AR042037A1 - Profarmaco de celecoxib - Google Patents
Profarmaco de celecoxibInfo
- Publication number
- AR042037A1 AR042037A1 ARP030104171A ARP030104171A AR042037A1 AR 042037 A1 AR042037 A1 AR 042037A1 AR P030104171 A ARP030104171 A AR P030104171A AR P030104171 A ARP030104171 A AR P030104171A AR 042037 A1 AR042037 A1 AR 042037A1
- Authority
- AR
- Argentina
- Prior art keywords
- celecoxib
- profarmaco
- pharmaceutically acceptable
- cox
- prodrugs
- Prior art date
Links
- RZEKVGVHFLEQIL-UHFFFAOYSA-N celecoxib Chemical compound C1=CC(C)=CC=C1C1=CC(C(F)(F)F)=NN1C1=CC=C(S(N)(=O)=O)C=C1 RZEKVGVHFLEQIL-UHFFFAOYSA-N 0.000 title abstract 2
- 229960000590 celecoxib Drugs 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 102100038280 Prostaglandin G/H synthase 2 Human genes 0.000 abstract 1
- 108050003267 Prostaglandin G/H synthase 2 Proteins 0.000 abstract 1
- 229940124639 Selective inhibitor Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Profármacos del fármaco inhibidor selectivo de la COX-2 celecoxib y sus sales farmacéuticamente aceptables. Reivindicación 1:Un compuesto que tiene la fórmula 1 o una sal farmacéuticamente aceptable del mismo.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42570302P | 2002-11-12 | 2002-11-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR042037A1 true AR042037A1 (es) | 2005-06-08 |
Family
ID=32313040
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP030104171A AR042037A1 (es) | 2002-11-12 | 2003-11-12 | Profarmaco de celecoxib |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20040092566A1 (es) |
| EP (1) | EP1562910A1 (es) |
| JP (1) | JP2006508123A (es) |
| KR (1) | KR20050072823A (es) |
| CN (1) | CN1711247A (es) |
| AR (1) | AR042037A1 (es) |
| AU (1) | AU2003291278A1 (es) |
| BR (1) | BR0316155A (es) |
| CA (1) | CA2505635A1 (es) |
| CO (1) | CO5700738A2 (es) |
| MX (1) | MXPA05004991A (es) |
| NO (1) | NO20052813L (es) |
| PL (1) | PL376918A1 (es) |
| RU (1) | RU2005114398A (es) |
| TW (1) | TW200424179A (es) |
| WO (1) | WO2004043934A1 (es) |
| ZA (1) | ZA200503188B (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005535642A (ja) | 2002-06-28 | 2005-11-24 | ニトロメッド インコーポレーティッド | オキシムおよび／またはヒドラゾンを含有するニトロソ化および／またはニトロシル化シクロオキシゲナーゼ−２選択的阻害剤、組成物、および使用方法 |
| AU2003303591A1 (en) * | 2002-12-30 | 2004-07-29 | Transform Pharmaceuticals, Inc. | Pharmaceutical compositions with improved dissolution |
| WO2006055404A2 (en) * | 2004-11-16 | 2006-05-26 | Merck & Co., Inc. | Compounds for targeting mechanisms implicated in the progression of stroke |
| CN101805290A (zh) * | 2010-04-01 | 2010-08-18 | 中国人民解放军第四军医大学 | 氨基磺酰吡唑类化合物及其用途 |
| BRPI1003050B1 (pt) * | 2010-08-04 | 2021-05-25 | Universidade Federal De Minas Gerais | Compostos derivados do ácido araquidônico substituídos com análogos de coxibes para tratamento de dor |
| KR101245078B1 (ko) * | 2010-11-11 | 2013-03-18 | 부산대학교 산학협력단 | 대장 선택성 셀레콕시브 전구체 화합물 및 이를 유효성분으로 함유하는 대장성 질환 치료 또는 예방용 약학조성물 |
| WO2013074988A1 (en) * | 2011-11-17 | 2013-05-23 | The Regents Of The University Of Colorado, A Body Corporate | Methods and compositions for enhanced drug delivery to the eye and extended delivery formulations |
| CN104892514A (zh) * | 2015-05-19 | 2015-09-09 | 广州诺威生物技术有限公司 | 一种咪唑类新化合物 |
| CN117050065A (zh) * | 2022-05-05 | 2023-11-14 | 江苏正大清江制药有限公司 | 基于静电喷雾的塞来昔布-维生素e前药纳米粒及其制法及用途 |
| CN117050064A (zh) * | 2022-05-05 | 2023-11-14 | 江苏正大清江制药有限公司 | 一种塞来昔布-维生素e前药及其制法和用途 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TR199802049T2 (xx) * | 1996-04-12 | 1999-01-18 | G.D.Searle & Co. | COX-2 Inhibit�rlerinin �nilac� olarak s�bstit�e edilmi� benzens�lfonamid t�revleri. |
-
2003
- 2003-09-22 US US10/667,622 patent/US20040092566A1/en not_active Abandoned
- 2003-11-03 PL PL376918A patent/PL376918A1/pl not_active Application Discontinuation
- 2003-11-03 MX MXPA05004991A patent/MXPA05004991A/es not_active Application Discontinuation
- 2003-11-03 KR KR1020057008357A patent/KR20050072823A/ko not_active Withdrawn
- 2003-11-03 AU AU2003291278A patent/AU2003291278A1/en not_active Abandoned
- 2003-11-03 CA CA002505635A patent/CA2505635A1/en not_active Abandoned
- 2003-11-03 CN CNA200380103095XA patent/CN1711247A/zh active Pending
- 2003-11-03 BR BR0316155-2A patent/BR0316155A/pt not_active Application Discontinuation
- 2003-11-03 JP JP2004551736A patent/JP2006508123A/ja not_active Withdrawn
- 2003-11-03 RU RU2005114398/04A patent/RU2005114398A/ru not_active Application Discontinuation
- 2003-11-03 EP EP03768668A patent/EP1562910A1/en not_active Withdrawn
- 2003-11-03 WO PCT/US2003/035222 patent/WO2004043934A1/en not_active Ceased
- 2003-11-11 TW TW092131530A patent/TW200424179A/zh unknown
- 2003-11-12 AR ARP030104171A patent/AR042037A1/es unknown
-
2005
- 2005-04-20 ZA ZA200503188A patent/ZA200503188B/en unknown
- 2005-05-11 CO CO05045079A patent/CO5700738A2/es not_active Application Discontinuation
- 2005-06-10 NO NO20052813A patent/NO20052813L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2005114398A (ru) | 2006-01-20 |
| KR20050072823A (ko) | 2005-07-12 |
| BR0316155A (pt) | 2005-09-27 |
| US20040092566A1 (en) | 2004-05-13 |
| NO20052813L (no) | 2005-08-02 |
| WO2004043934A1 (en) | 2004-05-27 |
| TW200424179A (en) | 2004-11-16 |
| NO20052813D0 (no) | 2005-06-10 |
| AU2003291278A1 (en) | 2004-06-03 |
| CA2505635A1 (en) | 2004-05-27 |
| JP2006508123A (ja) | 2006-03-09 |
| ZA200503188B (en) | 2006-11-29 |
| PL376918A1 (pl) | 2006-01-09 |
| CN1711247A (zh) | 2005-12-21 |
| EP1562910A1 (en) | 2005-08-17 |
| MXPA05004991A (es) | 2005-08-02 |
| CO5700738A2 (es) | 2006-11-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |