AR039939A1 - MODIFIED PHYTASES - Google Patents
MODIFIED PHYTASESInfo
- Publication number
- AR039939A1 AR039939A1 ARP030101937A ARP030101937A AR039939A1 AR 039939 A1 AR039939 A1 AR 039939A1 AR P030101937 A ARP030101937 A AR P030101937A AR P030101937 A ARP030101937 A AR P030101937A AR 039939 A1 AR039939 A1 AR 039939A1
- Authority
- AR
- Argentina
- Prior art keywords
- phytase
- modified
- model
- phytases
- compared
- Prior art date
Links
- 108010011619 6-Phytase Proteins 0.000 abstract 11
- 229940085127 phytase Drugs 0.000 abstract 8
- 241000228245 Aspergillus niger Species 0.000 abstract 2
- 230000000717 retained effect Effects 0.000 abstract 2
- 125000000539 amino acid group Chemical group 0.000 abstract 1
- 230000002349 favourable effect Effects 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Fodder In General (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
La presente describe fitasas modificadas. Estas fitasas están modificadas en comparación con una fitasa modelo en diversas posiciones, en particular para incrementar la termoestabilidad de la fitasa modificada en comparación con la de la fitasa modelo. Las fitasas modificadas han retenido otras propiedades favorables de la fitasa de Aspergillus niger, en particular porque en la fitasa modificada se han retenido residuos de aminoácidos específicos de la fitasa de Aspergillus niger. Reivindicación 1: Un polipéptido, caracterizado porque cuando se alinea con una fitasa ,modelo está modificado en comparación con dicha fitasa modelo en al menos una de las siguientes posiciones: 5, 6, 13, 19, 21, 29, 31, 36, 39, 43, 53, 69, 78, 81, 85, 87, 99, 112, 113, 122, 125, 126, 128,137,147, 148, 157,160, 163, 165, 169, 172, 176, 178, 180, 181, 182, 183, 189, 194, 197, 201, 203, 211, 213, 215, 218, 222, 223, 225, 232, 233, 242, 246, 247, 248, 249, 250, 251, 252, 254, 269, 291, 296, 310, 312, 315, 322, 330, 342, 346, 362, 365, 367, 368, 372, 374, 375, 382, 384, 395, 414, 417, 425, 428, 438, 440.This describes modified phytases. These phytases are modified compared to a phytase model in various positions, in particular to increase the thermostability of the modified phytase compared to that of the phytase model. Modified phytases have retained other favorable properties of Aspergillus niger phytase, in particular because specific amino acid residues of Aspergillus niger phytase have been retained in the modified phytase. Claim 1: A polypeptide, characterized in that when aligned with a phytase, model is modified compared to said model phytase in at least one of the following positions: 5, 6, 13, 19, 21, 29, 31, 36, 39 , 43, 53, 69, 78, 81, 85, 87, 99, 112, 113, 122, 125, 126, 128,137,147, 148, 157,160, 163, 165, 169, 172, 176, 178, 180, 181, 182 , 183, 189, 194, 197, 201, 203, 211, 213, 215, 218, 222, 223, 225, 232, 233, 242, 246, 247, 248, 249, 250, 251, 252, 254, 269 , 291, 296, 310, 312, 315, 322, 330, 342, 346, 362, 365, 367, 368, 372, 374, 375, 382, 384, 395, 414, 417, 425, 428, 438, 440 .
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02100608 | 2002-05-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR039939A1 true AR039939A1 (en) | 2005-03-09 |
Family
ID=29595046
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP030101936A AR039938A1 (en) | 2002-05-30 | 2003-05-30 | MODIFIED PHYTASES |
| ARP030101937A AR039939A1 (en) | 2002-05-30 | 2003-05-30 | MODIFIED PHYTASES |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP030101936A AR039938A1 (en) | 2002-05-30 | 2003-05-30 | MODIFIED PHYTASES |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP1513931A2 (en) |
| JP (1) | JP2005533492A (en) |
| KR (1) | KR20050038593A (en) |
| CN (1) | CN1656217A (en) |
| AR (2) | AR039938A1 (en) |
| AU (1) | AU2003238448A1 (en) |
| BR (1) | BR0311287A (en) |
| CA (1) | CA2485513A1 (en) |
| MX (1) | MXPA04011224A (en) |
| NO (1) | NO20044802L (en) |
| PE (1) | PE20040537A1 (en) |
| PL (1) | PL372824A1 (en) |
| RU (1) | RU2329301C2 (en) |
| TW (2) | TW200401033A (en) |
| WO (1) | WO2003102174A2 (en) |
| ZA (1) | ZA200410369B (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0422052D0 (en) * | 2004-10-04 | 2004-11-03 | Dansico As | Enzymes |
| WO2007112739A1 (en) | 2006-04-04 | 2007-10-11 | Novozymes A/S | Phytase variants |
| DE102006053059A1 (en) * | 2006-11-10 | 2008-05-15 | Ab Enzymes Gmbh | Polypeptide with phytase activity and increased temperature stability of the enzyme activity and this coding nucleotide sequence |
| CN102854158B (en) * | 2011-07-01 | 2016-01-20 | 北京昕大洋科技发展有限公司 | A kind of method of Fast Measurement phytase heat resistance |
| CN105441406A (en) * | 2014-08-05 | 2016-03-30 | 北京大学 | Phytase variant |
| CN108251439B (en) * | 2018-01-11 | 2021-03-30 | 山西大学 | A kind of artificially modified trypsin-resistant phytase and its preparation method and application |
| CN117683745A (en) * | 2020-04-29 | 2024-03-12 | 南京百斯杰生物工程有限公司 | Parent phytase variant |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2316082A (en) * | 1996-08-13 | 1998-02-18 | Finnfeeds Int Ltd | Phytase |
| EP1151088B1 (en) * | 1999-01-22 | 2006-08-30 | Novozymes A/S | Improved phytases |
-
2003
- 2003-05-28 AU AU2003238448A patent/AU2003238448A1/en not_active Abandoned
- 2003-05-28 CA CA002485513A patent/CA2485513A1/en not_active Abandoned
- 2003-05-28 BR BR0311287-0A patent/BR0311287A/en not_active IP Right Cessation
- 2003-05-28 PL PL03372824A patent/PL372824A1/en not_active Application Discontinuation
- 2003-05-28 WO PCT/EP2003/005729 patent/WO2003102174A2/en not_active Ceased
- 2003-05-28 JP JP2004510416A patent/JP2005533492A/en not_active Withdrawn
- 2003-05-28 EP EP03732516A patent/EP1513931A2/en not_active Withdrawn
- 2003-05-28 MX MXPA04011224A patent/MXPA04011224A/en not_active Application Discontinuation
- 2003-05-28 RU RU2004139054/13A patent/RU2329301C2/en not_active IP Right Cessation
- 2003-05-28 CN CNA03812470XA patent/CN1656217A/en active Pending
- 2003-05-28 KR KR1020047019401A patent/KR20050038593A/en not_active Withdrawn
- 2003-05-30 AR ARP030101936A patent/AR039938A1/en not_active Application Discontinuation
- 2003-05-30 TW TW092114745A patent/TW200401033A/en unknown
- 2003-05-30 PE PE2003000534A patent/PE20040537A1/en not_active Application Discontinuation
- 2003-05-30 TW TW092114788A patent/TW200403341A/en unknown
- 2003-05-30 AR ARP030101937A patent/AR039939A1/en not_active Application Discontinuation
-
2004
- 2004-11-04 NO NO20044802A patent/NO20044802L/en not_active Application Discontinuation
- 2004-12-23 ZA ZA200410369A patent/ZA200410369B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1513931A2 (en) | 2005-03-16 |
| BR0311287A (en) | 2005-03-29 |
| WO2003102174A2 (en) | 2003-12-11 |
| MXPA04011224A (en) | 2005-01-25 |
| KR20050038593A (en) | 2005-04-27 |
| JP2005533492A (en) | 2005-11-10 |
| RU2329301C2 (en) | 2008-07-20 |
| ZA200410369B (en) | 2006-06-28 |
| CN1656217A (en) | 2005-08-17 |
| PL372824A1 (en) | 2005-08-08 |
| TW200401033A (en) | 2004-01-16 |
| CA2485513A1 (en) | 2003-12-11 |
| NO20044802L (en) | 2004-12-08 |
| RU2004139054A (en) | 2005-06-27 |
| AU2003238448A1 (en) | 2003-12-19 |
| TW200403341A (en) | 2004-03-01 |
| WO2003102174A3 (en) | 2004-03-25 |
| AR039938A1 (en) | 2005-03-09 |
| PE20040537A1 (en) | 2004-11-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2423887A1 (en) | Recombinant terminal deoxynucleotidyl transferase with improved functionality | |
| BR0317614A (en) | Process for manufacturing a composition for supplementing animals with amino acid and essential metal complex solutions | |
| MXPA03000510A (en) | Stable salts of o-acetylsalicyclic with basic amino acids. | |
| HRP20090245T1 (en) | Pyy agonists and uses thereof | |
| USD880817S1 (en) | Shirt | |
| USD916430S1 (en) | Leotard | |
| AR039939A1 (en) | MODIFIED PHYTASES | |
| NO20061263L (en) | Kollagenhydrolysat | |
| WO2003020921A3 (en) | Novel pyruvate decarboxylase, production and use thereof | |
| CN207791606U (en) | A new type of cable tie | |
| CN201351656Y (en) | Eye iron nail | |
| CN2568011Y (en) | Anti-drifting necktie | |
| WO2004043287A3 (en) | Novel compositions that enhance production performance in avians | |
| DE602006009099D1 (en) | FISH FOOD WITH SOY PROTEIN | |
| WO2003091274A3 (en) | Use of alpha-s2 casein precursor-derived peptided | |
| UA83996C2 (en) | Pharmaceutical gel preparation comprising peptides, method for producing thereof, kit for producing and use thereof | |
| Leonard | Sri Lankans battle nature | |
| Baggott | My Enemy, Unloved, Has Only Struck One of My Cheeks | |
| RU2002100623A (en) | Lightweight refractory | |
| TH67906S (en) | doll | |
| RU2005100970A (en) | DIGESTIVE ENZYME DRUG | |
| TH28178S1 (en) | bottle | |
| TH86403A (en) | Chromium (III) New Alpha Amino Acid Complex | |
| TH65441A (en) | Monau-and-di-organic amino salts, mono-and di-amino acid salts, and mono- and di-amino acid esters salts of Combritastatin A-4 Phosphate please love. | |
| CA97573S (en) | Self-adhesive label |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |