AR054336A1 - Tratamiento de enfermedades dermatologicas y del prurito - Google Patents
Tratamiento de enfermedades dermatologicas y del pruritoInfo
- Publication number
- AR054336A1 AR054336A1 ARP060101247A ARP060101247A AR054336A1 AR 054336 A1 AR054336 A1 AR 054336A1 AR P060101247 A ARP060101247 A AR P060101247A AR P060101247 A ARP060101247 A AR P060101247A AR 054336 A1 AR054336 A1 AR 054336A1
- Authority
- AR
- Argentina
- Prior art keywords
- treatment
- dermatological
- diseases
- tyrosine kinase
- prurite
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 3
- 102000011017 Type 4 Cyclic Nucleotide Phosphodiesterases Human genes 0.000 abstract 2
- 108010037584 Type 4 Cyclic Nucleotide Phosphodiesterases Proteins 0.000 abstract 2
- 201000004624 Dermatitis Diseases 0.000 abstract 1
- 206010012438 Dermatitis atopic Diseases 0.000 abstract 1
- 206010012442 Dermatitis contact Diseases 0.000 abstract 1
- 208000003251 Pruritus Diseases 0.000 abstract 1
- 102000000551 Syk Kinase Human genes 0.000 abstract 1
- 108010016672 Syk Kinase Proteins 0.000 abstract 1
- 108010046882 ZAP-70 Protein-Tyrosine Kinase Proteins 0.000 abstract 1
- 102000007624 ZAP-70 Protein-Tyrosine Kinase Human genes 0.000 abstract 1
- 201000008937 atopic dermatitis Diseases 0.000 abstract 1
- 208000010668 atopic eczema Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000010247 contact dermatitis Diseases 0.000 abstract 1
- 230000003960 inflammatory cascade Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- OFPXSFXSNFPTHF-UHFFFAOYSA-N oxaprozin Chemical compound O1C(CCC(=O)O)=NC(C=2C=CC=CC=2)=C1C1=CC=CC=C1 OFPXSFXSNFPTHF-UHFFFAOYSA-N 0.000 abstract 1
- 229960002739 oxaprozin Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/421—1,3-Oxazoles, e.g. pemoline, trimethadione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/49—Cinchonan derivatives, e.g. quinine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Principio para el tratamiento de enfermedades dermatologicas, que comprende inhibir varios pasos cruciales de la cascada inflamatoria, incluyendo por lo menos la inhibicion de la proteína tirosina quinasa SYK, la proteína tirosina quinasa ZAP-70 y la fosfodiesterasa IV (PDE-IV) mediante la administracion por vía sistémica o topica en la piel de una cantidad eficaz de oxaprozina o de un compuesto estrechamente relacionado. La presente es particularmente util para el tratamiento de eczemas, tales como dermatitis de contacto y dermatitis atopica, y para el tratamiento del prurito. La presente también suministra composiciones dermatologicas para usar en el tratamiento de una enfermedad dermatologica.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200500437 | 2005-03-30 | ||
| DKPA200500438 | 2005-03-30 | ||
| DKPA200500949 | 2005-06-27 | ||
| DKPA200500948 | 2005-06-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR054336A1 true AR054336A1 (es) | 2007-06-20 |
Family
ID=38218953
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP060101247A AR054336A1 (es) | 2005-03-30 | 2006-03-30 | Tratamiento de enfermedades dermatologicas y del prurito |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US20060251689A1 (es) |
| AR (1) | AR054336A1 (es) |
| PE (1) | PE20061303A1 (es) |
| TW (1) | TW200722087A (es) |
| UY (1) | UY29449A1 (es) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6809118B2 (en) * | 2002-07-25 | 2004-10-26 | Yih-Lin Chung | Methods for therapy of radiation cutaneous syndrome |
| US8846039B2 (en) * | 2002-04-26 | 2014-09-30 | Asan Laboratories Company (Cayman), Limited | Method for ameliorating pruritus |
| US20060275370A1 (en) * | 2002-07-25 | 2006-12-07 | Yih-Lin Chung | Method and compositions for treatment of epithelial damage |
| US8163764B2 (en) * | 2002-04-26 | 2012-04-24 | Asan Laboratories Company (Cayman) Limited | Skincare methods |
| US8946295B2 (en) * | 2002-07-25 | 2015-02-03 | Sunny Pharmtech Inc. | Histone hyperacetylating agents for promoting wound healing and preventing scar formation |
| KR101456815B1 (ko) * | 2005-02-16 | 2014-10-31 | 아나코르 파마슈티칼스 인코포레이티드 | 보론함유 소분자 |
| CN106008583A (zh) | 2005-12-30 | 2016-10-12 | 安纳考尔医药公司 | 含硼的小分子 |
| PL1988779T3 (pl) * | 2006-02-16 | 2015-10-30 | Anacor Pharmaceuticals Inc | Małe cząsteczki zawierające bor jako środki przeciwzapalne |
| US20080107743A1 (en) * | 2006-11-02 | 2008-05-08 | Akpharma Inc. | Composition and method for enhancing skin cell growth, proliferation and repair |
| EP3162787A1 (en) * | 2007-03-20 | 2017-05-03 | Evolva, Inc. | Compositions comprising 5-epi-beta-vetivone, and its use as a fragrance |
| US8124811B2 (en) | 2007-03-20 | 2012-02-28 | Allylix, Inc. | Fragrance and methods for production of 5-epi-β-vetivone, 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-2,6-dien-8-one, and 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-1,6-dien-8-one |
| CA2866527C (en) * | 2007-10-10 | 2018-07-03 | Bryan B. Fuller | Use of isoeugenol esters in treating hyperpigmentation |
| US9616006B2 (en) | 2007-10-10 | 2017-04-11 | DermaMedics, LLC | Methods and compositions for treating dermatological diseases and conditions |
| FR2924349B1 (fr) | 2007-12-03 | 2010-01-01 | Dbv Tech | Methode de desensibilitation aux allergenes |
| JP2015178508A (ja) * | 2008-01-09 | 2015-10-08 | アナコール ファーマシューティカルズ,インコーポレイテッド | 抗炎症剤としてのホウ素含有小分子 |
| JP5745279B2 (ja) * | 2008-01-09 | 2015-07-08 | アナコール ファーマシューティカルズ,インコーポレイテッド | 抗炎症剤としてのホウ素含有小分子 |
| DE102008006393A1 (de) * | 2008-01-28 | 2009-07-30 | Beiersdorf Ag | Verwendung von Lipidkomponenten gegen Pollenallergien |
| EP2187893A4 (en) * | 2008-03-06 | 2012-02-22 | Anacor Pharmaceuticals Inc | SMALL BORON-CONTAINING MOLECULES AS ANTI-INFLAMMATORY AGENTS |
| AU2009221793B2 (en) | 2008-03-06 | 2015-02-19 | Anacor Pharmaceuticals, Inc | Boron-containing small molecules as anti-inflammatory agents |
| WO2009140309A2 (en) * | 2008-05-12 | 2009-11-19 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules |
| WO2010027975A1 (en) * | 2008-09-04 | 2010-03-11 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules |
| US8461336B2 (en) | 2008-09-04 | 2013-06-11 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules |
| US9493489B2 (en) * | 2008-10-15 | 2016-11-15 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules as anti-protozoal agents |
| CA2744231A1 (en) * | 2008-12-17 | 2010-07-15 | Anacor Pharmaceuticals, Inc. | Polymorphs of (s)-3-aminomethyl-7-(3-hydroxy-propoxy)-3h-benzo[c][1,2] oxaborol-1-ol |
| JP2012520267A (ja) * | 2009-03-13 | 2012-09-06 | デベヴェ・テクノロジーズ | 湿疹を処置する方法 |
| AU2010281439A1 (en) * | 2009-07-28 | 2012-03-15 | Anacor Pharmaceuticals, Inc. | Trisubstituted boron-containing molecules |
| WO2011019618A1 (en) | 2009-08-14 | 2011-02-17 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules as antiprotozoal agents |
| WO2011022337A1 (en) * | 2009-08-19 | 2011-02-24 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules as antiprotozoal agents |
| WO2011037731A1 (en) * | 2009-09-25 | 2011-03-31 | Anacor Pharmaceuticals, Inc. | Boron containing small molecules |
| US9346834B2 (en) | 2009-10-20 | 2016-05-24 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules as antiprotozoal agents |
| WO2011060196A1 (en) * | 2009-11-11 | 2011-05-19 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules |
| WO2011094450A1 (en) | 2010-01-27 | 2011-08-04 | Anacor Pharmaceuticals, Inc | Boron-containing small molecules |
| CA2789276A1 (en) | 2010-02-09 | 2011-08-18 | Drexel University | New signaling molecule involved in ultraviolet damage to skin |
| AP2012006482A0 (en) | 2010-03-19 | 2012-10-31 | Anacor Pharmacueticals Inc | Boron-containing small molecules as anti-protozoalagent |
| IT1406067B1 (it) * | 2010-07-14 | 2014-02-06 | Torino Politecnico | Composizioni eudermiche. |
| WO2012033858A2 (en) | 2010-09-07 | 2012-03-15 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules |
| WO2017007668A1 (en) * | 2015-07-08 | 2017-01-12 | Elliptical Therapeutics, Llc | Improved topical ketoprofen formulations |
| US11447506B2 (en) | 2016-05-09 | 2022-09-20 | Anacor Pharmaceuticals, Inc. | Crystal forms of crisaborole in free form and preparation method and use thereof |
| EP3315488A1 (en) * | 2016-10-28 | 2018-05-02 | Elé Corporation | Amino acid based amphoteric surfactant |
| WO2018201131A1 (en) * | 2017-04-28 | 2018-11-01 | Asana Biosciences, Llc | Formulations, methods, kits, and dosage forms for treating atopic dermatitis and for improved stability of an active pharmaceutical ingredient |
| KR20200025244A (ko) * | 2018-08-29 | 2020-03-10 | 연세대학교 산학협력단 | 푸니칼라진을 포함하는 소양증 예방, 개선 또는 치료용 조성물 |
| KR20220124753A (ko) * | 2020-01-08 | 2022-09-14 | 프린시피아 바이오파마, 인코퍼레이티드 | 2-[3-[4-아미노-3-(2-플루오로-4-페녹시-페닐)-1H-피라졸로[3,4-d]피리미딘-1-일]피페리딘-1-카보닐]-4,4-디메틸펜트-2-엔니트릴을 포함하는 국소 약제학적 조성물 |
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| IE52909B1 (en) * | 1981-04-28 | 1988-04-13 | Wyeth John & Brother Ltd | Oxazole derivatives |
| US4659728A (en) * | 1985-02-25 | 1987-04-21 | American Home Products Corporation | Hydroxy substituted 4,5-diphenyl-2-oxazole propanoic acid |
| US4773023A (en) * | 1985-04-12 | 1988-09-20 | Giardina Joseph J | Apparatus for measuring the rate of heat dissipation |
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| FR2765338B1 (fr) * | 1997-06-25 | 1999-07-23 | Inst Francais Du Petrole | Dispositif de prelevement et/ou d'injection d'un echantillon de fluide permettant de conserver l'equilibre chimique et/ou thermodynamique |
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| US20030232091A1 (en) * | 2002-06-17 | 2003-12-18 | Adi Shefer | Stabilized retinol for cosmetic dermatological, and pharmaceutical compositions, and use thereof |
| US20040186182A1 (en) * | 2002-12-18 | 2004-09-23 | Algorx | Administration of capsaicinoids |
| AU2003297397A1 (en) * | 2002-12-19 | 2004-07-14 | Pharmacia Corp | Methods and compositions for the treatment of herpes virus infections using cyclooxygenase-2 selective inhibitors or cyclooxygenase-2 inhibitors in combination with antiviral agents |
| CN1798568B (zh) * | 2003-04-04 | 2011-05-11 | 尤尼根制药公司 | 用于哺乳动物皮肤护理的双重环氧合酶(cox)以及脂氧合酶(lox)抑制剂的组合物 |
| US6852713B2 (en) * | 2003-04-16 | 2005-02-08 | Adolor Corporation | Lactam derivatives and methods of their use |
-
2006
- 2006-03-30 US US11/392,944 patent/US20060251689A1/en not_active Abandoned
- 2006-03-30 US US11/392,938 patent/US20060222671A1/en not_active Abandoned
- 2006-03-30 AR ARP060101247A patent/AR054336A1/es unknown
- 2006-03-30 PE PE2006000350A patent/PE20061303A1/es not_active Application Discontinuation
- 2006-03-30 US US11/392,941 patent/US20060229347A1/en not_active Abandoned
- 2006-03-30 UY UY29449A patent/UY29449A1/es not_active Application Discontinuation
- 2006-03-30 TW TW095111185A patent/TW200722087A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TW200722087A (en) | 2007-06-16 |
| PE20061303A1 (es) | 2006-12-07 |
| US20060229347A1 (en) | 2006-10-12 |
| UY29449A1 (es) | 2006-10-02 |
| US20060222671A1 (en) | 2006-10-05 |
| US20060251689A1 (en) | 2006-11-09 |
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