| US7731980B2 (en) * | 2000-10-02 | 2010-06-08 | Emergent Product Development Gaithersburg Inc. | Chlamydia PMP proteins, gene sequences and uses thereof |
| US7537772B1 (en) | 2000-10-02 | 2009-05-26 | Emergent Product Development Gaithersburg Inc. | Chlamydia protein, gene sequence and the uses thereof |
| GB0109297D0 (en) | 2001-04-12 | 2001-05-30 | Glaxosmithkline Biolog Sa | Vaccine |
| AU2002366592B2 (en) * | 2001-12-12 | 2008-01-10 | Novartis Vaccines And Diagnostics S.R.L. | Immunisation against Chlamydia trachomatis |
| US7807802B2 (en) | 2002-11-12 | 2010-10-05 | Abbott Lab | Polynucleotides for the amplification and detection of Chlamydia trachomatis and Neisseria gonorrhoeae |
| ITTO20050905A1 (it) * | 2005-12-23 | 2007-06-24 | Univ Degli Studi Torino | Leganti sintetici capaci di legare l'ocratossina e relativi usi |
| EP2486938B1 (en) | 2006-09-26 | 2018-05-09 | Infectious Disease Research Institute | Vaccine composition containing synthetic adjuvant |
| US20090181078A1 (en) | 2006-09-26 | 2009-07-16 | Infectious Disease Research Institute | Vaccine composition containing synthetic adjuvant |
| CN101522218B (zh) | 2006-10-12 | 2012-09-26 | 葛兰素史密丝克莱恩生物有限公司 | 包含水包油乳液佐剂的疫苗 |
| EP2086582B1 (en) | 2006-10-12 | 2012-11-14 | GlaxoSmithKline Biologicals s.a. | Vaccine comprising an oil in water emulsion adjuvant |
| TW200908994A (en) | 2007-04-20 | 2009-03-01 | Glaxosmithkline Biolog Sa | Vaccine |
| US20100310593A1 (en) * | 2007-06-14 | 2010-12-09 | Emergent Product Development Gaithersburg Inc. | Vaccines Against Chlamydia Infection |
| US20090254588A1 (en) * | 2007-06-19 | 2009-10-08 | Zhong Li | Multi-Dimensional Data Merge |
| WO2010005474A1 (en) * | 2008-06-16 | 2010-01-14 | Emergent Product Development Gaithersburg Inc. | Recombinant modified vaccinia virus ankara (mva) expressing chlamydia polypeptide antigens |
| WO2009158240A1 (en) | 2008-06-16 | 2009-12-30 | Emergent Product Development Uk Limited | Salmonella vectored vaccines against chlamydia and methods of use |
| CA2787697C (en) | 2009-01-29 | 2018-03-20 | British Columbia Cancer Agency Branch | Compositions comprising chlamydia antigens |
| MX360448B (es) | 2009-06-05 | 2018-11-01 | Infectious Disease Res Inst | Adyuvantes sinteticos de glucopiranosil-lipido. |
| CA2792679C (en) | 2010-03-09 | 2019-11-12 | Biomedical Research Models, Inc. | A novel mucosal vaccination approach for herpes simplex virus type-2 |
| EA027236B1 (ru) | 2011-04-08 | 2017-07-31 | Иммьюн Дизайн Корп. | Иммуногенные композиции и способы применения таких композиций для индукции гуморального и клеточного иммунного ответа |
| TR201908003T4 (tr) | 2012-02-07 | 2019-06-21 | Infectious Disease Res Inst | TLR4 agonistleri içeren gelişmiş adjuvan formülasyonları ve bunların kullanım metotları. |
| ES2673556T3 (es) | 2012-05-16 | 2018-06-22 | Immune Design Corp. | Vacunas para el VHS-2 |
| AU2014203873A1 (en) | 2013-01-07 | 2015-07-30 | Biomedical Research Models, Inc. | Therapeutic vaccines for treating herpes simplex virus type 2 infections |
| KR102039520B1 (ko) | 2013-04-18 | 2019-11-01 | 이뮨 디자인 코포레이션 | 암 치료에 이용하기 위한 gla 단일요법 |
| US9463198B2 (en) | 2013-06-04 | 2016-10-11 | Infectious Disease Research Institute | Compositions and methods for reducing or preventing metastasis |
| IL310015B1 (en) | 2013-12-31 | 2025-10-01 | Access To Advanced Health Inst | Single vial formulation |
| WO2017176076A1 (en) | 2016-04-06 | 2017-10-12 | Ewha University - Industry Collaboration Foundation | A peptide with ability to penetrate cell membrane |
| DK3458475T3 (da) | 2016-05-16 | 2022-09-12 | Access To Advanced Health Inst | Formulering, der indeholder tlr-agonist, og anvendelsesfremgangsmåder |
| JP7195147B2 (ja) | 2016-05-16 | 2022-12-23 | アクセス ツー アドバンスト ヘルス インスティチュート | Ｐｅｇ化リポソームおよび使用方法 |
| KR102748354B1 (ko) | 2016-06-01 | 2024-12-31 | 액세스 투 어드밴스드 헬스 인스티튜트 | 사이징제를 함유하는 나노명반 입자 |
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| IL319329A (en) | 2022-09-09 | 2025-05-01 | Access To Advanced Health Inst | Immunogenic vaccine composition incorporating saponin |
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1997
- 1997-10-02 US US08/942,596 patent/US7459524B1/en not_active Expired - Fee Related
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1998
- 1998-10-01 AU AU95988/98A patent/AU752426B2/en not_active Ceased
- 1998-10-01 CA CA002305709A patent/CA2305709A1/en not_active Abandoned
- 1998-10-01 WO PCT/US1998/020737 patent/WO1999017741A1/en not_active Ceased
- 1998-10-01 JP JP2000514618A patent/JP2001518489A/ja active Pending
- 1998-10-01 EP EP98949723A patent/EP1019028A4/en not_active Withdrawn
- 1998-10-01 NZ NZ503763A patent/NZ503763A/xx not_active IP Right Cessation
- 1998-10-01 EP EP07015945A patent/EP1862472A3/en not_active Withdrawn
- 1998-10-01 HU HU0004639A patent/HUP0004639A3/hu unknown
- 1998-10-01 CN CN2006100887769A patent/CN1911960B/zh not_active Expired - Fee Related
- 1998-10-01 BR BR9813841-3A patent/BR9813841A/pt active Search and Examination
- 1998-10-01 CN CNB988118173A patent/CN1268637C/zh not_active Expired - Fee Related
- 1998-10-01 KR KR1020007003596A patent/KR100586569B1/ko not_active Expired - Fee Related
- 1998-10-02 ZA ZA989012A patent/ZA989012B/xx unknown
- 1998-10-02 CO CO98057476A patent/CO5050400A1/es unknown
- 1998-10-05 AR ARP980104960A patent/AR018013A1/es unknown
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1999
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2000
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2003
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2004
- 2004-01-27 US US10/766,711 patent/US7534445B2/en not_active Expired - Fee Related
- 2004-09-01 US US10/931,779 patent/US7655246B2/en not_active Expired - Fee Related
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| US6642023B1 (en) | 2003-11-04 |
| US20040067524A1 (en) | 2004-04-08 |
| WO1999017741A1 (en) | 1999-04-15 |
| ZA989012B (en) | 1999-04-12 |
| AU9598898A (en) | 1999-04-27 |
| HUP0004639A2 (hu) | 2001-04-28 |
| CA2305709A1 (en) | 1999-04-15 |
| HK1034187A1 (en) | 2001-10-19 |
| EP1862472A2 (en) | 2007-12-05 |
| EP1019028A1 (en) | 2000-07-19 |
| US7534445B2 (en) | 2009-05-19 |
| AU752426B2 (en) | 2002-09-19 |
| US6887843B1 (en) | 2005-05-03 |
| CO5050400A1 (es) | 2001-06-27 |
| CN1911960B (zh) | 2012-11-07 |
| NZ503763A (en) | 2003-01-31 |
| CN1911960A (zh) | 2007-02-14 |
| BR9813841A (pt) | 2000-10-03 |
| KR100586569B1 (ko) | 2006-06-02 |
| EP1862472A3 (en) | 2008-03-19 |
| US7419807B2 (en) | 2008-09-02 |
| JP2001518489A (ja) | 2001-10-16 |
| CN1283108A (zh) | 2001-02-07 |
| US20050048557A1 (en) | 2005-03-03 |
| HUP0004639A3 (en) | 2004-10-28 |
| US7655246B2 (en) | 2010-02-02 |
| KR20010030902A (ko) | 2001-04-16 |
| SA99191283B1 (ar) | 2006-04-18 |
| US7459524B1 (en) | 2008-12-02 |
| US20040137005A1 (en) | 2004-07-15 |
| EP1019028A4 (en) | 2002-11-20 |
| CN1268637C (zh) | 2006-08-09 |
| AR018013A1 (es) | 2001-10-31 |
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