AR038298A1 - Sales estables del acido o-acetilsalicilico con aminoacidos basicos i i - Google Patents
Sales estables del acido o-acetilsalicilico con aminoacidos basicos i iInfo
- Publication number
- AR038298A1 AR038298A1 ARP030100121A ARP030100121A AR038298A1 AR 038298 A1 AR038298 A1 AR 038298A1 AR P030100121 A ARP030100121 A AR P030100121A AR P030100121 A ARP030100121 A AR P030100121A AR 038298 A1 AR038298 A1 AR 038298A1
- Authority
- AR
- Argentina
- Prior art keywords
- basic amino
- amino acids
- stable salts
- grain size
- medicines
- Prior art date
Links
- 150000001413 amino acids Chemical class 0.000 title abstract 3
- 239000002253 acid Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 3
- 229940079593 drug Drugs 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- GNYWBJRDQHPSJL-UHFFFAOYSA-N 6-acetyl-6-hydroxycyclohexa-2,4-diene-1-carboxylic acid Chemical class CC(=O)C1(O)C=CC=CC1C(O)=O GNYWBJRDQHPSJL-UHFFFAOYSA-N 0.000 abstract 1
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical class CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
- A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Virology (AREA)
- Physiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Biophysics (AREA)
- Nutrition Science (AREA)
- Zoology (AREA)
- Hospice & Palliative Care (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Vascular Medicine (AREA)
- Obesity (AREA)
Abstract
Composiciones mejoradas con sales estables del ácido o-acetilsalicílico con aminoácidos básicos, a medicamentos que las contienen así como a su uso para la fabricación de medicamentos. Reivindicación 1: Composición que comprende una sal del ácido o-acetilsalicílico con un aminoácido básico que presenta en una distribución de tamanos de grano medida en condiciones estándar con un aparato Malvern 2600D un tamano medio de grano superior a un tamano de grano de 160 micrones y una proporción de más del 60% de las partículas con un tamano de grano en un intervalo de 100 a 200 micrones, caracterizada porque la composición comprende adicionalmente un agente de fluencia y/o está granulada.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10202019A DE10202019A1 (de) | 2002-01-18 | 2002-01-18 | Stabile Salze von o-Acetylsalicylsäure mit basischen Aminosäuren II |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR038298A1 true AR038298A1 (es) | 2005-01-12 |
Family
ID=7712593
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP030100121A AR038298A1 (es) | 2002-01-18 | 2003-01-16 | Sales estables del acido o-acetilsalicilico con aminoacidos basicos i i |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US20050171070A1 (es) |
| EP (1) | EP1469835B1 (es) |
| JP (1) | JP2005519892A (es) |
| KR (1) | KR20040079936A (es) |
| CN (1) | CN1298314C (es) |
| AR (1) | AR038298A1 (es) |
| AT (1) | ATE378040T1 (es) |
| AU (1) | AU2003235700B2 (es) |
| BR (1) | BR0307009A (es) |
| CA (1) | CA2473893A1 (es) |
| CO (1) | CO5611102A2 (es) |
| CU (1) | CU20040161A7 (es) |
| DE (2) | DE10202019A1 (es) |
| EC (1) | ECSP045192A (es) |
| ES (1) | ES2297166T3 (es) |
| GT (1) | GT200300004A (es) |
| HN (1) | HN2003000015A (es) |
| HR (1) | HRP20040742B1 (es) |
| IL (1) | IL162881A0 (es) |
| MX (1) | MXPA04006832A (es) |
| NO (1) | NO20043404L (es) |
| NZ (1) | NZ534128A (es) |
| PE (1) | PE20030731A1 (es) |
| PL (1) | PL370197A1 (es) |
| RS (1) | RS63804A (es) |
| SV (1) | SV2004001457A (es) |
| TW (1) | TWI265810B (es) |
| UY (1) | UY27612A1 (es) |
| WO (1) | WO2003059323A2 (es) |
| ZA (1) | ZA200405533B (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004025535A1 (de) * | 2004-05-25 | 2005-12-22 | Bayer Healthcare Ag | Kombination von Salzen der o-Acetylsalicylsäure und Alpha-Glucosidase-Inhibitoren |
| DE102005025283A1 (de) * | 2005-06-02 | 2006-12-07 | Bayer Healthcare Ag | Stabiler Wirkstoffkomplex von Salzen der o-Acetylsalicylsäure mit basischen Aminosäuren und Glycin |
| DE102005049293A1 (de) * | 2005-10-15 | 2007-04-26 | Bayer Healthcare Ag | Kombinationspräparate von Salzen oder o-Acetylsalicylsäure |
| DE102008004386A1 (de) | 2008-01-14 | 2009-07-23 | Activaero Gmbh | Verwendung eines Acetylsalicylsäuresalzes zur Behandlung viraler Infektionen |
| JP5309977B2 (ja) * | 2008-12-26 | 2013-10-09 | ライオン株式会社 | チュアブル錠 |
| US8173625B2 (en) | 2009-05-08 | 2012-05-08 | Theaprin Pharmaceuticals Inc. | Intravenous formulation with water-soluble cocrystals of acetylsalicylic acid and theanine |
| CA2766048A1 (en) * | 2009-06-25 | 2010-12-29 | Tetra, Sia | Novel acetylsalicylic acid salts |
| JP5563835B2 (ja) * | 2010-01-15 | 2014-07-30 | 全星薬品工業株式会社 | アスピリン錠剤の製造方法 |
| ITMI20121144A1 (it) * | 2012-06-28 | 2013-12-29 | Dipharma Francis Srl | Procedimento per la preparazione di un sale di un farmaco antinfiammatorio non steroideo |
| US10882811B2 (en) | 2016-12-23 | 2021-01-05 | Aspiair Gmbh | Synthesis of lysine acetylsalicylate glycine particles |
| RU2738831C1 (ru) * | 2020-03-03 | 2020-12-17 | федеральное государственное бюджетное образовательное учреждение высшего образования "Ростовский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО РостГМУ Минздрава России) | Способ консервативного лечения невралгии тройничного нерва |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5610110A (en) * | 1979-07-06 | 1981-02-02 | Green Cross Corp:The | Acetyl salicylate salt preparation for injection |
| FR2611501B1 (fr) * | 1987-03-04 | 1991-12-06 | Corbiere Jerome | Nouvelles compositions pharmaceutiques pour la voie buccale a base d'acetylsalielylate de lysine et leur procede d'obtention |
| DE10034802A1 (de) * | 2000-07-18 | 2002-01-31 | Bayer Ag | Stabile Salze von O-Acetylsalicylsäure mit basischen Aminosäuren |
-
2002
- 2002-01-18 DE DE10202019A patent/DE10202019A1/de not_active Withdrawn
-
2003
- 2003-01-07 AT AT03729426T patent/ATE378040T1/de not_active IP Right Cessation
- 2003-01-07 IL IL16288103A patent/IL162881A0/xx unknown
- 2003-01-07 PL PL03370197A patent/PL370197A1/xx not_active Application Discontinuation
- 2003-01-07 CA CA002473893A patent/CA2473893A1/en not_active Abandoned
- 2003-01-07 AU AU2003235700A patent/AU2003235700B2/en not_active Ceased
- 2003-01-07 ES ES03729426T patent/ES2297166T3/es not_active Expired - Lifetime
- 2003-01-07 DE DE50308596T patent/DE50308596D1/de not_active Expired - Lifetime
- 2003-01-07 RS YU63804A patent/RS63804A/sr unknown
- 2003-01-07 JP JP2003559486A patent/JP2005519892A/ja active Pending
- 2003-01-07 MX MXPA04006832A patent/MXPA04006832A/es active IP Right Grant
- 2003-01-07 KR KR10-2004-7011078A patent/KR20040079936A/ko not_active Ceased
- 2003-01-07 EP EP03729426A patent/EP1469835B1/de not_active Expired - Lifetime
- 2003-01-07 BR BR0307009-3A patent/BR0307009A/pt not_active IP Right Cessation
- 2003-01-07 CN CNB038064154A patent/CN1298314C/zh not_active Expired - Fee Related
- 2003-01-07 WO PCT/EP2003/000059 patent/WO2003059323A2/de not_active Ceased
- 2003-01-07 NZ NZ534128A patent/NZ534128A/en not_active IP Right Cessation
- 2003-01-07 US US10/501,677 patent/US20050171070A1/en not_active Abandoned
- 2003-01-07 HR HR20040742A patent/HRP20040742B1/xx not_active IP Right Cessation
- 2003-01-14 GT GT200300004A patent/GT200300004A/es unknown
- 2003-01-15 UY UY27612A patent/UY27612A1/es not_active Application Discontinuation
- 2003-01-16 AR ARP030100121A patent/AR038298A1/es not_active Application Discontinuation
- 2003-01-17 TW TW092100932A patent/TWI265810B/zh not_active IP Right Cessation
- 2003-01-17 SV SV2003001457A patent/SV2004001457A/es unknown
- 2003-01-17 HN HN2003000015A patent/HN2003000015A/es unknown
- 2003-01-17 PE PE2003000052A patent/PE20030731A1/es not_active Application Discontinuation
-
2004
- 2004-07-13 ZA ZA200405533A patent/ZA200405533B/en unknown
- 2004-07-15 EC EC2004005192A patent/ECSP045192A/es unknown
- 2004-07-19 CU CU20040161A patent/CU20040161A7/es unknown
- 2004-08-16 NO NO20043404A patent/NO20043404L/no not_active Application Discontinuation
- 2004-08-17 CO CO04079945A patent/CO5611102A2/es not_active Application Discontinuation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR030305A1 (es) | Composicion que comprende sales de acido o-acetilsalicilico con aminoacidos basicos, un procedimiento para su preparacion, uso de dicha composicion para la manufactura de un medicamento | |
| AR038298A1 (es) | Sales estables del acido o-acetilsalicilico con aminoacidos basicos i i | |
| CO6331421A2 (es) | Gel de quitosano para aplicaciones dermatologicas proceso de obtencion y uso del mismo | |
| ES2075011T3 (es) | Uso de sales del acido gamma-hidroxibutirico para preparar composiciones farmaceuticas para uso en el tratamiento del alcoholismo, y las composiciones obtenidas. | |
| YU2503A (sh) | Oksigenovani estri 4-jodo fenilamino benzhidroksamskih kiselina | |
| ATE487470T1 (de) | Gel-stabilisierte wirkstoff-zusammensetzungen in nanoteilchengrösse | |
| GB2459809A (en) | Fatty acid formulations and methods of use thereof | |
| AR065887A1 (es) | Producto para el cuidado oral y metodos de uso y fabricacion de los mismos | |
| AR038375A1 (es) | Composiciones farmaceuticas de inhibidores de la proteina de transferencia de esteres de colesterilo | |
| AR018704A1 (es) | Parche con efecto de campo magnetico | |
| ATE466611T1 (de) | Ausgabevorrichtungen und flüssigformulierungen | |
| BR9914932A (pt) | Processo para a manufatura de uma composição de isotretinoìna, composição de isotretinoìna micronizada, forma de dosagem unitária para administração enteral e composição farmacêutica na forma de dosagem unitária | |
| CY1108700T1 (el) | Συνθεσεις απελευθερωσης φαρμακου εστερα αλφα-υδροξυ οξεος και μεθοδοι χρησης | |
| BRPI0508063A (pt) | processo para a manufatura de uma composição farmacêutica, nsaid, e, composição farmacêutica | |
| BR112012026223A2 (pt) | formulação adequada para o uso em ração animal, uso, e ração para animais. | |
| IT1141482B (it) | Sali misti di amminoacidi essenziali o semi-essenziali e loro analoghi non azotati,nonche' loro impiego nella terapia di disfunzioni renali ed epatiche | |
| ES2194679T3 (es) | Composiciones cosmeticas que contienen creatina, carnitina y/o acido piruvico. | |
| BR0315808A (pt) | Composições biocìdicas aquosa e sólida contendo bromo ativo e processo de produção destas | |
| RU2015122627A (ru) | Кожные композиции, содержащие неприродные гигроскопические аминокислоты | |
| BRPI0413957A (pt) | processo para preparar diterpenos solúveis em água, solução aquosa e suas aplicações | |
| BRPI0416215A (pt) | forma de ministração individualmente dosada, não comprimida, processo para produzir uma forma de ministração individualmente dosada, não comprimida e uso de pelo menos um agente de estabilização | |
| LV11818A (lv) | Jauna farmaceitiska kompozicija stabilas pulverveida zalu formas pagatavosanai | |
| NO20033704L (no) | Fremgangsmåte for fremstilling av D-pantotensyre og/eller salter som tilsetning til dyrefôr | |
| CN107308032A (zh) | 一种新式酵素纳米洗发液 | |
| Queiroz et al. | Report of two microabrasion techniques of enamel to remove stains and discussion |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |