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AR040521A1 - Gen sisntetico que codifica al factor estimulante de colonias de granulocitos humano para la expresion e. coli - Google Patents

Gen sisntetico que codifica al factor estimulante de colonias de granulocitos humano para la expresion e. coli

Info

Publication number
AR040521A1
AR040521A1 AR20030102715A ARP030102715A AR040521A1 AR 040521 A1 AR040521 A1 AR 040521A1 AR 20030102715 A AR20030102715 A AR 20030102715A AR P030102715 A ARP030102715 A AR P030102715A AR 040521 A1 AR040521 A1 AR 040521A1
Authority
AR
Argentina
Prior art keywords
expression
coli
granulocit
codifying
colonies
Prior art date
Application number
AR20030102715A
Other languages
English (en)
Original Assignee
Lek Pharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lek Pharmaceuticals filed Critical Lek Pharmaceuticals
Publication of AR040521A1 publication Critical patent/AR040521A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/53Colony-stimulating factor [CSF]
    • C07K14/535Granulocyte CSF; Granulocyte-macrophage CSF
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Se refiere al gen sintético que codifica al hG-CSF que permite la expresión en E. Coli con un nivel de expresión mejorado del hG-CSF recombinante respecto de las proteínas celulares totales después de la expresión. Reivindicación 1:Una secuencia de ADN que codifica al hG-CSF caracterizada porque la secuencia comprende la secuencia nucleótida de la SEC ID NO:1.
AR20030102715A 2002-07-31 2003-07-29 Gen sisntetico que codifica al factor estimulante de colonias de granulocitos humano para la expresion e. coli AR040521A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SI200200188A SI21272A (sl) 2002-07-31 2002-07-31 Sintetski gen za humani granulocitne kolonije stimulirajoči dejavnik za ekspresijo v E. coli

Publications (1)

Publication Number Publication Date
AR040521A1 true AR040521A1 (es) 2005-04-06

Family

ID=31493133

Family Applications (1)

Application Number Title Priority Date Filing Date
AR20030102715A AR040521A1 (es) 2002-07-31 2003-07-29 Gen sisntetico que codifica al factor estimulante de colonias de granulocitos humano para la expresion e. coli

Country Status (7)

Country Link
US (1) US7655437B2 (es)
EP (1) EP1527095A1 (es)
JP (1) JP4445466B2 (es)
AR (1) AR040521A1 (es)
AU (1) AU2003253344A1 (es)
SI (1) SI21272A (es)
WO (1) WO2004013175A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2639301T3 (es) 2003-04-30 2017-10-26 Universität Zürich Procedimientos de tratamiento de cáncer usando una inmunotoxina
WO2008128330A1 (en) * 2007-04-19 2008-10-30 Viventia Biotech Inc. Optimized nucleotide sequences of vb6-845 for expression of recombinant proteins
WO2009039630A1 (en) * 2007-09-27 2009-04-02 Viventia Biotech Inc. Optimized nucleic acid sequences for the expression of vb4-845
RU2529363C2 (ru) * 2011-03-02 2014-09-27 Общество с ограниченной ответственностью "Научно-Технологический Центр "БиоИнвест" РЕКОМБИНАНТНАЯ ДНК, КОДИРУЮЩАЯ ГРАНУЛОЦИТАРНЫЙ КОЛОНИЕСТИМУЛИРУЮЩИЙ ФАКТОР ЧЕЛОВЕКА (G-CSF) И РЕКОМБИНАНТНАЯ ПЛАЗМИДА рAS017, ОБЕСПЕЧИВАЮЩАЯ СИНТЕЗ G-CSF В КЛЕТКАХ Escherichia coli
RU2016116549A (ru) 2013-10-02 2017-11-09 Вивентиа Био Инк. Антитела против epcam и способы их применения
CA2979400A1 (en) 2015-03-12 2016-09-15 Viventia Bio Inc. Dosing strategies for targeting epcam positive bladder cancer
WO2016145349A1 (en) 2015-03-12 2016-09-15 Viventia Bio Inc. Methods of treatment for epcam positive bladder cancer

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9004390D0 (en) * 1990-02-27 1990-04-25 Ici Plc Process

Also Published As

Publication number Publication date
SI21272A (sl) 2004-02-29
US20060228781A1 (en) 2006-10-12
JP2006512089A (ja) 2006-04-13
WO2004013175A1 (en) 2004-02-12
EP1527095A1 (en) 2005-05-04
JP4445466B2 (ja) 2010-04-07
US7655437B2 (en) 2010-02-02
AU2003253344A1 (en) 2004-02-23

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