AR065564A1 - Composiciones farmaceuticas que comprenden un agente calciletico - Google Patents
Composiciones farmaceuticas que comprenden un agente calcileticoInfo
- Publication number
- AR065564A1 AR065564A1 ARP080100861A ARP080100861A AR065564A1 AR 065564 A1 AR065564 A1 AR 065564A1 AR P080100861 A ARP080100861 A AR P080100861A AR P080100861 A ARP080100861 A AR P080100861A AR 065564 A1 AR065564 A1 AR 065564A1
- Authority
- AR
- Argentina
- Prior art keywords
- rapid
- agent
- pharmaceutical composition
- short
- subject
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 5
- 230000001126 calcilytic effect Effects 0.000 abstract 5
- 239000003795 chemical substances by application Substances 0.000 abstract 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 102000003982 Parathyroid hormone Human genes 0.000 abstract 2
- 108090000445 Parathyroid hormone Proteins 0.000 abstract 2
- 238000010521 absorption reaction Methods 0.000 abstract 2
- 239000006184 cosolvent Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000000199 parathyroid hormone Substances 0.000 abstract 2
- 229960001319 parathyroid hormone Drugs 0.000 abstract 2
- 230000036470 plasma concentration Effects 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Endocrinology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- Obesity (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Composicion farmacéutica, la cual comprende un agente calcilítico que, cuando se administra oralmente a un sujeto, induce una liberacion rápida y de corta duracion de hormona paratiroidea en e! plasma. Además se proporciona una composicionfarmacéutica que comprende un agente calcilítico que, cuando se administra oralmente a un sujeto, da como resultado una rápida absorcion del agente calcilítico, con un aumento rápido y de corta duracion subsiguiente de sus niveles en plasma. Ademásse proporciona una composicion farmacéutica que comprende un agente calcilítico que, cuando se administra oralmente a un sujeto, induce una absorcion rápida y de corta duracion del agente calcilítico, y una liberacion rápida de y corta duracion dela hormona paratiroidea. Reivindicacion 7: Una composicion farmacéutica de acuerdo con cualquiera de las reivindicaciones anteriores, la cual comprende además un medio de vehículo que comprende un componente lipofílico, un tensoactivo, y uncomponente hidrofílico. Reivindicacion 8: Una composicion de acuerdo con la reivindicacion 7, en donde el medio de vehículo comprende además un co-solvente. Reivindicacion 12: La composicion de acuerdo con cualquiera de las reivindicaciones 8 a11, en donde el co-solvente comprende etanol.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07103365A EP1964548A1 (en) | 2007-03-02 | 2007-03-02 | Pharmaceutical compositions comprising a calcilytic agent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR065564A1 true AR065564A1 (es) | 2009-06-17 |
Family
ID=38016483
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP080100861A AR065564A1 (es) | 2007-03-02 | 2008-02-29 | Composiciones farmaceuticas que comprenden un agente calciletico |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US20100022565A1 (es) |
| EP (2) | EP1964548A1 (es) |
| JP (1) | JP2010520179A (es) |
| KR (1) | KR20090125245A (es) |
| CN (1) | CN101621993A (es) |
| AR (1) | AR065564A1 (es) |
| AU (1) | AU2008223876A1 (es) |
| CA (1) | CA2678794A1 (es) |
| CL (1) | CL2008000617A1 (es) |
| CO (1) | CO6210808A2 (es) |
| EC (1) | ECSP099611A (es) |
| GT (1) | GT200900235A (es) |
| IL (1) | IL200274A0 (es) |
| MA (1) | MA31201B1 (es) |
| MX (1) | MX2009009343A (es) |
| PE (1) | PE20081794A1 (es) |
| TN (1) | TN2009000358A1 (es) |
| TW (1) | TW200843762A (es) |
| WO (1) | WO2008107390A1 (es) |
| ZA (1) | ZA200905472B (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0606426D0 (en) * | 2006-03-30 | 2006-05-10 | Novartis Ag | Benzimidazole derivatives |
| AU2007303846B2 (en) | 2006-10-04 | 2011-03-10 | Pfizer Products Inc. | Pyrido[4,3-d]pyrimidin-4(3H)-one derivatives as calcium receptor antagonists |
| CA2913731C (en) | 2013-06-04 | 2021-05-25 | Monosol Llc | Water-soluble film sealing solutions, related methods, and related articles |
| CA3064371A1 (en) * | 2016-05-20 | 2017-11-23 | Azure Biotech, Inc. | Vaginal delivery systems containing selective estrogen receptor modulator (serm) and uses thereof |
| JP6994061B2 (ja) | 2019-02-15 | 2022-01-14 | ノバルティス アーゲー | 4-(7-ヒドロキシ-2-イソプロピル-4-オキソ-4h-キナゾリン-3-イル)-ベンゾニトリルの製剤 |
| KR102220255B1 (ko) * | 2019-08-13 | 2021-02-26 | 동국대학교 산학협력단 | 수술 후 부갑상선기능저하증 개선 또는 치료용 약학 조성물 및 이를 이용한 치료 방법 |
| WO2021029517A1 (en) * | 2019-08-13 | 2021-02-18 | Dongguk University Industry-Academic Cooperation Foundation | Pharmaceutical composition for improving or treating post-surgical hypoparathyroidism and treatment method using the same |
| MX2023001438A (es) * | 2020-08-04 | 2023-06-15 | Calcilytix Therapeutics Inc | Formulaciones de compuestos calciliticos de trifenilo. |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7202261B2 (en) * | 1996-12-03 | 2007-04-10 | Nps Pharmaceuticals, Inc. | Calcilytic compounds |
| PE20001456A1 (es) * | 1999-02-02 | 2001-01-28 | Smithkline Beecham Corp | Compuestos calcioliticos |
| US20060052345A1 (en) * | 2002-11-04 | 2006-03-09 | Nps Pharmaceuticals, Inc. | Quinazolinone compounds as calcilytics |
-
2007
- 2007-03-02 EP EP07103365A patent/EP1964548A1/en not_active Ceased
-
2008
- 2008-02-29 AR ARP080100861A patent/AR065564A1/es unknown
- 2008-02-29 PE PE2008000407A patent/PE20081794A1/es not_active Application Discontinuation
- 2008-02-29 MX MX2009009343A patent/MX2009009343A/es not_active Application Discontinuation
- 2008-02-29 AU AU2008223876A patent/AU2008223876A1/en not_active Abandoned
- 2008-02-29 JP JP2009551224A patent/JP2010520179A/ja active Pending
- 2008-02-29 CA CA002678794A patent/CA2678794A1/en not_active Abandoned
- 2008-02-29 US US12/529,359 patent/US20100022565A1/en not_active Abandoned
- 2008-02-29 CL CL200800617A patent/CL2008000617A1/es unknown
- 2008-02-29 TW TW097107238A patent/TW200843762A/zh unknown
- 2008-02-29 EP EP08717280A patent/EP2124893A1/en not_active Withdrawn
- 2008-02-29 KR KR1020097018235A patent/KR20090125245A/ko not_active Withdrawn
- 2008-02-29 CN CN200880006503A patent/CN101621993A/zh active Pending
- 2008-02-29 WO PCT/EP2008/052500 patent/WO2008107390A1/en not_active Ceased
-
2009
- 2009-08-05 ZA ZA200905472A patent/ZA200905472B/xx unknown
- 2009-08-06 IL IL200274A patent/IL200274A0/en unknown
- 2009-08-28 CO CO09091220A patent/CO6210808A2/es not_active Application Discontinuation
- 2009-08-28 TN TNP2009000358A patent/TN2009000358A1/fr unknown
- 2009-08-31 MA MA32187A patent/MA31201B1/fr unknown
- 2009-08-31 GT GT200900235A patent/GT200900235A/es unknown
- 2009-09-01 EC EC2009009611A patent/ECSP099611A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200905472B (en) | 2010-04-28 |
| TN2009000358A1 (en) | 2010-12-31 |
| IL200274A0 (en) | 2010-04-29 |
| WO2008107390A1 (en) | 2008-09-12 |
| ECSP099611A (es) | 2009-10-30 |
| PE20081794A1 (es) | 2009-01-09 |
| GT200900235A (es) | 2010-03-15 |
| AU2008223876A1 (en) | 2008-09-12 |
| US20100022565A1 (en) | 2010-01-28 |
| MX2009009343A (es) | 2009-09-11 |
| CN101621993A (zh) | 2010-01-06 |
| KR20090125245A (ko) | 2009-12-04 |
| MA31201B1 (fr) | 2010-02-01 |
| CA2678794A1 (en) | 2008-09-12 |
| CO6210808A2 (es) | 2010-10-20 |
| JP2010520179A (ja) | 2010-06-10 |
| TW200843762A (en) | 2008-11-16 |
| EP1964548A1 (en) | 2008-09-03 |
| EP2124893A1 (en) | 2009-12-02 |
| CL2008000617A1 (es) | 2008-09-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |