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AR057096A1 - PROCESS TO PREPARE SACARINIC ACIDS AND LACTONS - Google Patents

PROCESS TO PREPARE SACARINIC ACIDS AND LACTONS

Info

Publication number
AR057096A1
AR057096A1 ARP060103721A ARP060103721A AR057096A1 AR 057096 A1 AR057096 A1 AR 057096A1 AR P060103721 A ARP060103721 A AR P060103721A AR P060103721 A ARP060103721 A AR P060103721A AR 057096 A1 AR057096 A1 AR 057096A1
Authority
AR
Argentina
Prior art keywords
sacarinic
lactons
acids
prepare
saccharinic
Prior art date
Application number
ARP060103721A
Other languages
Spanish (es)
Inventor
David Hotchkiss
George Fleet
Thomas Heinz
Richard Storer
Original Assignee
Chancellors Masters And Schola
Novartis Ag
Idenix Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chancellors Masters And Schola, Novartis Ag, Idenix Pharmaceuticals Inc filed Critical Chancellors Masters And Schola
Publication of AR057096A1 publication Critical patent/AR057096A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)

Abstract

Se divulga un proceso mejorado para preparar un ácido sacarínico o una lactona sacarínica, que utiliza la bien conocida reaccion de rearreglo de Amadori. La síntesis utiliza azucares protegidos o desprotegidos o sus análogos como materiales de partida, y reactivos no utilizados anteriormente para entregar rendimientos aumentados de producto en un tiempo de reaccion inferior.An improved process for preparing a saccharinic acid or a saccharinic lactone is disclosed, which uses the well-known Amadori rearrangement reaction. The synthesis uses protected or unprotected sugars or their analogs as starting materials, and reagents not previously used to deliver increased product yields in a lower reaction time.

ARP060103721A 2005-08-26 2006-08-25 PROCESS TO PREPARE SACARINIC ACIDS AND LACTONS AR057096A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71193405P 2005-08-26 2005-08-26

Publications (1)

Publication Number Publication Date
AR057096A1 true AR057096A1 (en) 2007-11-14

Family

ID=37772543

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP060103721A AR057096A1 (en) 2005-08-26 2006-08-25 PROCESS TO PREPARE SACARINIC ACIDS AND LACTONS

Country Status (3)

Country Link
AR (1) AR057096A1 (en)
UY (1) UY29769A1 (en)
WO (1) WO2007025304A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY164523A (en) 2000-05-23 2017-12-29 Univ Degli Studi Cagliari Methods and compositions for treating hepatitis c virus
EA007867B1 (en) 2000-05-26 2007-02-27 Айденикс (Кайман) Лимитед Methods and compositions for treating flaviviruses and pestiviruses
NZ537662A (en) 2002-06-28 2007-10-26 Idenix Cayman Ltd 2'-C-methyl-3'-O-L-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections
CN1678326A (en) 2002-06-28 2005-10-05 埃迪尼克斯(开曼)有限公司 2'-C-methyl-3'-O-L-valine ester ribofuranocytidine for the treatment of flavivirus infection
DK1576138T3 (en) 2002-11-15 2017-05-01 Idenix Pharmaceuticals Llc 2'-METHYL NUCLEOSIDES IN COMBINATION WITH INTERFERON AND FLAVIVIRIDAE MUTATION
PL377287A1 (en) 2002-12-12 2006-01-23 Idenix (Cayman) Limited Process for the production of 2'-branched nucleosides
JP5342887B2 (en) * 2009-01-29 2013-11-13 花王株式会社 Method for producing α-aminoketone compound
KR20150028808A (en) 2012-06-13 2015-03-16 브리스톨-마이어스 스큅 컴퍼니 Process for the preparation of 2-c-methyl-d-ribonic-gamma-lactone
CN104693158B (en) * 2015-02-15 2017-03-29 上海应用技术学院 A kind of method for preparing 2 C methyl D ribonic acids, 1,4 lactone
CN104693157A (en) * 2015-02-15 2015-06-10 上海应用技术学院 Preparation method of 2-C-methyl-D-ribotide-1,4-lactone

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITFI20030033A1 (en) * 2003-02-10 2004-08-11 Inalco Spa PROCESS FOR THE PREPARATION OF RIBOFURANOSIDIC DERIVATIVES

Also Published As

Publication number Publication date
WO2007025304A2 (en) 2007-03-01
WO2007025304A3 (en) 2007-05-31
UY29769A1 (en) 2007-02-28

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