AR059350A1 - Formulacion farmaceutica para aerosoles con dos o mas principios activos y al menos una sustancia tensioactiva - Google Patents
Formulacion farmaceutica para aerosoles con dos o mas principios activos y al menos una sustancia tensioactivaInfo
- Publication number
- AR059350A1 AR059350A1 ARP070100504A ARP070100504A AR059350A1 AR 059350 A1 AR059350 A1 AR 059350A1 AR P070100504 A ARP070100504 A AR P070100504A AR P070100504 A ARP070100504 A AR P070100504A AR 059350 A1 AR059350 A1 AR 059350A1
- Authority
- AR
- Argentina
- Prior art keywords
- aerosols
- pharmaceutical formulation
- active principles
- substance
- propellant
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
- A61K9/124—Aerosols; Foams characterised by the propellant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Otolaryngology (AREA)
- Emergency Medicine (AREA)
- Dispersion Chemistry (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente se refiere a formulaciones farmacéuticas para aerosoles con al menos dos o más principios activos junto con al menos una sustancia tensioactiva para aplicacion inhalativa o nasal. En particular, la presente se refiere a preparaciones farmacéuticas para aerosoles para dosificacion operados con propelente con un hidrocarburo fluorado (HFA) como propelente, que contienen una combinacion de dos o más principios activos, en donde hay al menos un principio activo en forma disuelta además de al menos otro principio activo en forma de partículas suspendidas junto con al menos una sustancia tensioactiva.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102006006207 | 2006-02-09 | ||
| DE102006053374A DE102006053374A1 (de) | 2006-02-09 | 2006-11-10 | Pharmazeutische Formulierung für Aerosole mit zwei oder mehr Wirkstoffen und mindestens einer oberflächenaktiven Substanz |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR059350A1 true AR059350A1 (es) | 2008-03-26 |
Family
ID=38266105
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP070100504A AR059350A1 (es) | 2006-02-09 | 2007-02-07 | Formulacion farmaceutica para aerosoles con dos o mas principios activos y al menos una sustancia tensioactiva |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20070183982A1 (es) |
| EP (1) | EP1988874A2 (es) |
| JP (1) | JP2009526012A (es) |
| KR (1) | KR20080098656A (es) |
| CN (1) | CN102861339A (es) |
| AR (1) | AR059350A1 (es) |
| AU (1) | AU2007213819B2 (es) |
| BR (1) | BRPI0707594A2 (es) |
| CA (1) | CA2641883A1 (es) |
| DE (1) | DE102006053374A1 (es) |
| EA (1) | EA014776B1 (es) |
| EC (1) | ECSP088653A (es) |
| IL (1) | IL193274A0 (es) |
| NO (1) | NO20083375L (es) |
| NZ (1) | NZ571016A (es) |
| PE (2) | PE20070951A1 (es) |
| TW (1) | TW200800294A (es) |
| UY (1) | UY30139A1 (es) |
| WO (1) | WO2007090822A2 (es) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA06015204A (es) * | 2004-07-02 | 2007-03-15 | Boehringer Ingelheim Int | Formulaciones en suspension de aerosol con tg 227 ea o tg 134 a como agentes propulsores. |
| DE102006017320A1 (de) * | 2006-04-11 | 2007-10-18 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Aerosolsuspensionsformulierungen mit TG 227 ea oder TG 134 a als Treibmittel |
| GB0712454D0 (en) | 2007-06-27 | 2007-08-08 | Generics Uk Ltd | Pharmaceutical compositions |
| EP2077132A1 (en) | 2008-01-02 | 2009-07-08 | Boehringer Ingelheim Pharma GmbH & Co. KG | Dispensing device, storage device and method for dispensing a formulation |
| JP5670421B2 (ja) | 2009-03-31 | 2015-02-18 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | コンポーネント表面のコーティング方法 |
| EP2432531B1 (de) | 2009-05-18 | 2019-03-06 | Boehringer Ingelheim International GmbH | Adapter, inhalationseinrichtung und zerstäuber |
| WO2011064164A1 (en) | 2009-11-25 | 2011-06-03 | Boehringer Ingelheim International Gmbh | Nebulizer |
| US10016568B2 (en) | 2009-11-25 | 2018-07-10 | Boehringer Ingelheim International Gmbh | Nebulizer |
| JP5658268B2 (ja) | 2009-11-25 | 2015-01-21 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ネブライザ |
| WO2011160932A1 (en) | 2010-06-24 | 2011-12-29 | Boehringer Ingelheim International Gmbh | Nebulizer |
| WO2012087094A1 (es) * | 2010-12-21 | 2012-06-28 | Techsphere S.A. De C.V. | Composición farmacéutica inhalable para el tratamiento del asma por administración vía aérea mediante un succionador de emulación de aerosol |
| EP2694220B1 (de) | 2011-04-01 | 2020-05-06 | Boehringer Ingelheim International GmbH | Medizinisches gerät mit behälter |
| US9827384B2 (en) | 2011-05-23 | 2017-11-28 | Boehringer Ingelheim International Gmbh | Nebulizer |
| WO2013152894A1 (de) | 2012-04-13 | 2013-10-17 | Boehringer Ingelheim International Gmbh | Zerstäuber mit kodiermitteln |
| GB201306984D0 (en) * | 2013-04-17 | 2013-05-29 | Mexichem Amanco Holding Sa | Composition |
| PL2835146T3 (pl) | 2013-08-09 | 2021-04-06 | Boehringer Ingelheim International Gmbh | Nebulizator |
| EP3030298B1 (en) | 2013-08-09 | 2017-10-11 | Boehringer Ingelheim International GmbH | Nebulizer |
| RU2536253C1 (ru) * | 2013-10-09 | 2014-12-20 | Шолекс Девелопмент Гмбх | Комбинированный аэрозольный препарат для лечения болезней органов дыхания |
| LT4242916T (lt) | 2014-05-07 | 2025-12-29 | Boehringer Ingelheim International Gmbh | Purkštuvas |
| EA032850B1 (ru) | 2014-05-07 | 2019-07-31 | Бёрингер Ингельхайм Интернациональ Гмбх | Контейнер, небулайзер и способ изготовления контейнера |
| ES2874029T3 (es) | 2014-05-07 | 2021-11-04 | Boehringer Ingelheim Int | Nebulizador |
| EP2985019B1 (en) | 2014-08-16 | 2021-10-20 | Church & Dwight Co., Inc. | Nasal composition having anti-viral properties |
| WO2016164508A1 (en) * | 2015-04-10 | 2016-10-13 | 3M Innovative Properties Company | Formulation and aerosol canisters, inhalers, and the like containing the formulation |
| GB2573297A (en) * | 2018-04-30 | 2019-11-06 | Mexichem Fluor Sa De Cv | Pharmaceutical composition |
| CN110876723A (zh) * | 2018-09-06 | 2020-03-13 | 天津金耀集团有限公司 | 一种含有表面活性剂的异丙托溴铵喷雾剂 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1230472A (es) * | 1967-07-10 | 1971-05-05 | ||
| ATE60226T1 (de) * | 1986-03-10 | 1991-02-15 | Kurt Burghart | Pharmazeutikum sowie verfahren zu seiner herstellung. |
| AU2178392A (en) * | 1991-06-12 | 1993-01-12 | Minnesota Mining And Manufacturing Company | Albuterol sulfate suspension aerosol formulations |
| US5503869A (en) * | 1994-10-21 | 1996-04-02 | Glaxo Wellcome Inc. | Process for forming medicament carrier for dry powder inhalator |
| ATE236617T1 (de) * | 1994-12-22 | 2003-04-15 | Astrazeneca Ab | Aerosol-arzneiformulierungen |
| US6392962B1 (en) * | 1995-05-18 | 2002-05-21 | Rmp, Inc. | Method of sleep time measurement |
| GB9626960D0 (en) * | 1996-12-27 | 1997-02-12 | Glaxo Group Ltd | Valve for aerosol container |
| GB2332372B (en) * | 1997-12-08 | 2002-08-14 | Minnesota Mining & Mfg | Pharmaceutical aerosol compositions |
| US6423298B2 (en) * | 1998-06-18 | 2002-07-23 | Boehringer Ingelheim Pharmaceuticals, Inc. | Pharmaceutical formulations for aerosols with two or more active substances |
| HU229064B1 (en) * | 1998-06-18 | 2013-07-29 | Boehringer Ingelheim Pharma | Pharmaceutical formulations for aerosols with two or more active substances |
| US6352152B1 (en) * | 1998-12-18 | 2002-03-05 | Smithkline Beecham Corporation | Method and package for storing a pressurized container containing a drug |
| US20040092428A1 (en) * | 2001-11-27 | 2004-05-13 | Hongming Chen | Oral pharmaceuticals formulation comprising paclitaxel, derivatives and methods of administration thereof |
| SE0200312D0 (sv) * | 2002-02-01 | 2002-02-01 | Astrazeneca Ab | Novel composition |
| GB0207899D0 (en) * | 2002-04-05 | 2002-05-15 | 3M Innovative Properties Co | Formoterol and cielesonide aerosol formulations |
| EP2319584A1 (en) * | 2002-08-29 | 2011-05-11 | Cipla Ltd. | Pharmaceutical products and compositions comprising salmeterol, ciclesonide and tiotropium |
| ME00420B (me) * | 2003-03-20 | 2011-12-20 | Boehringer Ingelheim Pharmaceuticals Inc | Formulacija, za inhalator u kojem se odmjerava doza, u kojoj se kao propelenti koriste hidro-fluoro-alkani |
| US20050191246A1 (en) * | 2003-12-13 | 2005-09-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Powders comprising low molecular dextran and methods of producing those powders |
| US20050239778A1 (en) * | 2004-04-22 | 2005-10-27 | Boehringer Ingelheim International Gmbh | Novel medicament combinations for the treatment of respiratory diseases |
| US7723306B2 (en) * | 2004-05-10 | 2010-05-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Spray-dried powder comprising at least one 1,4 O-linked saccharose-derivative and methods for their preparation |
| US7727962B2 (en) * | 2004-05-10 | 2010-06-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Powder comprising new compositions of oligosaccharides and methods for their preparation |
| US7611709B2 (en) * | 2004-05-10 | 2009-11-03 | Boehringer Ingelheim Pharma Gmbh And Co. Kg | 1,4 O-linked saccharose derivatives for stabilization of antibodies or antibody derivatives |
| MXPA06015204A (es) * | 2004-07-02 | 2007-03-15 | Boehringer Ingelheim Int | Formulaciones en suspension de aerosol con tg 227 ea o tg 134 a como agentes propulsores. |
-
2006
- 2006-11-10 DE DE102006053374A patent/DE102006053374A1/de not_active Withdrawn
-
2007
- 2007-01-29 US US11/668,123 patent/US20070183982A1/en not_active Abandoned
- 2007-02-06 EP EP07704378A patent/EP1988874A2/de not_active Withdrawn
- 2007-02-06 AU AU2007213819A patent/AU2007213819B2/en not_active Expired - Fee Related
- 2007-02-06 JP JP2008553744A patent/JP2009526012A/ja active Pending
- 2007-02-06 EA EA200801767A patent/EA014776B1/ru not_active IP Right Cessation
- 2007-02-06 CA CA002641883A patent/CA2641883A1/en not_active Abandoned
- 2007-02-06 CN CN201210380794XA patent/CN102861339A/zh active Pending
- 2007-02-06 BR BRPI0707594-4A patent/BRPI0707594A2/pt not_active IP Right Cessation
- 2007-02-06 WO PCT/EP2007/051095 patent/WO2007090822A2/de not_active Ceased
- 2007-02-06 NZ NZ571016A patent/NZ571016A/en not_active IP Right Cessation
- 2007-02-06 KR KR1020087022075A patent/KR20080098656A/ko not_active Ceased
- 2007-02-07 PE PE2007000132A patent/PE20070951A1/es not_active Application Discontinuation
- 2007-02-07 AR ARP070100504A patent/AR059350A1/es not_active Application Discontinuation
- 2007-02-07 PE PE2011001533A patent/PE20120023A1/es not_active Application Discontinuation
- 2007-02-08 UY UY30139A patent/UY30139A1/es not_active Application Discontinuation
- 2007-02-08 TW TW096104535A patent/TW200800294A/zh unknown
-
2008
- 2008-07-29 EC EC2008008653A patent/ECSP088653A/es unknown
- 2008-08-04 NO NO20083375A patent/NO20083375L/no not_active Application Discontinuation
- 2008-08-06 IL IL193274A patent/IL193274A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2009526012A (ja) | 2009-07-16 |
| DE102006053374A1 (de) | 2007-08-16 |
| BRPI0707594A2 (pt) | 2011-05-10 |
| IL193274A0 (en) | 2009-08-03 |
| EP1988874A2 (de) | 2008-11-12 |
| KR20080098656A (ko) | 2008-11-11 |
| ECSP088653A (es) | 2008-10-31 |
| CN102861339A (zh) | 2013-01-09 |
| WO2007090822A2 (de) | 2007-08-16 |
| NO20083375L (no) | 2008-10-30 |
| TW200800294A (en) | 2008-01-01 |
| PE20070951A1 (es) | 2007-09-24 |
| EA014776B1 (ru) | 2011-02-28 |
| CA2641883A1 (en) | 2007-08-16 |
| US20070183982A1 (en) | 2007-08-09 |
| AU2007213819B2 (en) | 2012-11-15 |
| UY30139A1 (es) | 2007-09-28 |
| EA200801767A1 (ru) | 2009-02-27 |
| AU2007213819A1 (en) | 2007-08-16 |
| NZ571016A (en) | 2012-01-12 |
| WO2007090822A3 (de) | 2007-11-08 |
| PE20120023A1 (es) | 2012-02-13 |
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