AR042140A1 - Composiciones para el tratamiento y profilaxis de infecciones por micobacterias - Google Patents
Composiciones para el tratamiento y profilaxis de infecciones por micobacteriasInfo
- Publication number
- AR042140A1 AR042140A1 ARP030104344A ARP030104344A AR042140A1 AR 042140 A1 AR042140 A1 AR 042140A1 AR P030104344 A ARP030104344 A AR P030104344A AR P030104344 A ARP030104344 A AR P030104344A AR 042140 A1 AR042140 A1 AR 042140A1
- Authority
- AR
- Argentina
- Prior art keywords
- compositions
- activity against
- mycobacteria
- prophylaxis
- treatment
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 8
- 208000015181 infectious disease Diseases 0.000 title abstract 2
- 238000011321 prophylaxis Methods 0.000 title abstract 2
- 238000011282 treatment Methods 0.000 title abstract 2
- 230000000694 effects Effects 0.000 abstract 3
- 230000003248 secreting effect Effects 0.000 abstract 2
- 208000035473 Communicable disease Diseases 0.000 abstract 1
- 102000010445 Lactoferrin Human genes 0.000 abstract 1
- 108010063045 Lactoferrin Proteins 0.000 abstract 1
- 206010062207 Mycobacterial infection Diseases 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 230000002238 attenuated effect Effects 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000002955 immunomodulating agent Substances 0.000 abstract 1
- 229940121354 immunomodulator Drugs 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- CSSYQJWUGATIHM-IKGCZBKSSA-N l-phenylalanyl-l-lysyl-l-cysteinyl-l-arginyl-l-arginyl-l-tryptophyl-l-glutaminyl-l-tryptophyl-l-arginyl-l-methionyl-l-lysyl-l-lysyl-l-leucylglycyl-l-alanyl-l-prolyl-l-seryl-l-isoleucyl-l-threonyl-l-cysteinyl-l-valyl-l-arginyl-l-arginyl-l-alanyl-l-phenylal Chemical compound C([C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)C1=CC=CC=C1 CSSYQJWUGATIHM-IKGCZBKSSA-N 0.000 abstract 1
- 229940078795 lactoferrin Drugs 0.000 abstract 1
- 235000021242 lactoferrin Nutrition 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 208000027531 mycobacterial infectious disease Diseases 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
- C07K16/1289—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Mycobacteriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Abstract
Control de enfermedades infecciosas causadas por micobacterias, basados en la administración por vía de mucosas y otras vías de composiciones de anticuerpos para la profilaxis y terapéutica. Composiciones de anticuerpos humanos de clase IgG, IgA secretoria o mezclas de ambos con actividad específica contra antígenos de micobacteria para la prevención y tratamiento de infecciones causadas por este tipo de microorganismo. Dichas composiciones demostraron su capacidad de inhibir la infección por micobacterias "in vivo". Uso de dichas composiciones en combinación con drogas con actividad contra micobacterias. Reivindicación 1: Composición contra micobacterias porque contiene: a) anticuerpos humanos policlonales del tipo IgG o IgA secretoria o la mezcla de ambos con actividad contra componente de micobacterias; b) un vehículo farmacéutico adecuado; y c) eventualmente un componente seleccionado del grupo que comprende inmunomoduladores, cualquier combinación de cepas inactivas o atenuadas o lactoferrina.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CU20020275A CU23406A1 (es) | 2002-11-25 | 2002-11-25 | Composiciones contienendo anticuerpos humanos para el tratamiento y profiláxis de infecciones por micobacterias |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR042140A1 true AR042140A1 (es) | 2005-06-08 |
Family
ID=32331941
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP030104344A AR042140A1 (es) | 2002-11-25 | 2003-11-25 | Composiciones para el tratamiento y profilaxis de infecciones por micobacterias |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20060222642A1 (es) |
| EP (1) | EP1582218B1 (es) |
| CN (1) | CN100579581C (es) |
| AR (1) | AR042140A1 (es) |
| AU (1) | AU2003285261A1 (es) |
| BR (1) | BR0316558A (es) |
| CA (1) | CA2507338A1 (es) |
| CU (1) | CU23406A1 (es) |
| DE (1) | DE60324466D1 (es) |
| MX (1) | MXPA05005669A (es) |
| MY (1) | MY143402A (es) |
| RU (1) | RU2350352C2 (es) |
| WO (1) | WO2004047865A1 (es) |
| ZA (1) | ZA200504773B (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1664119A1 (en) | 2003-09-08 | 2006-06-07 | Medical Research Council | Method for the treatment or prophylaxis of tuberculosis |
| KR101707291B1 (ko) | 2012-02-29 | 2017-02-15 | 오쓰까 세이야꾸 가부시키가이샤 | 항리포아라비노만난 항체 및 당해 항체를 사용한 항산균증의 이뮤노어세이 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816563A (en) * | 1983-11-25 | 1989-03-28 | Amtron, Inc. | Process for obtaining transfer factor from colostrum, transfer factor so obtained and use thereof |
| US5258177A (en) * | 1991-12-10 | 1993-11-02 | Alpha Therapeutic Corporation | IgA preparation and process of making the same |
| US20010007660A1 (en) * | 1997-06-04 | 2001-07-12 | Aharona Glatman-Freedman | Methods of treating and protecting against tuberculosis using a monoclonal antibody selective for mycobacterium tuberculosis |
| AU8063798A (en) * | 1997-06-19 | 1999-01-04 | Regents Of The University Of California, The | Secretory immunoglobulin produced by single cells and methods for making and using same |
-
2002
- 2002-11-25 CU CU20020275A patent/CU23406A1/es unknown
-
2003
- 2003-11-24 MY MYPI20034528A patent/MY143402A/en unknown
- 2003-11-25 AR ARP030104344A patent/AR042140A1/es unknown
- 2003-11-25 MX MXPA05005669A patent/MXPA05005669A/es active IP Right Grant
- 2003-11-25 BR BR0316558-2A patent/BR0316558A/pt not_active IP Right Cessation
- 2003-11-25 EP EP03778232A patent/EP1582218B1/en not_active Expired - Lifetime
- 2003-11-25 US US10/536,298 patent/US20060222642A1/en not_active Abandoned
- 2003-11-25 DE DE60324466T patent/DE60324466D1/de not_active Expired - Lifetime
- 2003-11-25 CN CN200380109162A patent/CN100579581C/zh not_active Expired - Fee Related
- 2003-11-25 WO PCT/CU2003/000015 patent/WO2004047865A1/es not_active Ceased
- 2003-11-25 RU RU2005119995/15A patent/RU2350352C2/ru not_active IP Right Cessation
- 2003-11-25 CA CA002507338A patent/CA2507338A1/en not_active Abandoned
- 2003-11-25 AU AU2003285261A patent/AU2003285261A1/en not_active Abandoned
-
2005
- 2005-06-10 ZA ZA200504773A patent/ZA200504773B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003285261A1 (en) | 2004-06-18 |
| EP1582218B1 (en) | 2008-10-29 |
| CU23406A1 (es) | 2009-08-04 |
| DE60324466D1 (de) | 2008-12-11 |
| MXPA05005669A (es) | 2006-02-22 |
| CN1756565A (zh) | 2006-04-05 |
| CA2507338A1 (en) | 2004-06-10 |
| CN100579581C (zh) | 2010-01-13 |
| BR0316558A (pt) | 2005-10-04 |
| WO2004047865A1 (es) | 2004-06-10 |
| MY143402A (en) | 2011-05-13 |
| US20060222642A1 (en) | 2006-10-05 |
| RU2350352C2 (ru) | 2009-03-27 |
| EP1582218A1 (en) | 2005-10-05 |
| RU2005119995A (ru) | 2006-03-20 |
| ZA200504773B (en) | 2007-12-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |